Gene Gene information from NCBI Gene database.
Entrez ID 100133941
Gene name CD24 molecule
Gene symbol CD24
Synonyms (NCBI Gene)
CD24A
Chromosome 6
Chromosome location 6q21
Summary This gene encodes a sialoglycoprotein that is expressed on mature granulocytes and B cells and modulates growth and differentiation signals to these cells. The precursor protein is cleaved to a short 32 amino acid mature peptide which is anchored via a gl
miRNA miRNA information provided by mirtarbase database.
814
miRTarBase ID miRNA Experiments Reference
MIRT002501 hsa-miR-373-3p Microarray 15685193
MIRT053047 hsa-miR-34a-5p ImmunoblotImmunoprecipitaionLuciferase reporter assayqRT-PCR 23533633
MIRT756302 hsa-miR-181a-3p Luciferase reporter assay 38030594
MIRT874174 hsa-miR-101 CLIP-seq
MIRT874175 hsa-miR-1178 CLIP-seq
Transcription factors Transcription factors information provided by TRRUST V2 database.
1
Transcription factor Regulation Reference
ESR1 Repression 18404683
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
38
GO ID Ontology Definition Evidence Reference
GO:0001666 Process Response to hypoxia IEP 15174142
GO:0001775 Process Cell activation IBA
GO:0001775 Process Cell activation IDA 8223854
GO:0001959 Process Regulation of cytokine-mediated signaling pathway ISS 16390867
GO:0002237 Process Response to molecule of bacterial origin ISS 15493995
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
600074 1645 ENSG00000272398
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
P25063
Protein name Signal transducer CD24 (Small cell lung carcinoma cluster 4 antigen) (CD antigen CD24)
Protein function May have a pivotal role in cell differentiation of different cell types. Signaling could be triggered by the binding of a lectin-like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-ancho
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF14984 CD24 26 79 CD24 protein Family
Tissue specificity TISSUE SPECIFICITY: B-cells. Expressed in a number of B-cell lines including P32/ISH and Namalwa. Expressed in erythroleukemia cell and small cell lung carcinoma cell lines. Also expressed on the surface of T-cells. {ECO:0000269|PubMed:14657362, ECO:00002
Sequence
Sequence length 80
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG 
  Efferocytosis
Hematopoietic cell lineage
 
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
4
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
ALZHEIMER DISEASE GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
LIVER CIRRHOSIS, EXPERIMENTAL CTD
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
MULTIPLE SCLEROSIS Disgenet
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
PANCREATIC NEOPLASMS CTD
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Associations from Text Mining Disease associations identified through text mining
Disease Name Disease (Merged) Source PMID Relationship Type Evidence Score
Acute Erythroblastic Leukemia Erythroblastic Leukemia BEFREE 7736776
★☆☆☆☆
Found in Text Mining only
Acute Kidney Tubular Necrosis Renal tubular necrosis BEFREE 27871857
★☆☆☆☆
Found in Text Mining only
Acute leukemia Leukemia BEFREE 1375695
★☆☆☆☆
Found in Text Mining only
Acute pancreatitis Pancreatitis BEFREE 27203385
★☆☆☆☆
Found in Text Mining only
Adenocarcinoma Adenocarcinoma BEFREE 23679566, 24367507, 28369074
★☆☆☆☆
Found in Text Mining only
Adenocarcinoma of colon Adenocarcinoma Of Colon BEFREE 23331188
★☆☆☆☆
Found in Text Mining only
Adenocarcinoma Of Esophagus Esophageal Cancer BEFREE 28611669
★☆☆☆☆
Found in Text Mining only
Adenocarcinoma of lung (disorder) Lung adenocarcinoma BEFREE 24363164, 29845249
★☆☆☆☆
Found in Text Mining only
Adenocarcinoma, Endometrioid Endometrial Cancer BEFREE 26227486
★☆☆☆☆
Found in Text Mining only
Adenoma Adenoma BEFREE 26078485, 26867566
★☆☆☆☆
Found in Text Mining only