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Uveal melanoma
Uveal melanoma
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Pathways column key:
KEGG
Reactome
Disease Term
Disease ID
Gene Symbol
Classification
References
Source
Pathways
UVEAL MELANOMA
39044
MESH:D000098943
BAP1
Causal
21051595
21874000
25231345
26719535
21941004
CTD
,
Orphanet
Polycomb repressive complex
UCH proteinases
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
MBD4
Causal
29760383
32239153
30049810
CTD
,
ClinGen
Base excision repair
Recognition and association of DNA glycosylase with site containing an affected pyrimidine
Cleavage of the damaged pyrimidine
Displacement of DNA glycosylase by APEX1
+1 more
PLCB4
Causal
27089179
CTD
Inositol phosphate metabolism
Metabolic pathways
Rap1 signaling pathway
Calcium signaling pathway
cGMP-PKG signaling pathway
Chemokine signaling pathway
Phosphatidylinositol signaling system
Sphingolipid signaling pathway
Phospholipase D signaling pathway
Hormone signaling
Adrenergic signaling in cardiomyocytes
Vascular smooth muscle contraction
Wnt signaling pathway
Apelin signaling pathway
Gap junction
Platelet activation
Neutrophil extracellular trap formation
NOD-like receptor signaling pathway
Circadian entrainment
Long-term potentiation
Retrograde endocannabinoid signaling
Glutamatergic synapse
Cholinergic synapse
Serotonergic synapse
Dopaminergic synapse
Long-term depression
Taste transduction
Inflammatory mediator regulation of TRP channels
Insulin secretion
GnRH signaling pathway
Estrogen signaling pathway
Melanogenesis
Thyroid hormone synthesis
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Glucagon signaling pathway
Renin secretion
Aldosterone synthesis and secretion
Relaxin signaling pathway
Cortisol synthesis and secretion
Parathyroid hormone synthesis, secretion and action
GnRH secretion
AGE-RAGE signaling pathway in diabetic complications
Cushing syndrome
Growth hormone synthesis, secretion and action
Endocrine and other factor-regulated calcium reabsorption
Salivary secretion
Gastric acid secretion
Pancreatic secretion
Carbohydrate digestion and absorption
Alzheimer disease
Huntington disease
Spinocerebellar ataxia
Pathways of neurodegeneration - multiple diseases
Shigellosis
Chagas disease
African trypanosomiasis
Amoebiasis
Human cytomegalovirus infection
Pathways in cancer
Diabetic cardiomyopathy
Lipid and atherosclerosis
PLC beta mediated events
Synthesis of IP3 and IP4 in the cytosol
G alpha (q) signalling events
+62 more
All
40
Causal
3
Unknown
37
Select all
Clear
ClinVar
0
Orphanet
1
Disgenet
0
CTD
3
HPO
0
GWAS catalog
0
GenCC
0
ClinGen
1
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3 shared genes
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Related via 3 shared genes including HERC2, OCA2, IRF4.
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Related via 4 shared genes including HERC2, IRF4, SGPL1.
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2 shared genes
GNA11, GNAQ
Related via 2 shared genes including GNA11, GNAQ.
Cutis marmorata telangiectatica congenita
2 shared genes
GNA11, ARL6IP6
Related via 2 shared genes including GNA11, ARL6IP6.
1
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