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Weyers acrofacial dysostosis
Weyers acrofacial dysostosis
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Pathways column key:
KEGG
Reactome
Disease Term
Disease ID
Gene Symbol
Classification
References
Source
Pathways
WEYERS ACROFACIAL DYSOSTOSIS
C0457013
193530
MESH:C536695
CTNNB1
Unknown
28813576
Disgenet
Rap1 signaling pathway
Wnt signaling pathway
Hippo signaling pathway
Focal adhesion
Adherens junction
Signaling pathways regulating pluripotency of stem cells
Leukocyte transendothelial migration
Melanogenesis
Thyroid hormone signaling pathway
Cushing syndrome
Alcoholic liver disease
Alzheimer disease
Pathways of neurodegeneration - multiple diseases
Bacterial invasion of epithelial cells
Salmonella infection
Hepatitis C
Human cytomegalovirus infection
Human papillomavirus infection
Kaposi sarcoma-associated herpesvirus infection
Pathways in cancer
Proteoglycans in cancer
Colorectal cancer
Endometrial cancer
Prostate cancer
Thyroid cancer
Basal cell carcinoma
Breast cancer
Hepatocellular carcinoma
Gastric cancer
Arrhythmogenic right ventricular cardiomyopathy
Fluid shear stress and atherosclerosis
Degradation of beta-catenin by the destruction complex
Beta-catenin phosphorylation cascade
TCF dependent signaling in response to WNT
Formation of the beta-catenin:TCF transactivating complex
LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production
Apoptotic cleavage of cell adhesion proteins
Deactivation of the beta-catenin transactivating complex
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)
Ca2+ pathway
Adherens junctions interactions
Binding of TCF/LEF:CTNNB1 to target gene promoters
Disassembly of the destruction complex and recruitment of AXIN to the membrane
VEGFR2 mediated vascular permeability
Myogenesis
Misspliced GSK3beta mutants stabilize beta-catenin
S33 mutants of beta-catenin aren't phosphorylated
S37 mutants of beta-catenin aren't phosphorylated
S45 mutants of beta-catenin aren't phosphorylated
T41 mutants of beta-catenin aren't phosphorylated
RHO GTPases activate IQGAPs
Transcriptional Regulation by VENTX
InlA-mediated entry of Listeria monocytogenes into host cells
RUNX3 regulates WNT signaling
+51 more
EVC
Unknown
26691988
CTD
,
Disgenet
,
HPO
Hedgehog signaling pathway
Hedgehog 'on' state
Activation of SMO
EVC2
Unknown
26691988
CTD
,
Disgenet
,
HPO
Hedgehog signaling pathway
Hedgehog 'on' state
Activation of SMO
All
3
Causal
0
Unknown
3
Select all
Clear
ClinVar
0
Orphanet
0
Disgenet
3
CTD
2
HPO
2
GWAS catalog
0
GenCC
0
ClinGen
0
Related Diseases
Diseases that share the most curated genes with Weyers acrofacial dysostosis.
5
View disease cluster →
Curry-hall syndrome
2 shared genes
EVC, EVC2
Related via 2 shared genes including EVC, EVC2.
Acrofacial dysostosis
2 shared genes
EVC, EVC2
Related via 2 shared genes including EVC, EVC2.
Intellectual developmental disorder dysmorphic ocular microcephaly peripheral
1 shared gene
CTNNB1
Related via 1 shared gene including CTNNB1.
CTNNB1-related neurodevelopmental disorder and/or vitreoretinopathy
1 shared gene
CTNNB1
Related via 1 shared gene including CTNNB1.
Craniopharyngioma
1 shared gene
CTNNB1
Related via 1 shared gene including CTNNB1.
1
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