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Xfe progeroid syndrome
Xfe progeroid syndrome
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Pathways column key:
KEGG
Reactome
Disease Term
Disease ID
Gene Symbol
Classification
References
Source
Pathways
XFE PROGEROID SYNDROME
610965
C1970416
MESH:C567043
MONDO:0012590
ERCC4
Causal
20301571
CTD
,
ClinVar
,
Disgenet
,
GenCC
,
HPO
Nucleotide excision repair
Fanconi anemia pathway
HDR through Single Strand Annealing (SSA)
Formation of Incision Complex in GG-NER
Dual Incision in GG-NER
Dual incision in TC-NER
Fanconi Anemia Pathway
+4 more
POLE
Unknown
20301571
Disgenet
DNA replication
Base excision repair
Nucleotide excision repair
Recognition of DNA damage by PCNA-containing replication complex
PCNA-Dependent Long Patch Base Excision Repair
Termination of translesion DNA synthesis
HDR through Homologous Recombination (HRR)
Gap-filling DNA repair synthesis and ligation in GG-NER
Dual Incision in GG-NER
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
DNA replication initiation
Activation of the pre-replicative complex
+10 more
All
2
Causal
1
Unknown
1
Select all
Clear
ClinVar
1
Orphanet
0
Disgenet
2
CTD
1
HPO
1
GWAS catalog
0
GenCC
1
ClinGen
0
Related Diseases
Diseases that share the most curated genes with Xfe progeroid syndrome.
5
View disease cluster →
xeroderma pigmentosum group F
1 shared gene
ERCC4
Related via 1 shared gene including ERCC4.
POLE-related polyposis and colorectal cancer syndrome
1 shared gene
POLE
Related via 1 shared gene including POLE.
Colorectal cancer susceptibility
1 shared gene
POLE
Related via 1 shared gene including POLE.
Xeroderma pigmentosum-cockayne syndrome
1 shared gene
ERCC4
Related via 1 shared gene including ERCC4.
Cockayne syndrome
1 shared gene
ERCC4
Related via 1 shared gene including ERCC4.
1
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