Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	100505591
Gene name	Leucine rich repeat containing 3C
Gene symbol	LRRC3C
Synonyms (NCBI Gene)	-
Chromosome	17
Chromosome location	17q21.1

152

Show/Hide all (152)

miRTarBase ID	miRNA	Experiments	Reference
MIRT717157	hsa-miR-186-5p	HITS-CLIP	19536157
MIRT717156	hsa-miR-584-3p	HITS-CLIP	19536157
MIRT717155	hsa-miR-4277	HITS-CLIP	19536157
MIRT717154	hsa-miR-6715b-3p	HITS-CLIP	19536157
MIRT717153	hsa-miR-155-3p	HITS-CLIP	19536157
MIRT717152	hsa-miR-30b-5p	HITS-CLIP	19536157
MIRT717151	hsa-miR-30c-5p	HITS-CLIP	19536157
MIRT692180	hsa-miR-7846-3p	HITS-CLIP	23313552
MIRT692179	hsa-miR-1273g-3p	HITS-CLIP	23313552
MIRT692178	hsa-miR-4722-3p	HITS-CLIP	23313552
MIRT692177	hsa-miR-6727-3p	HITS-CLIP	23313552
MIRT692176	hsa-miR-6747-3p	HITS-CLIP	23313552
MIRT692175	hsa-miR-4793-3p	HITS-CLIP	23313552
MIRT692174	hsa-miR-4252	HITS-CLIP	23313552
MIRT692173	hsa-miR-4683	HITS-CLIP	23313552
MIRT692172	hsa-miR-7703	HITS-CLIP	23313552
MIRT662764	hsa-miR-6856-3p	HITS-CLIP	23824327
MIRT662763	hsa-miR-6769a-3p	HITS-CLIP	23824327
MIRT662762	hsa-miR-6887-3p	HITS-CLIP	23824327
MIRT662761	hsa-miR-4667-3p	HITS-CLIP	23824327
MIRT662760	hsa-miR-4780	HITS-CLIP	23824327
MIRT662759	hsa-miR-6780b-3p	HITS-CLIP	23824327
MIRT662758	hsa-miR-5193	HITS-CLIP	23824327
MIRT662757	hsa-miR-532-3p	HITS-CLIP	23824327
MIRT662756	hsa-miR-4287	HITS-CLIP	23824327
MIRT662755	hsa-miR-4685-3p	HITS-CLIP	23824327
MIRT662754	hsa-miR-4749-3p	HITS-CLIP	23824327
MIRT662753	hsa-miR-7106-3p	HITS-CLIP	23824327
MIRT662752	hsa-miR-623	HITS-CLIP	23824327
MIRT662751	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT662750	hsa-miR-6772-3p	HITS-CLIP	23824327
MIRT662749	hsa-miR-4714-3p	HITS-CLIP	23824327
MIRT662748	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT662747	hsa-miR-6736-3p	HITS-CLIP	23824327
MIRT662746	hsa-miR-660-3p	HITS-CLIP	23824327
MIRT662745	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT662744	hsa-miR-6787-3p	HITS-CLIP	23824327
MIRT662743	hsa-miR-4772-3p	HITS-CLIP	23824327
MIRT662742	hsa-miR-7114-5p	HITS-CLIP	23824327
MIRT662741	hsa-miR-134-3p	HITS-CLIP	23824327
MIRT662740	hsa-miR-4695-3p	HITS-CLIP	23824327
MIRT662739	hsa-miR-6499-3p	HITS-CLIP	23824327
MIRT662738	hsa-miR-3135b	HITS-CLIP	23824327
MIRT662737	hsa-miR-504-3p	HITS-CLIP	23824327
MIRT662736	hsa-miR-122-5p	HITS-CLIP	23824327
MIRT662735	hsa-miR-3136-3p	HITS-CLIP	23824327
MIRT662734	hsa-miR-7155-3p	HITS-CLIP	23824327
MIRT662733	hsa-miR-3652	HITS-CLIP	23824327
MIRT662732	hsa-miR-4430	HITS-CLIP	23824327
MIRT662731	hsa-miR-5698	HITS-CLIP	23824327
MIRT662730	hsa-miR-3650	HITS-CLIP	23824327
MIRT662729	hsa-miR-143-5p	HITS-CLIP	23824327
MIRT662728	hsa-miR-663b	HITS-CLIP	23824327
MIRT662727	hsa-miR-7641	HITS-CLIP	23824327
MIRT662726	hsa-miR-7108-5p	HITS-CLIP	23824327
MIRT662725	hsa-miR-3689d	HITS-CLIP	23824327
MIRT569199	hsa-miR-4524b-3p	PAR-CLIP	20371350
MIRT569198	hsa-miR-6760-5p	PAR-CLIP	20371350
MIRT569197	hsa-miR-4459	PAR-CLIP	20371350
MIRT569196	hsa-miR-1253	PAR-CLIP	20371350
MIRT569195	hsa-miR-4419a	PAR-CLIP	20371350
MIRT569194	hsa-miR-4510	PAR-CLIP	20371350
MIRT569193	hsa-miR-6127	PAR-CLIP	20371350
MIRT569192	hsa-miR-6129	PAR-CLIP	20371350
MIRT569191	hsa-miR-6130	PAR-CLIP	20371350
MIRT569190	hsa-miR-6133	PAR-CLIP	20371350
MIRT569189	hsa-miR-658	PAR-CLIP	20371350
MIRT569188	hsa-miR-4434	PAR-CLIP	20371350
MIRT569187	hsa-miR-4516	PAR-CLIP	20371350
MIRT569186	hsa-miR-5703	PAR-CLIP	20371350
MIRT569185	hsa-miR-765	PAR-CLIP	20371350
MIRT569184	hsa-miR-1249-5p	PAR-CLIP	20371350
MIRT569182	hsa-miR-6797-5p	PAR-CLIP	20371350
MIRT569183	hsa-miR-25-5p	PAR-CLIP	20371350
MIRT569181	hsa-miR-6878-5p	PAR-CLIP	20371350
MIRT569180	hsa-miR-4298	PAR-CLIP	20371350
MIRT717157	hsa-miR-186-5p	HITS-CLIP	19536157
MIRT717156	hsa-miR-584-3p	HITS-CLIP	19536157
MIRT717155	hsa-miR-4277	HITS-CLIP	19536157
MIRT717154	hsa-miR-6715b-3p	HITS-CLIP	19536157
MIRT717153	hsa-miR-155-3p	HITS-CLIP	19536157
MIRT717152	hsa-miR-30b-5p	HITS-CLIP	19536157
MIRT717151	hsa-miR-30c-5p	HITS-CLIP	19536157
MIRT692180	hsa-miR-7846-3p	HITS-CLIP	23313552
MIRT692179	hsa-miR-1273g-3p	HITS-CLIP	23313552
MIRT692178	hsa-miR-4722-3p	HITS-CLIP	23313552
MIRT692177	hsa-miR-6727-3p	HITS-CLIP	23313552
MIRT692176	hsa-miR-6747-3p	HITS-CLIP	23313552
MIRT692175	hsa-miR-4793-3p	HITS-CLIP	23313552
MIRT692174	hsa-miR-4252	HITS-CLIP	23313552
MIRT692173	hsa-miR-4683	HITS-CLIP	23313552
MIRT692172	hsa-miR-7703	HITS-CLIP	23313552
MIRT662764	hsa-miR-6856-3p	HITS-CLIP	23824327
MIRT662763	hsa-miR-6769a-3p	HITS-CLIP	23824327
MIRT662762	hsa-miR-6887-3p	HITS-CLIP	23824327
MIRT662761	hsa-miR-4667-3p	HITS-CLIP	23824327
MIRT662760	hsa-miR-4780	HITS-CLIP	23824327
MIRT662759	hsa-miR-6780b-3p	HITS-CLIP	23824327
MIRT662758	hsa-miR-5193	HITS-CLIP	23824327
MIRT662757	hsa-miR-532-3p	HITS-CLIP	23824327
MIRT662756	hsa-miR-4287	HITS-CLIP	23824327
MIRT662755	hsa-miR-4685-3p	HITS-CLIP	23824327
MIRT662754	hsa-miR-4749-3p	HITS-CLIP	23824327
MIRT662753	hsa-miR-7106-3p	HITS-CLIP	23824327
MIRT662752	hsa-miR-623	HITS-CLIP	23824327
MIRT662751	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT662750	hsa-miR-6772-3p	HITS-CLIP	23824327
MIRT662749	hsa-miR-4714-3p	HITS-CLIP	23824327
MIRT662748	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT662747	hsa-miR-6736-3p	HITS-CLIP	23824327
MIRT662746	hsa-miR-660-3p	HITS-CLIP	23824327
MIRT662745	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT662744	hsa-miR-6787-3p	HITS-CLIP	23824327
MIRT662743	hsa-miR-4772-3p	HITS-CLIP	23824327
MIRT662742	hsa-miR-7114-5p	HITS-CLIP	23824327
MIRT662741	hsa-miR-134-3p	HITS-CLIP	23824327
MIRT662740	hsa-miR-4695-3p	HITS-CLIP	23824327
MIRT662739	hsa-miR-6499-3p	HITS-CLIP	23824327
MIRT662738	hsa-miR-3135b	HITS-CLIP	23824327
MIRT662737	hsa-miR-504-3p	HITS-CLIP	23824327
MIRT662736	hsa-miR-122-5p	HITS-CLIP	23824327
MIRT662735	hsa-miR-3136-3p	HITS-CLIP	23824327
MIRT662734	hsa-miR-7155-3p	HITS-CLIP	23824327
MIRT662733	hsa-miR-3652	HITS-CLIP	23824327
MIRT662732	hsa-miR-4430	HITS-CLIP	23824327
MIRT662731	hsa-miR-5698	HITS-CLIP	23824327
MIRT662730	hsa-miR-3650	HITS-CLIP	23824327
MIRT662729	hsa-miR-143-5p	HITS-CLIP	23824327
MIRT662728	hsa-miR-663b	HITS-CLIP	23824327
MIRT662727	hsa-miR-7641	HITS-CLIP	23824327
MIRT662726	hsa-miR-7108-5p	HITS-CLIP	23824327
MIRT662725	hsa-miR-3689d	HITS-CLIP	23824327
MIRT569199	hsa-miR-4524b-3p	PAR-CLIP	20371350
MIRT569198	hsa-miR-6760-5p	PAR-CLIP	20371350
MIRT569197	hsa-miR-4459	PAR-CLIP	20371350
MIRT569196	hsa-miR-1253	PAR-CLIP	20371350
MIRT569195	hsa-miR-4419a	PAR-CLIP	20371350
MIRT569194	hsa-miR-4510	PAR-CLIP	20371350
MIRT569193	hsa-miR-6127	PAR-CLIP	20371350
MIRT569192	hsa-miR-6129	PAR-CLIP	20371350
MIRT569191	hsa-miR-6130	PAR-CLIP	20371350
MIRT569190	hsa-miR-6133	PAR-CLIP	20371350
MIRT569189	hsa-miR-658	PAR-CLIP	20371350
MIRT569188	hsa-miR-4434	PAR-CLIP	20371350
MIRT569187	hsa-miR-4516	PAR-CLIP	20371350
MIRT569186	hsa-miR-5703	PAR-CLIP	20371350
MIRT569185	hsa-miR-765	PAR-CLIP	20371350
MIRT569184	hsa-miR-1249-5p	PAR-CLIP	20371350
MIRT569182	hsa-miR-6797-5p	PAR-CLIP	20371350
MIRT569183	hsa-miR-25-5p	PAR-CLIP	20371350
MIRT569181	hsa-miR-6878-5p	PAR-CLIP	20371350
MIRT569180	hsa-miR-4298	PAR-CLIP	20371350

Show/Hide all (3)

GO ID	Ontology	Definition	Evidence
GO:0005886	Component	Plasma membrane	IBA
GO:0016020	Component	Membrane	IEA
GO:0038023	Function	Signaling receptor activity	IBA

MIM	HGNC	e!Ensembl
HGNC	N/A	HGNC

A6NJW4

Protein name

Leucine-rich repeat-containing protein 3C

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF13855	LRR_8	80 → 140	Leucine rich repeat	Repeat

Sequence

MRMTSSSFVSYCTPGLCQFMAMLPTAGHLLPLLLVIGTGGTVPSPQVPPRGCYVAKEAGE
RTFRCSQAGLSAVPSGIPNDTRKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSG
AAFQGLEGTLRHLDLSANQLASVPVEAFVGLQIQVNLSANPWHCDCALQEVLRQVRLVPG
TGTGIVCGSGARPDLVGQEFLLLAGEEELCGSGWGGARRSTDVALLVTMGGWLTLMVAYL
VHYVWQNRDETRRSLKRAPVLPVRSEDSSILSTVV

Sequence length

275

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (7)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
ASTHMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
BIPOLAR DISORDER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
BIPOLAR I DISORDER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CARDIOVASCULAR DISEASE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CHILDHOOD ONSET ASTHMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
INFLAMMATORY BOWEL DISEASE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ULCERATIVE COLITIS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (4)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Childhood asthma	Asthma	GWASDB_DG	17611496		★★★★★ ★☆☆☆☆ Found in Text Mining only
Crohn Disease	Crohn Disease	BEFREE	26484354		★★★★★ ★☆☆☆☆ Found in Text Mining only
Inflammatory Bowel Diseases	Inflammatory Bowel Disease	BEFREE	26484354		★★★★★ ★☆☆☆☆ Found in Text Mining only
Inflammatory Bowel Diseases	Inflammatory bowel disease	Pubtator	26484354	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only

LRRC3C (leucine rich repeat containing 3C)