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autosomal dominant nonsyndromic hearing loss
autosomal dominant nonsyndromic hearing loss
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Pathways column key:
KEGG
Reactome
Disease Term
Disease ID
Gene Symbol
Classification
References
Source
Pathways
autosomal dominant nonsyndromic hearing loss
ATP2B2
Causal
—
ClinGen
Calcium signaling pathway
cGMP-PKG signaling pathway
cAMP signaling pathway
Adrenergic signaling in cardiomyocytes
Aldosterone synthesis and secretion
Endocrine and other factor-regulated calcium reabsorption
Salivary secretion
Pancreatic secretion
Mineral absorption
Reduction of cytosolic Ca++ levels
Ion homeostasis
Ion transport by P-type ATPases
+9 more
PDE1C
Causal
—
ClinGen
Purine metabolism
Metabolic pathways
Calcium signaling pathway
Olfactory transduction
Taste transduction
Renin secretion
Morphine addiction
Cam-PDE 1 activation
+5 more
PLS1
Causal
—
ClinGen
—
All
9
Causal
3
Unknown
6
Select all
Clear
ClinVar
0
Orphanet
0
Disgenet
0
CTD
0
HPO
0
GWAS catalog
0
GenCC
0
ClinGen
3
Related Diseases
Diseases that share the most curated genes with autosomal dominant nonsyndromic hearing loss.
5
View disease cluster →
Nonsyndromic hearing loss
9 shared genes
COL11A1, LMX1A, ATP2B2, RIPOR2, PDE1C, ATP11A, ABCC1, CD164, PLS1
Related via 9 shared genes including COL11A1, LMX1A, ATP2B2.
Isolated sensorineural deafness
9 shared genes
COL11A1, LMX1A, ATP2B2, RIPOR2, PDE1C, ATP11A, ABCC1, CD164, PLS1
Related via 9 shared genes including COL11A1, LMX1A, ATP2B2.
Intervertebral disc displacement
1 shared gene
COL11A1
Related via 1 shared gene including COL11A1.
Congenital hearing disorder
1 shared gene
PLS1
Related via 1 shared gene including PLS1.
Machado-joseph disease
1 shared gene
ATP11A
Related via 1 shared gene including ATP11A.
1
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