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autosomal dominant polycystic kidney disease
autosomal dominant polycystic kidney disease
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Pathways column key:
KEGG
Reactome
Disease Term
Disease ID
Gene Symbol
Classification
References
Source
Pathways
autosomal dominant polycystic kidney disease
ALG5
Unknown
—
ClinGen
N-Glycan biosynthesis
Metabolic pathways
Synthesis of dolichyl-phosphate-glucose
ALG8
Unknown
—
ClinGen
N-Glycan biosynthesis
Metabolic pathways
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
Defective ALG8 causes ALG8-CDG (CDG-1h)
+1 more
NEK8
Unknown
—
ClinGen
—
All
7
Causal
4
Unknown
3
Select all
Clear
ClinVar
0
Orphanet
0
Disgenet
0
CTD
0
HPO
0
GWAS catalog
0
GenCC
0
ClinGen
3
Related Diseases
Diseases that share the most curated genes with autosomal dominant polycystic kidney disease.
5
View disease cluster →
Anhydramnios
3 shared genes
DNAJB11, PKD1, PKD2
Related via 3 shared genes including DNAJB11, PKD1, PKD2.
Polycystic kidney disease
7 shared genes
ALG8, DNAJB11, PKD1, PKD2, IFT140, ALG5, NEK8
Related via 7 shared genes including ALG8, DNAJB11, PKD1.
Liver cyst
1 shared gene
PKD1
Related via 1 shared gene including PKD1.
IFT140-related recessive ciliopathy
1 shared gene
IFT140
Related via 1 shared gene including IFT140.
renal-hepatic-pancreatic dysplasia 2
1 shared gene
NEK8
Related via 1 shared gene including NEK8.
1
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