HMGXB4 (HMG-box containing 4)

Gene

• Entrez ID: 10042
• Gene name: HMG-box containing 4
• Gene symbol: HMGXB4
• Synonyms (NCBI Gene): HMG2L1, HMGBCG, P53N, THC211630
• Chromosome: 22
• Chromosome location: 22q12.3
• Summary: High mobility group (HMG) proteins are nonhistone chromosomal proteins. See HMG2 (MIM 163906) for additional information on HMG proteins.[supplied by OMIM, Nov 2010]

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT021175	hsa-miR-186-5p	Sequencing	20371350
MIRT003368	hsa-miR-221-3p	Reporter assay;Microarray	20018759
MIRT047935	hsa-miR-30c-5p	CLASH	23622248
MIRT352642	hsa-miR-493-5p	HITS-CLIP	21572407
MIRT511496	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT352641	hsa-miR-323a-3p	HITS-CLIP	21572407
MIRT511498	hsa-miR-3163	HITS-CLIP	21572407
MIRT205686	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT352644	hsa-miR-4528	HITS-CLIP	21572407
MIRT511497	hsa-miR-567	HITS-CLIP	21572407
MIRT205681	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT205685	hsa-miR-3924	HITS-CLIP	21572407
MIRT205684	hsa-miR-297	HITS-CLIP	21572407
MIRT352642	hsa-miR-493-5p	PAR-CLIP	20371350
MIRT511496	hsa-miR-1277-5p	PAR-CLIP	20371350
MIRT352641	hsa-miR-323a-3p	PAR-CLIP	20371350
MIRT352644	hsa-miR-4528	PAR-CLIP	20371350
MIRT511497	hsa-miR-567	PAR-CLIP	20371350
MIRT352639	hsa-let-7a-2-3p	PAR-CLIP	20371350
MIRT352640	hsa-let-7g-3p	PAR-CLIP	20371350
MIRT205684	hsa-miR-297	PAR-CLIP	20371350
MIRT236405	hsa-miR-5586-3p	PAR-CLIP	21572407
MIRT236403	hsa-miR-3174	PAR-CLIP	21572407
MIRT236404	hsa-miR-4693-3p	PAR-CLIP	21572407
MIRT236402	hsa-miR-2052	PAR-CLIP	21572407
MIRT236399	hsa-miR-19a-5p	PAR-CLIP	21572407
MIRT236400	hsa-miR-19b-1-5p	PAR-CLIP	21572407
MIRT236401	hsa-miR-19b-2-5p	PAR-CLIP	21572407
MIRT557258	hsa-miR-106a-3p	PAR-CLIP	21572407
MIRT557259	hsa-miR-450b-5p	PAR-CLIP	21572407
MIRT557257	hsa-miR-507	PAR-CLIP	21572407
MIRT557256	hsa-miR-557	PAR-CLIP	21572407
MIRT557255	hsa-miR-3680-3p	PAR-CLIP	21572407
MIRT557254	hsa-miR-129-5p	PAR-CLIP	21572407
MIRT352642	hsa-miR-493-5p	PAR-CLIP	23446348
MIRT352641	hsa-miR-323a-3p	PAR-CLIP	23446348
MIRT511498	hsa-miR-3163	PAR-CLIP	23446348
MIRT205686	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT352644	hsa-miR-4528	PAR-CLIP	23446348
MIRT511497	hsa-miR-567	PAR-CLIP	23446348
MIRT205681	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT205685	hsa-miR-3924	PAR-CLIP	23446348
MIRT087686	hsa-let-7c-3p	PAR-CLIP	23446348
MIRT352639	hsa-let-7a-2-3p	PAR-CLIP	23446348
MIRT352640	hsa-let-7g-3p	PAR-CLIP	23446348
MIRT205684	hsa-miR-297	PAR-CLIP	23446348
MIRT511496	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT352663	hsa-miR-3154	PAR-CLIP	23592263
MIRT475589	hsa-miR-4496	PAR-CLIP	23592263
MIRT475588	hsa-miR-1321	PAR-CLIP	23592263
MIRT475587	hsa-miR-4739	PAR-CLIP	23592263
MIRT475586	hsa-miR-4756-5p	PAR-CLIP	23592263
MIRT475585	hsa-miR-3141	PAR-CLIP	23592263
MIRT475584	hsa-miR-4261	PAR-CLIP	23592263
MIRT475583	hsa-miR-149-3p	PAR-CLIP	23592263
MIRT475581	hsa-miR-4728-5p	PAR-CLIP	23592263
MIRT475582	hsa-miR-6785-5p	PAR-CLIP	23592263
MIRT475580	hsa-miR-6883-5p	PAR-CLIP	23592263
MIRT475579	hsa-miR-4716-3p	PAR-CLIP	23592263
MIRT475578	hsa-miR-6809-5p	PAR-CLIP	23592263
MIRT440490	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT440490	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT727491	hsa-miR-27a-3p	HITS-CLIP	22473208
MIRT727490	hsa-miR-27b-3p	HITS-CLIP	22473208
MIRT352642	hsa-miR-493-5p	HITS-CLIP	21572407
MIRT511496	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT352641	hsa-miR-323a-3p	HITS-CLIP	21572407
MIRT511498	hsa-miR-3163	HITS-CLIP	21572407
MIRT205686	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT352644	hsa-miR-4528	HITS-CLIP	21572407
MIRT511497	hsa-miR-567	HITS-CLIP	21572407
MIRT205681	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT205685	hsa-miR-3924	HITS-CLIP	21572407
MIRT205684	hsa-miR-297	HITS-CLIP	21572407
MIRT352642	hsa-miR-493-5p	PAR-CLIP	20371350
MIRT511496	hsa-miR-1277-5p	PAR-CLIP	20371350
MIRT352641	hsa-miR-323a-3p	PAR-CLIP	20371350
MIRT352644	hsa-miR-4528	PAR-CLIP	20371350
MIRT511497	hsa-miR-567	PAR-CLIP	20371350
MIRT352639	hsa-let-7a-2-3p	PAR-CLIP	20371350
MIRT352640	hsa-let-7g-3p	PAR-CLIP	20371350
MIRT205684	hsa-miR-297	PAR-CLIP	20371350
MIRT236405	hsa-miR-5586-3p	PAR-CLIP	21572407
MIRT236403	hsa-miR-3174	PAR-CLIP	21572407
MIRT236404	hsa-miR-4693-3p	PAR-CLIP	21572407
MIRT236402	hsa-miR-2052	PAR-CLIP	21572407
MIRT236399	hsa-miR-19a-5p	PAR-CLIP	21572407
MIRT236400	hsa-miR-19b-1-5p	PAR-CLIP	21572407
MIRT236401	hsa-miR-19b-2-5p	PAR-CLIP	21572407
MIRT557258	hsa-miR-106a-3p	PAR-CLIP	21572407
MIRT557259	hsa-miR-450b-5p	PAR-CLIP	21572407
MIRT557257	hsa-miR-507	PAR-CLIP	21572407
MIRT557256	hsa-miR-557	PAR-CLIP	21572407
MIRT557255	hsa-miR-3680-3p	PAR-CLIP	21572407
MIRT557254	hsa-miR-129-5p	PAR-CLIP	21572407
MIRT352642	hsa-miR-493-5p	PAR-CLIP	23446348
MIRT352641	hsa-miR-323a-3p	PAR-CLIP	23446348
MIRT511498	hsa-miR-3163	PAR-CLIP	23446348
MIRT205686	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT352644	hsa-miR-4528	PAR-CLIP	23446348
MIRT511497	hsa-miR-567	PAR-CLIP	23446348
MIRT205681	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT205685	hsa-miR-3924	PAR-CLIP	23446348
MIRT087686	hsa-let-7c-3p	PAR-CLIP	23446348
MIRT352639	hsa-let-7a-2-3p	PAR-CLIP	23446348
MIRT352640	hsa-let-7g-3p	PAR-CLIP	23446348
MIRT205684	hsa-miR-297	PAR-CLIP	23446348
MIRT511496	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT352663	hsa-miR-3154	PAR-CLIP	23592263
MIRT475589	hsa-miR-4496	PAR-CLIP	23592263
MIRT475588	hsa-miR-1321	PAR-CLIP	23592263
MIRT475587	hsa-miR-4739	PAR-CLIP	23592263
MIRT475586	hsa-miR-4756-5p	PAR-CLIP	23592263
MIRT475585	hsa-miR-3141	PAR-CLIP	23592263
MIRT475584	hsa-miR-4261	PAR-CLIP	23592263
MIRT475583	hsa-miR-149-3p	PAR-CLIP	23592263
MIRT475581	hsa-miR-4728-5p	PAR-CLIP	23592263
MIRT475582	hsa-miR-6785-5p	PAR-CLIP	23592263
MIRT475580	hsa-miR-6883-5p	PAR-CLIP	23592263
MIRT475579	hsa-miR-4716-3p	PAR-CLIP	23592263
MIRT475578	hsa-miR-6809-5p	PAR-CLIP	23592263
MIRT1050031	hsa-let-7a	CLIP-seq
MIRT1050032	hsa-let-7b	CLIP-seq
MIRT1050033	hsa-let-7c	CLIP-seq
MIRT1050034	hsa-let-7d	CLIP-seq
MIRT1050035	hsa-let-7e	CLIP-seq
MIRT1050036	hsa-let-7f	CLIP-seq
MIRT1050037	hsa-let-7g	CLIP-seq
MIRT1050038	hsa-let-7i	CLIP-seq
MIRT1050039	hsa-miR-1	CLIP-seq
MIRT1050040	hsa-miR-124	CLIP-seq
MIRT1050041	hsa-miR-1304	CLIP-seq
MIRT1050042	hsa-miR-186	CLIP-seq
MIRT1050043	hsa-miR-202	CLIP-seq
MIRT1050044	hsa-miR-206	CLIP-seq
MIRT1050045	hsa-miR-298	CLIP-seq
MIRT1050046	hsa-miR-3124-3p	CLIP-seq
MIRT1050047	hsa-miR-3190	CLIP-seq
MIRT1050048	hsa-miR-337-3p	CLIP-seq
MIRT1050049	hsa-miR-3617	CLIP-seq
MIRT1050050	hsa-miR-3673	CLIP-seq
MIRT1050051	hsa-miR-3685	CLIP-seq
MIRT1050052	hsa-miR-3714	CLIP-seq
MIRT1050053	hsa-miR-384	CLIP-seq
MIRT1050054	hsa-miR-3910	CLIP-seq
MIRT1050055	hsa-miR-3942-3p	CLIP-seq
MIRT1050056	hsa-miR-4276	CLIP-seq
MIRT1050057	hsa-miR-4427	CLIP-seq
MIRT1050058	hsa-miR-4458	CLIP-seq
MIRT1050059	hsa-miR-4491	CLIP-seq
MIRT1050060	hsa-miR-4494	CLIP-seq
MIRT1050061	hsa-miR-4500	CLIP-seq
MIRT1050062	hsa-miR-4642	CLIP-seq
MIRT1050063	hsa-miR-4657	CLIP-seq
MIRT1050064	hsa-miR-4666-5p	CLIP-seq
MIRT1050065	hsa-miR-4680-3p	CLIP-seq
MIRT1050066	hsa-miR-4697-3p	CLIP-seq
MIRT1050067	hsa-miR-4704-3p	CLIP-seq
MIRT1050068	hsa-miR-4720-5p	CLIP-seq
MIRT1050069	hsa-miR-4733-5p	CLIP-seq
MIRT1050070	hsa-miR-4799-3p	CLIP-seq
MIRT1050071	hsa-miR-493	CLIP-seq
MIRT1050072	hsa-miR-499a-5p	CLIP-seq
MIRT1050073	hsa-miR-506	CLIP-seq
MIRT1050074	hsa-miR-522	CLIP-seq
MIRT1050075	hsa-miR-561	CLIP-seq
MIRT1050076	hsa-miR-579	CLIP-seq
MIRT1050077	hsa-miR-613	CLIP-seq
MIRT1050078	hsa-miR-641	CLIP-seq
MIRT1050079	hsa-miR-664	CLIP-seq
MIRT1050080	hsa-miR-98	CLIP-seq
MIRT1050039	hsa-miR-1	CLIP-seq
MIRT2011458	hsa-miR-101	CLIP-seq
MIRT2011459	hsa-miR-1226	CLIP-seq
MIRT2011460	hsa-miR-1238	CLIP-seq
MIRT1050040	hsa-miR-124	CLIP-seq
MIRT2011461	hsa-miR-1284	CLIP-seq
MIRT2011462	hsa-miR-144	CLIP-seq
MIRT1050044	hsa-miR-206	CLIP-seq
MIRT1050046	hsa-miR-3124-3p	CLIP-seq
MIRT2011463	hsa-miR-3158-3p	CLIP-seq
MIRT1050047	hsa-miR-3190	CLIP-seq
MIRT1050050	hsa-miR-3673	CLIP-seq
MIRT2011464	hsa-miR-3689d	CLIP-seq
MIRT1050052	hsa-miR-3714	CLIP-seq
MIRT1050054	hsa-miR-3910	CLIP-seq
MIRT2011465	hsa-miR-4282	CLIP-seq
MIRT2011466	hsa-miR-4446-3p	CLIP-seq
MIRT2011467	hsa-miR-4456	CLIP-seq
MIRT1050059	hsa-miR-4491	CLIP-seq
MIRT2011468	hsa-miR-4492	CLIP-seq
MIRT2011469	hsa-miR-4498	CLIP-seq
MIRT2011470	hsa-miR-4505	CLIP-seq
MIRT1050062	hsa-miR-4642	CLIP-seq
MIRT1050063	hsa-miR-4657	CLIP-seq
MIRT1050064	hsa-miR-4666-5p	CLIP-seq
MIRT1050067	hsa-miR-4704-3p	CLIP-seq
MIRT1050068	hsa-miR-4720-5p	CLIP-seq
MIRT2011471	hsa-miR-4795-3p	CLIP-seq
MIRT1050070	hsa-miR-4799-3p	CLIP-seq
MIRT1050073	hsa-miR-506	CLIP-seq
MIRT2011472	hsa-miR-513a-3p	CLIP-seq
MIRT1050075	hsa-miR-561	CLIP-seq
MIRT2011473	hsa-miR-570	CLIP-seq
MIRT2011474	hsa-miR-607	CLIP-seq
MIRT1050077	hsa-miR-613	CLIP-seq
MIRT2011475	hsa-miR-629	CLIP-seq
MIRT2011476	hsa-miR-665	CLIP-seq
MIRT2011477	hsa-miR-762	CLIP-seq
MIRT1050031	hsa-let-7a	CLIP-seq
MIRT1050032	hsa-let-7b	CLIP-seq
MIRT1050033	hsa-let-7c	CLIP-seq
MIRT1050034	hsa-let-7d	CLIP-seq
MIRT1050035	hsa-let-7e	CLIP-seq
MIRT1050036	hsa-let-7f	CLIP-seq
MIRT1050037	hsa-let-7g	CLIP-seq
MIRT1050038	hsa-let-7i	CLIP-seq
MIRT1050039	hsa-miR-1	CLIP-seq
MIRT2011458	hsa-miR-101	CLIP-seq
MIRT2243660	hsa-miR-10a	CLIP-seq
MIRT2243661	hsa-miR-10b	CLIP-seq
MIRT2243662	hsa-miR-1224-5p	CLIP-seq
MIRT2011460	hsa-miR-1238	CLIP-seq
MIRT2243663	hsa-miR-1244	CLIP-seq
MIRT2243664	hsa-miR-1252	CLIP-seq
MIRT2011461	hsa-miR-1284	CLIP-seq
MIRT2243665	hsa-miR-1294	CLIP-seq
MIRT1050041	hsa-miR-1304	CLIP-seq
MIRT2243666	hsa-miR-132	CLIP-seq
MIRT2243667	hsa-miR-138	CLIP-seq
MIRT2243668	hsa-miR-140-3p	CLIP-seq
MIRT2011462	hsa-miR-144	CLIP-seq
MIRT2243669	hsa-miR-15a	CLIP-seq
MIRT2243670	hsa-miR-15b	CLIP-seq
MIRT2243671	hsa-miR-16	CLIP-seq
MIRT1050042	hsa-miR-186	CLIP-seq
MIRT2243672	hsa-miR-195	CLIP-seq
MIRT1050043	hsa-miR-202	CLIP-seq
MIRT1050044	hsa-miR-206	CLIP-seq
MIRT2243673	hsa-miR-212	CLIP-seq
MIRT2243674	hsa-miR-2276	CLIP-seq
MIRT2243675	hsa-miR-300	CLIP-seq
MIRT1050046	hsa-miR-3124-3p	CLIP-seq
MIRT2243676	hsa-miR-3177-3p	CLIP-seq
MIRT2243677	hsa-miR-3177-5p	CLIP-seq
MIRT2243678	hsa-miR-323-3p	CLIP-seq
MIRT1050048	hsa-miR-337-3p	CLIP-seq
MIRT1050049	hsa-miR-3617	CLIP-seq
MIRT2243679	hsa-miR-3662	CLIP-seq
MIRT2243680	hsa-miR-3671	CLIP-seq
MIRT1050050	hsa-miR-3673	CLIP-seq
MIRT1050051	hsa-miR-3685	CLIP-seq
MIRT2243681	hsa-miR-381	CLIP-seq
MIRT1050053	hsa-miR-384	CLIP-seq
MIRT2243682	hsa-miR-424	CLIP-seq
MIRT2011465	hsa-miR-4282	CLIP-seq
MIRT2243683	hsa-miR-4316	CLIP-seq
MIRT2243684	hsa-miR-4452	CLIP-seq
MIRT2011467	hsa-miR-4456	CLIP-seq
MIRT1050058	hsa-miR-4458	CLIP-seq
MIRT1050061	hsa-miR-4500	CLIP-seq
MIRT1050062	hsa-miR-4642	CLIP-seq
MIRT2243685	hsa-miR-4643	CLIP-seq
MIRT2243686	hsa-miR-4666-3p	CLIP-seq
MIRT2243687	hsa-miR-4667-3p	CLIP-seq
MIRT1050067	hsa-miR-4704-3p	CLIP-seq
MIRT2243688	hsa-miR-4709-5p	CLIP-seq
MIRT1050068	hsa-miR-4720-5p	CLIP-seq
MIRT1050069	hsa-miR-4733-5p	CLIP-seq
MIRT2243689	hsa-miR-4742-3p	CLIP-seq
MIRT2243690	hsa-miR-4749-3p	CLIP-seq
MIRT2243691	hsa-miR-4751	CLIP-seq
MIRT2243692	hsa-miR-4768-3p	CLIP-seq
MIRT2243693	hsa-miR-4772-3p	CLIP-seq
MIRT2243694	hsa-miR-4789-5p	CLIP-seq
MIRT2011471	hsa-miR-4795-3p	CLIP-seq
MIRT1050070	hsa-miR-4799-3p	CLIP-seq
MIRT2243695	hsa-miR-495	CLIP-seq
MIRT2243696	hsa-miR-497	CLIP-seq
MIRT2011472	hsa-miR-513a-3p	CLIP-seq
MIRT2011473	hsa-miR-570	CLIP-seq
MIRT1050076	hsa-miR-579	CLIP-seq
MIRT2243697	hsa-miR-582-5p	CLIP-seq
MIRT2011474	hsa-miR-607	CLIP-seq
MIRT1050077	hsa-miR-613	CLIP-seq
MIRT2011475	hsa-miR-629	CLIP-seq
MIRT2243698	hsa-miR-630	CLIP-seq
MIRT1050078	hsa-miR-641	CLIP-seq
MIRT1050079	hsa-miR-664	CLIP-seq
MIRT1050080	hsa-miR-98	CLIP-seq
MIRT2451277	hsa-miR-548c-3p	CLIP-seq
MIRT1050031	hsa-let-7a	CLIP-seq
MIRT1050032	hsa-let-7b	CLIP-seq
MIRT1050033	hsa-let-7c	CLIP-seq
MIRT1050034	hsa-let-7d	CLIP-seq
MIRT1050035	hsa-let-7e	CLIP-seq
MIRT1050036	hsa-let-7f	CLIP-seq
MIRT1050037	hsa-let-7g	CLIP-seq
MIRT1050038	hsa-let-7i	CLIP-seq
MIRT2011459	hsa-miR-1226	CLIP-seq
MIRT2546873	hsa-miR-1265	CLIP-seq
MIRT1050041	hsa-miR-1304	CLIP-seq
MIRT2243667	hsa-miR-138	CLIP-seq
MIRT1050043	hsa-miR-202	CLIP-seq
MIRT2546874	hsa-miR-2392	CLIP-seq
MIRT2546875	hsa-miR-3121-3p	CLIP-seq
MIRT2546876	hsa-miR-3165	CLIP-seq
MIRT2546877	hsa-miR-3182	CLIP-seq
MIRT2546878	hsa-miR-3188	CLIP-seq
MIRT2546879	hsa-miR-3612	CLIP-seq
MIRT2243679	hsa-miR-3662	CLIP-seq
MIRT2546880	hsa-miR-3668	CLIP-seq
MIRT2011464	hsa-miR-3689d	CLIP-seq
MIRT2546881	hsa-miR-3692	CLIP-seq
MIRT2546882	hsa-miR-3935	CLIP-seq
MIRT2546883	hsa-miR-4314	CLIP-seq
MIRT2546884	hsa-miR-4443	CLIP-seq
MIRT2011467	hsa-miR-4456	CLIP-seq
MIRT1050058	hsa-miR-4458	CLIP-seq
MIRT2546885	hsa-miR-4477a	CLIP-seq
MIRT1050061	hsa-miR-4500	CLIP-seq
MIRT2546886	hsa-miR-4652-3p	CLIP-seq
MIRT2546887	hsa-miR-4727-5p	CLIP-seq
MIRT2243689	hsa-miR-4742-3p	CLIP-seq
MIRT2546888	hsa-miR-4744	CLIP-seq
MIRT2546889	hsa-miR-4762-5p	CLIP-seq
MIRT2546890	hsa-miR-4802-5p	CLIP-seq
MIRT1050076	hsa-miR-579	CLIP-seq
MIRT2546891	hsa-miR-634	CLIP-seq
MIRT2546892	hsa-miR-650	CLIP-seq
MIRT1050079	hsa-miR-664	CLIP-seq
MIRT1050080	hsa-miR-98	CLIP-seq
MIRT1050039	hsa-miR-1	CLIP-seq
MIRT2011458	hsa-miR-101	CLIP-seq
MIRT2011459	hsa-miR-1226	CLIP-seq
MIRT2682350	hsa-miR-1256	CLIP-seq
MIRT2011461	hsa-miR-1284	CLIP-seq
MIRT2011462	hsa-miR-144	CLIP-seq
MIRT1050044	hsa-miR-206	CLIP-seq
MIRT2682351	hsa-miR-2277-3p	CLIP-seq
MIRT1050050	hsa-miR-3673	CLIP-seq
MIRT2011464	hsa-miR-3689d	CLIP-seq
MIRT2546883	hsa-miR-4314	CLIP-seq
MIRT2011467	hsa-miR-4456	CLIP-seq
MIRT2546887	hsa-miR-4727-5p	CLIP-seq
MIRT2546888	hsa-miR-4744	CLIP-seq
MIRT2546890	hsa-miR-4802-5p	CLIP-seq
MIRT2682352	hsa-miR-582-3p	CLIP-seq
MIRT1050077	hsa-miR-613	CLIP-seq
MIRT2546891	hsa-miR-634	CLIP-seq

Transcription factors

Transcription factor	Regulation	Reference
SRF	Unknown	20511232
SRF	Unknown	20511232

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003677	Function	DNA binding	IEA
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005634	Component	Nucleus	IEA
GO:0008333	Process	Endosome to lysosome transport	NAS	10329004
GO:0016055	Process	Wnt signaling pathway	IEA
GO:0016589	Component	NURF complex	IDA	20850016
GO:0030178	Process	Negative regulation of Wnt signaling pathway	ISS
GO:0042802	Function	Identical protein binding	IPI	32296183

Other IDs

• MIM: 604702
• HGNC: 5003
• e!Ensembl: ENSG00000100281

Protein

• UniProt ID: Q9UGU5
• Protein name: HMG domain-containing protein 4 (HMG box-containing protein 4) (High mobility group protein 2-like 1) (Protein HMGBCG)
• Protein function: Negatively regulates Wnt/beta-catenin signaling during development.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF13775	DUF4171	107 → 232	Domain of unknown function (DUF4171)	Domain
  PF00505	HMG_box	407 → 473	HMG (high mobility group) box	Domain

• Sequence:

  MAYDDSVKKEDCFDGDHTFEDIGLAAGRSQREKKRSYKDFLREEEEIAAQVRNSSKKKLK
  DSELYFLGTDTHKKKRKHSSDDYYYGDISSLESSQKKKKKSSPQSTDTAMDLLKAITSPL
  AAGSKPSKKTGEKSSGSSSHSESKKEHHRKKVSGSSGELPLEDGGSHKSKKMKPLYVNTE
  TLTLREPDGLKMKLILSPKEKGSSSVDEESFQYPSQQATVKKSSKKSARDEQGALLLGHE
  LQSFLKTARKKHKSSSDAHSSPGPEGCGSDASQFAESHSANLDLSGLEPILVESDSSSGG
  ELEAGELVIDDSYREIKKKKKSKKSKKKKDKEKHKEKRHSKSKRSLGLSAVPVGEVTVTS
  GPPPSIPYAGAAAPPLPLPGLHTDGHSEKKKKKEEKDKERERGEKPKKKNMSAYQVFCKE
  YRVTIVADHPGIDFGELSKKLAEVWKQLPEKDKLIWKQKAQYLQHKQNKAEATTVKRKAS
  SSEGSMKVKASSVGVLSPQKKSPPTTMLLPASPAKAPETEPIDVAAHLQLLGESLSLIGH
  RLQETEGMVAVSGSLSVLLDSIICALGPLACLTTQLPELNGCPKQVLSNTLDNIAYIMPG
  L

• Sequence length: 601

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
BIPOLAR DISORDER	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MAJOR AFFECTIVE DISORDER 2	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Bipolar Disorder	Bipolar Disorder	BEFREE	17671966		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Bipolar Disorder	Bipolar Disorder	PSYGENET_DG	17671966		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MAJOR AFFECTIVE DISORDER 1	Major Affective Disorder	BEFREE	17671966		★☆☆☆☆ Found in Text Mining only
MAJOR AFFECTIVE DISORDER 2	Major Affective Disorder	BEFREE	17671966		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MAJOR AFFECTIVE DISORDER 2	Major Affective Disorder	PSYGENET_DG	17671966		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MAJOR AFFECTIVE DISORDER 4	Major Affective Disorder	BEFREE	17671966		★☆☆☆☆ Found in Text Mining only
MAJOR AFFECTIVE DISORDER 6	Major Affective Disorder	BEFREE	17671966		★☆☆☆☆ Found in Text Mining only
MAJOR AFFECTIVE DISORDER 7	Major Affective Disorder	BEFREE	17671966		★☆☆☆☆ Found in Text Mining only
MAJOR AFFECTIVE DISORDER 8	Major Affective Disorder	BEFREE	17671966		★☆☆☆☆ Found in Text Mining only
MAJOR AFFECTIVE DISORDER 9	Major Affective Disorder	BEFREE	17671966		★☆☆☆☆ Found in Text Mining only
Primary Myelofibrosis	Myelofibrosis	BEFREE	26547506		★☆☆☆☆ Found in Text Mining only