C17orf107 (chromosome 17 open reading frame 107)

Gene

• Entrez ID: 100130311
• Gene name: Chromosome 17 open reading frame 107
• Gene symbol: C17orf107
• Synonyms (NCBI Gene): -
• Chromosome: 17
• Chromosome location: 17p13.2

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT835971	hsa-miR-1275	CLIP-seq
MIRT835972	hsa-miR-2277-3p	CLIP-seq
MIRT835973	hsa-miR-24	CLIP-seq
MIRT835974	hsa-miR-3660	CLIP-seq
MIRT835975	hsa-miR-4313	CLIP-seq
MIRT835976	hsa-miR-4525	CLIP-seq
MIRT835977	hsa-miR-4526	CLIP-seq
MIRT835978	hsa-miR-4665-5p	CLIP-seq
MIRT835979	hsa-miR-4723-5p	CLIP-seq
MIRT835980	hsa-miR-625	CLIP-seq
MIRT835981	hsa-miR-635	CLIP-seq
MIRT1947682	hsa-miR-3943	CLIP-seq
MIRT1947683	hsa-miR-4435	CLIP-seq
MIRT1947684	hsa-miR-4455	CLIP-seq
MIRT1947685	hsa-miR-4787-5p	CLIP-seq
MIRT1947686	hsa-miR-644	CLIP-seq
MIRT1947687	hsa-miR-663b	CLIP-seq
MIRT2185661	hsa-miR-1293	CLIP-seq
MIRT2185662	hsa-miR-3622a-5p	CLIP-seq
MIRT2185663	hsa-miR-4423-3p	CLIP-seq
MIRT2185664	hsa-miR-4483	CLIP-seq
MIRT2185665	hsa-miR-4648	CLIP-seq
MIRT2185666	hsa-miR-4651	CLIP-seq
MIRT2185667	hsa-miR-4755-3p	CLIP-seq
MIRT2185668	hsa-miR-541	CLIP-seq
MIRT2185669	hsa-miR-608	CLIP-seq
MIRT2185670	hsa-miR-654-5p	CLIP-seq

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Protein

• UniProt ID: Q6ZR85
• Protein name: Uncharacterized protein C17orf107
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF17688	DUF5536	1 → 186	Family of unknown function (DUF5536)	Family

• Sequence:

  MKGTPSSLDTLMWIYHFHSSTEVALQPPLLSSLELSVAAAHEYLEQRFRELKSLEPPEPK
  MQGMLPAPKPTLGLVLREATASLVSFGTTLLEISALWLQQEARRLDGSAGPAPDGRDPGA
  ALSRVAQAAGQGVRQAGAAVGASARLLVQGAWLCLCGRGLQGSASFLRQSQQQLGLGIPG
  EPVSSGHGVS

• Sequence length: 190

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
ALZHEIMER DISEASE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MYASTHENIC SYNDROME, CONGENITAL, 1B, FAST-CHANNEL	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MYASTHENIC SYNDROME, CONGENITAL, 4A, SLOW-CHANNEL	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MYASTHENIC SYNDROME, CONGENITAL, 4B, FAST-CHANNEL	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MYASTHENIC SYNDROME, CONGENITAL, ASSOCIATED WITH ACETYLCHOLINE RECEPTOR DEFICIENCY	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MYASTHENIC SYNDROME, CONGENITAL, POSTSYNAPTIC SLOW-CHANNEL	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MYASTHENIC SYNDROMES, CONGENITAL	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MYASTHENIC SYNDROMES, CONGENITAL, SLOW CHANNEL	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Hirschsprung Disease	Hirschsprung Disease	BEFREE	30663199		★☆☆☆☆ Found in Text Mining only
MYASTHENIC SYNDROME, CONGENITAL, 1B, FAST-CHANNEL	Myasthenic Syndrome	CLINVAR_DG			★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MYASTHENIC SYNDROME, CONGENITAL, 4A, SLOW-CHANNEL	Myasthenic Syndrome	CLINVAR_DG	14592868, 21822932, 22678886, 27779167, 7538206, 8755487, 8872460, 9158150		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MYASTHENIC SYNDROME, CONGENITAL, 4B, FAST-CHANNEL	Myasthenic Syndrome	CLINVAR_DG			★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MYASTHENIC SYNDROME, CONGENITAL, ASSOCIATED WITH ACETYLCHOLINE RECEPTOR DEFICIENCY	Myasthenic Syndrome	CLINVAR_DG			★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Myasthenic Syndromes, Congenital	Myasthenic Syndrome	CLINVAR_DG	20562457, 21150643, 27717316, 29054425, 29383513, 9158150, 9708546		★★☆☆☆ Found in Text Mining + Unknown/Other Associations