Wolff-parkinson-white syndrome

Synaptic vesicle cycle Serotonin Neurotransmitter Release Cycle Norepinephrine Neurotransmitter Release Cycle Glutamate Neurotransmitter Release Cycle Dopamine Neurotransmitter Release Cycle Acetylcholine Neurotransmitter Release Cycle GABA synthesis, release, reuptake and degradation +4 more

Wnt signaling pathway Notch signaling pathway Pathways in cancer Chronic myeloid leukemia Deactivation of the beta-catenin transactivating complex SUMOylation of transcription cofactors Repression of WNT target genes TCF7L2 mutants don't bind CTBP +5 more

ABC transporters ATP sensitive Potassium channels ABC-family proteins mediated transport Ion homeostasis Defective ABCC9 causes dilated cardiomyopathy 10, familial atrial fibrillation 12 and hypertrichotic osteochondrodysplasia +2 more

Cardiac muscle contraction Adrenergic signaling in cardiomyocytes Motor proteins Cytoskeleton in muscle cells Hypertrophic cardiomyopathy Dilated cardiomyopathy Striated Muscle Contraction +4 more

Cytoskeleton in muscle cells Arrhythmogenic right ventricular cardiomyopathy Platelet degranulation Striated Muscle Contraction Unblocking of NMDA receptors, glutamate binding and activation RAF/MAP kinase cascade +3 more

Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Phase 3 - rapid repolarisation Phase 2 - plateau phase Anchoring of the basal body to the plasma membrane Signaling by BRAF and RAF fusions AURKA Activation by TPX2 +7 more

Cytoskeleton in muscle cells Proteoglycans in cancer Interaction between L1 and Ankyrins COPI-mediated anterograde transport +1 more

MAPK signaling pathway Calcium signaling pathway cGMP-PKG signaling pathway cAMP signaling pathway Cardiac muscle contraction Adrenergic signaling in cardiomyocytes Vascular smooth muscle contraction Circadian entrainment Long-term potentiation Retrograde endocannabinoid signaling Glutamatergic synapse Cholinergic synapse Serotonergic synapse GABAergic synapse Dopaminergic synapse Taste transduction Insulin secretion GnRH signaling pathway Oxytocin signaling pathway Renin secretion Aldosterone synthesis and secretion Cortisol synthesis and secretion GnRH secretion Type II diabetes mellitus Cushing syndrome Growth hormone synthesis, secretion and action Alzheimer disease Prion disease Pathways of neurodegeneration - multiple diseases Amphetamine addiction Chemical carcinogenesis - receptor activation Hypertrophic cardiomyopathy Arrhythmogenic right ventricular cardiomyopathy Dilated cardiomyopathy Regulation of insulin secretion Phase 0 - rapid depolarisation Phase 2 - plateau phase +34 more

MAPK signaling pathway Calcium signaling pathway Type II diabetes mellitus Presynaptic depolarization and calcium channel opening Regulation of insulin secretion +2 more

Calcium signaling pathway Cardiac muscle contraction Stimuli-sensing channels Ion homeostasis +1 more

Cytoskeleton in muscle cells Protein digestion and absorption Collagen degradation Extracellular matrix organization Collagen biosynthesis and modifying enzymes Signaling by PDGF Assembly of collagen fibrils and other multimeric structures Integrin cell surface interactions Non-integrin membrane-ECM interactions ECM proteoglycans NCAM1 interactions MET activates PTK2 signaling Collagen chain trimerization +10 more

Cytoskeleton in muscle cells Arrhythmogenic right ventricular cardiomyopathy Apoptotic cleavage of cell adhesion proteins Neutrophil degranulation Keratinization Formation of the cornified envelope +3 more

MAPK signaling pathway Focal adhesion Salmonella infection Proteoglycans in cancer Platelet degranulation GP1b-IX-V activation signalling Cell-extracellular matrix interactions RHO GTPases activate PAKs OAS antiviral response +6 more

Cytoskeleton in muscle cells Cell-extracellular matrix interactions

mTOR signaling pathway Amino acids regulate mTORC1

Gap junction assembly

Glycerophospholipid metabolism Synthesis of PA

Cytoskeleton in muscle cells Pathways in cancer Transcriptional misregulation in cancer Acute myeloid leukemia Gastric cancer Arrhythmogenic right ventricular cardiomyopathy Adherens junctions interactions VEGFR2 mediated vascular permeability Neutrophil degranulation Keratinization Formation of the cornified envelope +8 more

Voltage gated Potassium channels Phase 3 - rapid repolarisation

Cholinergic synapse Oxytocin signaling pathway Renin secretion Gastric acid secretion Activation of G protein gated Potassium channels Classical Kir channels Phase 4 - resting membrane potential Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits +5 more

Adrenergic signaling in cardiomyocytes Cholinergic synapse Gastric acid secretion Pancreatic secretion Protein digestion and absorption Vibrio cholerae infection Voltage gated Potassium channels Phase 3 - rapid repolarisation Phase 2 - plateau phase +6 more

PI3K-Akt signaling pathway Focal adhesion ECM-receptor interaction African trypanosomiasis Toxoplasmosis Amoebiasis Human papillomavirus infection Pathways in cancer Small cell lung cancer Laminin interactions MET activates PTK2 signaling +8 more

PI3K-Akt signaling pathway Focal adhesion ECM-receptor interaction Prion disease Toxoplasmosis Amoebiasis Human papillomavirus infection Pathways in cancer Small cell lung cancer Laminin interactions Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) MET activates PTK2 signaling Post-translational protein phosphorylation +10 more

Apoptosis Cytoskeleton in muscle cells Hypertrophic cardiomyopathy Arrhythmogenic right ventricular cardiomyopathy Dilated cardiomyopathy Nuclear Envelope Breakdown Initiation of Nuclear Envelope (NE) Reformation Breakdown of the nuclear lamina XBP1(S) activates chaperone genes Depolymerisation of the Nuclear Lamina Signaling by BRAF and RAF fusions +8 more

Cytoskeleton in muscle cells Hypertrophic cardiomyopathy Dilated cardiomyopathy Striated Muscle Contraction +1 more

Virion - Lassa virus and SFTS virus Vascular smooth muscle contraction Tight junction Regulation of actin cytoskeleton Motor proteins Cytoskeleton in muscle cells Pathogenic Escherichia coli infection Smooth Muscle Contraction RHO GTPases activate PAKs +6 more

cGMP-PKG signaling pathway Cardiac muscle contraction Adrenergic signaling in cardiomyocytes Motor proteins Cytoskeleton in muscle cells Thyroid hormone signaling pathway Hypertrophic cardiomyopathy Dilated cardiomyopathy Viral myocarditis Striated Muscle Contraction +7 more

cGMP-PKG signaling pathway Cardiac muscle contraction Adrenergic signaling in cardiomyocytes Motor proteins Cytoskeleton in muscle cells Thyroid hormone signaling pathway Hypertrophic cardiomyopathy Dilated cardiomyopathy Viral myocarditis +6 more

Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane RHO GTPases Activate Formins Mitotic Prometaphase AURKA Activation by TPX2 EML4 and NUDC in mitotic spindle formation +10 more

Cytoskeleton in muscle cells

TGF-beta signaling pathway TFAP2 (AP-2) family regulates transcription of other transcription factors

Lysine degradation Metabolic pathways Thermogenesis PKMTs methylate histone lysines +1 more

FoxO signaling pathway AMPK signaling pathway Longevity regulating pathway Longevity regulating pathway - multiple species Apelin signaling pathway Tight junction Circadian rhythm Thermogenesis Insulin signaling pathway Adipocytokine signaling pathway Oxytocin signaling pathway Glucagon signaling pathway Insulin resistance Non-alcoholic fatty liver disease Alcoholic liver disease Hypertrophic cardiomyopathy Macroautophagy AMPK inhibits chREBP transcriptional activation activity Carnitine metabolism Energy dependent regulation of mTOR by LKB1-AMPK TP53 Regulates Metabolic Genes Regulation of TP53 Activity through Phosphorylation +19 more

TNF signaling pathway

Calcium signaling pathway cAMP signaling pathway Cardiac muscle contraction Adrenergic signaling in cardiomyocytes Apelin signaling pathway Circadian entrainment Insulin secretion Oxytocin signaling pathway Pancreatic secretion Prion disease Pathways of neurodegeneration - multiple diseases Hypertrophic cardiomyopathy Arrhythmogenic right ventricular cardiomyopathy Dilated cardiomyopathy Diabetic cardiomyopathy Stimuli-sensing channels Ion homeostasis +14 more

Adrenergic signaling in cardiomyocytes Phase 0 - rapid depolarisation

Thyroid hormone synthesis Multifunctional anion exchangers Defective SLC26A4 causes Pendred syndrome (PDS)

Cytoskeleton in muscle cells Hypertrophic cardiomyopathy Arrhythmogenic right ventricular cardiomyopathy Dilated cardiomyopathy Viral myocarditis +2 more

YAP1- and WWTR1 (TAZ)-stimulated gene expression Physiological factors

Cytoskeleton in muscle cells Striated Muscle Contraction

MAPK signaling pathway Cytokine-cytokine receptor interaction FoxO signaling pathway Endocytosis Cellular senescence TGF-beta signaling pathway Osteoclast differentiation Hippo signaling pathway Adherens junction Th17 cell differentiation Relaxin signaling pathway AGE-RAGE signaling pathway in diabetic complications Chagas disease Hepatitis B Human T-cell leukemia virus 1 infection Pathways in cancer Transcriptional misregulation in cancer Colorectal cancer Pancreatic cancer Chronic myeloid leukemia Hepatocellular carcinoma Gastric cancer Diabetic cardiomyopathy Downregulation of TGF-beta receptor signaling TGF-beta receptor signaling activates SMADs TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) SMAD2/3 Phosphorylation Motif Mutants in Cancer TGFBR2 MSI Frameshift Mutants in Cancer TGFBR2 Kinase Domain Mutants in Cancer TGFBR1 KD Mutants in Cancer TGFBR1 LBD Mutants in Cancer +28 more

Cardiac muscle contraction Adrenergic signaling in cardiomyocytes Motor proteins Cytoskeleton in muscle cells Hypertrophic cardiomyopathy Dilated cardiomyopathy Striated Muscle Contraction +4 more

Insulin secretion TRP channels

Cytoskeleton in muscle cells Hypertrophic cardiomyopathy Dilated cardiomyopathy Platelet degranulation Striated Muscle Contraction +2 more

Focal adhesion Adherens junction Leukocyte transendothelial migration Regulation of actin cytoskeleton Cytoskeleton in muscle cells Bacterial invasion of epithelial cells Shigellosis Amoebiasis Platelet degranulation Smooth Muscle Contraction MAP2K and MAPK activation Neutrophil degranulation Signaling by moderate kinase activity BRAF mutants Signaling by high-kinase activity BRAF mutants Signaling by BRAF and RAF fusions Paradoxical activation of RAF signaling by kinase inactive BRAF Signaling downstream of RAS mutants +14 more