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Ureter urothelial carcinoma
Ureter urothelial carcinoma
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Pathways column key:
KEGG
Reactome
Disease Term
Disease ID
Gene Symbol
Classification
References
Source
Pathways
ureter urothelial carcinoma
EFO_1001973
FGFR3
Unknown
27029078
17579624
21547910
Open Targets
EGFR tyrosine kinase inhibitor resistance
MAPK signaling pathway
Ras signaling pathway
Rap1 signaling pathway
Calcium signaling pathway
Endocytosis
PI3K-Akt signaling pathway
Signaling pathways regulating pluripotency of stem cells
Regulation of actin cytoskeleton
Pathways in cancer
MicroRNAs in cancer
Bladder cancer
Central carbon metabolism in cancer
PI3K Cascade
PIP3 activates AKT signaling
Signaling by activated point mutants of FGFR3
FGFR3b ligand binding and activation
FGFR3c ligand binding and activation
FGFR3 mutant receptor activation
t(4;14) translocations of FGFR3
Constitutive Signaling by Aberrant PI3K in Cancer
Phospholipase C-mediated cascade; FGFR3
SHC-mediated cascade:FGFR3
FRS-mediated FGFR3 signaling
PI-3K cascade:FGFR3
Negative regulation of FGFR3 signaling
RAF/MAP kinase cascade
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
Signaling by FGFR3 fusions in cancer
Signaling by FGFR3 point mutants in cancer
+27 more
SMARCB1
Unknown
28974397
Open Targets
ATP-dependent chromatin remodeling
Viral life cycle - HIV-1
Thermogenesis
Hepatocellular carcinoma
RMTs methylate histone arginines
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
+3 more
STK11
Unknown
32636318
Open Targets
FoxO signaling pathway
Hormone signaling
Autophagy - animal
mTOR signaling pathway
PI3K-Akt signaling pathway
AMPK signaling pathway
Longevity regulating pathway
Tight junction
Adipocytokine signaling pathway
Energy dependent regulation of mTOR by LKB1-AMPK
Regulation of TP53 Activity through Phosphorylation
FOXO-mediated transcription of cell death genes
+9 more
TP53
Unknown
8109252
7591300
Open Targets
Endocrine resistance
Platinum drug resistance
MAPK signaling pathway
Sphingolipid signaling pathway
Cell cycle
p53 signaling pathway
Mitophagy - animal
PI3K-Akt signaling pathway
Apoptosis
Longevity regulating pathway
Ferroptosis
Cellular senescence
Wnt signaling pathway
Neurotrophin signaling pathway
Thyroid hormone signaling pathway
Parkinson disease
Amyotrophic lateral sclerosis
Huntington disease
Shigellosis
Hepatitis C
Hepatitis B
Measles
Human cytomegalovirus infection
Human papillomavirus infection
Human T-cell leukemia virus 1 infection
Kaposi sarcoma-associated herpesvirus infection
Herpes simplex virus 1 infection
Epstein-Barr virus infection
Pathways in cancer
Transcriptional misregulation in cancer
Viral carcinogenesis
Proteoglycans in cancer
MicroRNAs in cancer
Colorectal cancer
Pancreatic cancer
Endometrial cancer
Glioma
Prostate cancer
Thyroid cancer
Basal cell carcinoma
Melanoma
Bladder cancer
Chronic myeloid leukemia
Small cell lung cancer
Non-small cell lung cancer
Breast cancer
Hepatocellular carcinoma
Gastric cancer
Central carbon metabolism in cancer
Lipid and atherosclerosis
Fluid shear stress and atherosclerosis
Activation of NOXA and translocation to mitochondria
Activation of PUMA and translocation to mitochondria
Pre-NOTCH Transcription and Translation
Oxidative Stress Induced Senescence
Formation of Senescence-Associated Heterochromatin Foci (SAHF)
Oncogene Induced Senescence
DNA Damage/Telomere Stress Induced Senescence
SUMOylation of transcription factors
Autodegradation of the E3 ubiquitin ligase COP1
TP53 Regulates Metabolic Genes
Ub-specific processing proteases
Ovarian tumor domain proteases
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
Interleukin-4 and Interleukin-13 signaling
TP53 Regulates Transcription of DNA Repair Genes
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain
TP53 Regulates Transcription of Caspase Activators and Caspases
TP53 Regulates Transcription of Death Receptors and Ligands
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest
Regulation of TP53 Expression
Regulation of TP53 Activity through Phosphorylation
Regulation of TP53 Degradation
Regulation of TP53 Activity through Acetylation
Regulation of TP53 Activity through Association with Co-factors
Regulation of TP53 Activity through Methylation
PI5P Regulates TP53 Acetylation
G2/M DNA damage checkpoint
G2/M Checkpoints
Stabilization of p53
Transcriptional activation of cell cycle inhibitor p21
The role of GTSE1 in G2/M progression after G2 checkpoint
Transcriptional Regulation by VENTX
RUNX3 regulates CDKN1A transcription
Regulation of PTEN gene transcription
+85 more
All
4
Causal
0
Unknown
4
Select all
Clear
ClinVar
0
Orphanet
0
Disgenet
0
CTD
0
HPO
0
GWAS catalog
0
GenCC
0
ClinGen
0
Open Targets
4
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Related via 1 shared gene including FGFR3.
1
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