Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	100132386
Gene name	Keratin associated protein 4-9
Gene symbol	KRTAP4-9
Synonyms (NCBI Gene)	KAP4.9
Chromosome	17
Chromosome location	17q21.2

204

Show/Hide all (204)

miRTarBase ID	miRNA	Experiments	Reference
MIRT717042	hsa-miR-602	HITS-CLIP	19536157
MIRT717041	hsa-miR-1539	HITS-CLIP	19536157
MIRT717040	hsa-miR-3193	HITS-CLIP	19536157
MIRT717039	hsa-miR-3140-3p	HITS-CLIP	19536157
MIRT717038	hsa-miR-3074-5p	HITS-CLIP	19536157
MIRT717037	hsa-miR-7152-5p	HITS-CLIP	19536157
MIRT717036	hsa-miR-1237-3p	HITS-CLIP	19536157
MIRT717035	hsa-miR-1248	HITS-CLIP	19536157
MIRT717034	hsa-miR-6515-3p	HITS-CLIP	19536157
MIRT717033	hsa-miR-1236-3p	HITS-CLIP	19536157
MIRT717032	hsa-miR-3124-3p	HITS-CLIP	19536157
MIRT625632	hsa-miR-627-3p	HITS-CLIP	19536157
MIRT717031	hsa-miR-6868-3p	HITS-CLIP	19536157
MIRT717030	hsa-miR-4799-5p	HITS-CLIP	19536157
MIRT717029	hsa-miR-4753-3p	HITS-CLIP	19536157
MIRT717028	hsa-miR-4768-5p	HITS-CLIP	19536157
MIRT717027	hsa-miR-6833-3p	HITS-CLIP	19536157
MIRT717026	hsa-miR-6809-3p	HITS-CLIP	19536157
MIRT610096	hsa-miR-8485	HITS-CLIP	23824327
MIRT610095	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610094	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610093	hsa-miR-603	HITS-CLIP	23824327
MIRT610092	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610091	hsa-miR-8064	HITS-CLIP	23824327
MIRT610090	hsa-miR-3941	HITS-CLIP	23824327
MIRT628645	hsa-miR-4789-5p	HITS-CLIP	23824327
MIRT625631	hsa-miR-4327	HITS-CLIP	23824327
MIRT625630	hsa-miR-1273e	HITS-CLIP	23824327
MIRT625629	hsa-miR-578	HITS-CLIP	23824327
MIRT625629	hsa-miR-578	HITS-CLIP	23824327
MIRT625632	hsa-miR-627-3p	HITS-CLIP	23824327
MIRT625629	hsa-miR-578	HITS-CLIP	23824327
MIRT610096	hsa-miR-8485	HITS-CLIP	23824327
MIRT610095	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610094	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610093	hsa-miR-603	HITS-CLIP	23824327
MIRT610092	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT637072	hsa-miR-4643	HITS-CLIP	23824327
MIRT610091	hsa-miR-8064	HITS-CLIP	23824327
MIRT610090	hsa-miR-3941	HITS-CLIP	23824327
MIRT625632	hsa-miR-627-3p	HITS-CLIP	23824327
MIRT625630	hsa-miR-1273e	HITS-CLIP	23824327
MIRT625629	hsa-miR-578	HITS-CLIP	23824327
MIRT610096	hsa-miR-8485	HITS-CLIP	23824327
MIRT610095	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610094	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610093	hsa-miR-603	HITS-CLIP	23824327
MIRT610092	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610090	hsa-miR-3941	HITS-CLIP	23824327
MIRT628645	hsa-miR-4789-5p	HITS-CLIP	23824327
MIRT610096	hsa-miR-8485	HITS-CLIP	23824327
MIRT610095	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610094	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610093	hsa-miR-603	HITS-CLIP	23824327
MIRT610092	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610090	hsa-miR-3941	HITS-CLIP	23824327
MIRT628645	hsa-miR-4789-5p	HITS-CLIP	23824327
MIRT610096	hsa-miR-8485	HITS-CLIP	23824327
MIRT610095	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610094	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610093	hsa-miR-603	HITS-CLIP	23824327
MIRT610092	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610091	hsa-miR-8064	HITS-CLIP	23824327
MIRT610090	hsa-miR-3941	HITS-CLIP	23824327
MIRT625632	hsa-miR-627-3p	HITS-CLIP	23824327
MIRT625631	hsa-miR-4327	HITS-CLIP	23824327
MIRT625630	hsa-miR-1273e	HITS-CLIP	23824327
MIRT625629	hsa-miR-578	HITS-CLIP	23824327
MIRT618477	hsa-miR-3617-5p	HITS-CLIP	23824327
MIRT618476	hsa-miR-641	HITS-CLIP	23824327
MIRT610096	hsa-miR-8485	HITS-CLIP	23824327
MIRT610095	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610094	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610093	hsa-miR-603	HITS-CLIP	23824327
MIRT610092	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610091	hsa-miR-8064	HITS-CLIP	23824327
MIRT610090	hsa-miR-3941	HITS-CLIP	23824327
MIRT610096	hsa-miR-8485	HITS-CLIP	23824327
MIRT610095	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610094	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610093	hsa-miR-603	HITS-CLIP	23824327
MIRT610092	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610091	hsa-miR-8064	HITS-CLIP	23824327
MIRT610090	hsa-miR-3941	HITS-CLIP	23824327
MIRT495011	hsa-miR-583	PAR-CLIP	22291592
MIRT495010	hsa-miR-3974	PAR-CLIP	22291592
MIRT495009	hsa-miR-3529-3p	PAR-CLIP	22291592
MIRT495008	hsa-miR-624-3p	PAR-CLIP	22291592
MIRT495007	hsa-miR-330-3p	PAR-CLIP	22291592
MIRT495006	hsa-miR-5003-5p	PAR-CLIP	22291592
MIRT495011	hsa-miR-583	PAR-CLIP	22291592
MIRT495010	hsa-miR-3974	PAR-CLIP	22291592
MIRT495009	hsa-miR-3529-3p	PAR-CLIP	22291592
MIRT495008	hsa-miR-624-3p	PAR-CLIP	22291592
MIRT495007	hsa-miR-330-3p	PAR-CLIP	22291592
MIRT495006	hsa-miR-5003-5p	PAR-CLIP	22291592
MIRT495011	hsa-miR-583	PAR-CLIP	23708386
MIRT495010	hsa-miR-3974	PAR-CLIP	23708386
MIRT495009	hsa-miR-3529-3p	PAR-CLIP	23708386
MIRT495008	hsa-miR-624-3p	PAR-CLIP	23708386
MIRT495007	hsa-miR-330-3p	PAR-CLIP	23708386
MIRT495006	hsa-miR-5003-5p	PAR-CLIP	23708386
MIRT717042	hsa-miR-602	HITS-CLIP	19536157
MIRT717041	hsa-miR-1539	HITS-CLIP	19536157
MIRT717040	hsa-miR-3193	HITS-CLIP	19536157
MIRT717039	hsa-miR-3140-3p	HITS-CLIP	19536157
MIRT717038	hsa-miR-3074-5p	HITS-CLIP	19536157
MIRT717037	hsa-miR-7152-5p	HITS-CLIP	19536157
MIRT717036	hsa-miR-1237-3p	HITS-CLIP	19536157
MIRT717035	hsa-miR-1248	HITS-CLIP	19536157
MIRT717034	hsa-miR-6515-3p	HITS-CLIP	19536157
MIRT717033	hsa-miR-1236-3p	HITS-CLIP	19536157
MIRT717032	hsa-miR-3124-3p	HITS-CLIP	19536157
MIRT625632	hsa-miR-627-3p	HITS-CLIP	19536157
MIRT717031	hsa-miR-6868-3p	HITS-CLIP	19536157
MIRT717030	hsa-miR-4799-5p	HITS-CLIP	19536157
MIRT717029	hsa-miR-4753-3p	HITS-CLIP	19536157
MIRT717028	hsa-miR-4768-5p	HITS-CLIP	19536157
MIRT717027	hsa-miR-6833-3p	HITS-CLIP	19536157
MIRT717026	hsa-miR-6809-3p	HITS-CLIP	19536157
MIRT610096	hsa-miR-8485	HITS-CLIP	23824327
MIRT610095	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610094	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610093	hsa-miR-603	HITS-CLIP	23824327
MIRT610092	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610091	hsa-miR-8064	HITS-CLIP	23824327
MIRT610090	hsa-miR-3941	HITS-CLIP	23824327
MIRT628645	hsa-miR-4789-5p	HITS-CLIP	23824327
MIRT625631	hsa-miR-4327	HITS-CLIP	23824327
MIRT625630	hsa-miR-1273e	HITS-CLIP	23824327
MIRT625629	hsa-miR-578	HITS-CLIP	23824327
MIRT625629	hsa-miR-578	HITS-CLIP	23824327
MIRT625632	hsa-miR-627-3p	HITS-CLIP	23824327
MIRT625629	hsa-miR-578	HITS-CLIP	23824327
MIRT610096	hsa-miR-8485	HITS-CLIP	23824327
MIRT610095	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610094	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610093	hsa-miR-603	HITS-CLIP	23824327
MIRT610092	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT637072	hsa-miR-4643	HITS-CLIP	23824327
MIRT610091	hsa-miR-8064	HITS-CLIP	23824327
MIRT610090	hsa-miR-3941	HITS-CLIP	23824327
MIRT625632	hsa-miR-627-3p	HITS-CLIP	23824327
MIRT625630	hsa-miR-1273e	HITS-CLIP	23824327
MIRT625629	hsa-miR-578	HITS-CLIP	23824327
MIRT610096	hsa-miR-8485	HITS-CLIP	23824327
MIRT610095	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610094	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610093	hsa-miR-603	HITS-CLIP	23824327
MIRT610092	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610090	hsa-miR-3941	HITS-CLIP	23824327
MIRT628645	hsa-miR-4789-5p	HITS-CLIP	23824327
MIRT610096	hsa-miR-8485	HITS-CLIP	23824327
MIRT610095	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610094	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610093	hsa-miR-603	HITS-CLIP	23824327
MIRT610092	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610090	hsa-miR-3941	HITS-CLIP	23824327
MIRT628645	hsa-miR-4789-5p	HITS-CLIP	23824327
MIRT610096	hsa-miR-8485	HITS-CLIP	23824327
MIRT610095	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610094	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610093	hsa-miR-603	HITS-CLIP	23824327
MIRT610092	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610091	hsa-miR-8064	HITS-CLIP	23824327
MIRT610090	hsa-miR-3941	HITS-CLIP	23824327
MIRT625632	hsa-miR-627-3p	HITS-CLIP	23824327
MIRT625631	hsa-miR-4327	HITS-CLIP	23824327
MIRT625630	hsa-miR-1273e	HITS-CLIP	23824327
MIRT625629	hsa-miR-578	HITS-CLIP	23824327
MIRT618477	hsa-miR-3617-5p	HITS-CLIP	23824327
MIRT618476	hsa-miR-641	HITS-CLIP	23824327
MIRT610096	hsa-miR-8485	HITS-CLIP	23824327
MIRT610095	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610094	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610093	hsa-miR-603	HITS-CLIP	23824327
MIRT610092	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610091	hsa-miR-8064	HITS-CLIP	23824327
MIRT610090	hsa-miR-3941	HITS-CLIP	23824327
MIRT610096	hsa-miR-8485	HITS-CLIP	23824327
MIRT610095	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610094	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610093	hsa-miR-603	HITS-CLIP	23824327
MIRT610092	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610091	hsa-miR-8064	HITS-CLIP	23824327
MIRT610090	hsa-miR-3941	HITS-CLIP	23824327
MIRT495011	hsa-miR-583	PAR-CLIP	22291592
MIRT495010	hsa-miR-3974	PAR-CLIP	22291592
MIRT495009	hsa-miR-3529-3p	PAR-CLIP	22291592
MIRT495008	hsa-miR-624-3p	PAR-CLIP	22291592
MIRT495007	hsa-miR-330-3p	PAR-CLIP	22291592
MIRT495006	hsa-miR-5003-5p	PAR-CLIP	22291592
MIRT495011	hsa-miR-583	PAR-CLIP	22291592
MIRT495010	hsa-miR-3974	PAR-CLIP	22291592
MIRT495009	hsa-miR-3529-3p	PAR-CLIP	22291592
MIRT495008	hsa-miR-624-3p	PAR-CLIP	22291592
MIRT495007	hsa-miR-330-3p	PAR-CLIP	22291592
MIRT495006	hsa-miR-5003-5p	PAR-CLIP	22291592
MIRT495011	hsa-miR-583	PAR-CLIP	23708386
MIRT495010	hsa-miR-3974	PAR-CLIP	23708386
MIRT495009	hsa-miR-3529-3p	PAR-CLIP	23708386
MIRT495008	hsa-miR-624-3p	PAR-CLIP	23708386
MIRT495007	hsa-miR-330-3p	PAR-CLIP	23708386
MIRT495006	hsa-miR-5003-5p	PAR-CLIP	23708386

Show/Hide all (6)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005829	Component	Cytosol	IEA
GO:0005829	Component	Cytosol	TAS
GO:0005882	Component	Intermediate filament	IEA
GO:0042633	Process	Hair cycle	IBA
GO:0042633	Process	Hair cycle	IDA	21916889
GO:0045095	Component	Keratin filament	IEA

MIM	HGNC	e!Ensembl
HGNC	N/A	HGNC

Q9BYQ8

Protein name

Keratin-associated protein 4-9 (Keratin-associated protein 4.9) (Ultrahigh sulfur keratin-associated protein 4.9)

Protein function

In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their e

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF01500	Keratin_B2	1 → 140	Keratin, high sulfur B2 protein	Family

Tissue specificity

TISSUE SPECIFICITY: Expressed in the hair follicles. {ECO:0000269|PubMed:15955084}.

Sequence

MVSSCCGSVCSDQGCGQDLCQETCCRPSCCETTCCRTTCCRPSCCVSSCCRPQCCQSVCC
QPTCSRPSCCQTTCCRTTCYRPSCCVSSCCRPQCCQPACCQPTCCRPSCCETTCCHPRCC
ISSCCRPSCCVSSCCKPQCCQSVCCQPNCCRPSCSISSCCRPSCCESSCCRPCCCVRPVC
GRVSCHTTCYRPTCVISSCPRPLCCASSCC

Sequence length

210

Interactions

View interactions

	Reactome
			Keratinization

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (2)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
EBV-positive nodal T- and NK-cell lymphoma	Likely benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
STROKE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

KRTAP4-9 (keratin associated protein 4-9)