Tourette syndrome

Phase I - Functionalization of compounds

Defective B3GALTL causes Peters-plus syndrome (PpS) O-glycosylation of TSR domain-containing proteins

Glycerolipid metabolism Glycerophospholipid metabolism Metabolic pathways Phospholipase D signaling pathway Synthesis of PA +2 more

Cytoskeleton in muscle cells Proteoglycans in cancer Interaction between L1 and Ankyrins COPI-mediated anterograde transport +1 more

Salmonella infection Neutrophil degranulation

Adherens junction Regulation of actin cytoskeleton Pathogenic Escherichia coli infection Yersinia infection Regulation of actin dynamics for phagocytic cup formation VEGFA-VEGFR2 Pathway RHO GTPases Activate WASPs and WAVEs FCGR3A-mediated phagocytosis +5 more

TP53 Regulates Transcription of DNA Repair Genes

Cytoskeleton in muscle cells Protein digestion and absorption Collagen biosynthesis and modifying enzymes Assembly of collagen fibrils and other multimeric structures MET activates PTK2 signaling Collagen chain trimerization +3 more

Lysine degradation Other types of O-glycan biosynthesis Metabolic pathways Collagen biosynthesis and modifying enzymes +1 more

Oocyte meiosis Progesterone-mediated oocyte maturation

Hedgehog signaling pathway

RAB GEFs exchange GTP for GDP on RABs

Neuroactive ligand-receptor interaction Hormone signaling Dopaminergic synapse Dopamine receptors G alpha (i) signalling events +2 more

Neuroactive ligand-receptor interaction Hormone signaling Dopaminergic synapse Dopamine receptors G alpha (i) signalling events +2 more

Ras signaling pathway Cellular senescence Human T-cell leukemia virus 1 infection Pathways in cancer Renal cell carcinoma Oncogene Induced Senescence +3 more

Formation of the cornified envelope

Neddylation Antigen processing: Ubiquitination & Proteasome degradation

Rap1 signaling pathway Neuroactive ligand-receptor interaction Neutrophil extracellular trap formation Staphylococcus aureus infection G alpha (i) signalling events Formyl peptide receptors bind formyl peptides and many other ligands Interleukin-10 signaling Neutrophil degranulation +5 more

Glycerolipid metabolism Metabolic pathways PPAR signaling pathway Triglyceride biosynthesis +1 more

RHO GTPases regulate CFTR trafficking

cAMP signaling pathway Taste transduction HCN channels

Apelin signaling pathway Neutrophil extracellular trap formation Alcoholism Viral carcinogenesis MicroRNAs in cancer Constitutive Signaling by NOTCH1 PEST Domain Mutants Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants Notch-HLH transcription pathway +5 more

Histidine metabolism Metabolic pathways Histidine catabolism

mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA

Inositol phosphate metabolism Metabolic pathways Calcium signaling pathway Phosphatidylinositol signaling system Synthesis of IP3 and IP4 in the cytosol +2 more

Neddylation Antigen processing: Ubiquitination & Proteasome degradation

HDMs demethylate histones TFAP2 (AP-2) family regulates transcription of cell cycle factors

Ubiquitin mediated proteolysis Neddylation Antigen processing: Ubiquitination & Proteasome degradation

Transport of fatty acids

Hippo signaling pathway Tight junction Human papillomavirus infection

Platelet sensitization by LDL Retinoid metabolism and transport

SLBP independent Processing of Histone Pre-mRNAs RNA Polymerase II Transcription Termination SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs

Neuroactive ligand-receptor interaction

Pyruvate metabolism Carbon metabolism Citric acid cycle (TCA cycle)

Galactose metabolism Starch and sucrose metabolism Metabolic pathways Carbohydrate digestion and absorption Digestion of dietary carbohydrate Neutrophil degranulation +3 more

Viral life cycle - HIV-1 Hepatitis C Measles Influenza A Human papillomavirus infection Coronavirus disease - COVID-19 ISG15 antiviral mechanism Interferon alpha/beta signaling +5 more

Nucleocytoplasmic transport mRNA surveillance pathway Spliceosome Amyotrophic lateral sclerosis SLBP independent Processing of Histone Pre-mRNAs Formation of RNA Pol II elongation complex Formation of the Early Elongation Complex Transport of the SLBP independent Mature mRNA Transport of the SLBP Dependant Mature mRNA Transport of Mature mRNA Derived from an Intronless Transcript Transport of Mature mRNA derived from an Intron-Containing Transcript snRNP Assembly RNA Polymerase II Pre-transcription Events FGFR2 alternative splicing RNA polymerase II transcribes snRNA genes mRNA Capping mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway mRNA 3'-end processing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Termination SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs Processing of Intronless Pre-mRNAs Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) +22 more

Cell adhesion molecules Receptor-type tyrosine-protein phosphatases

Histidine metabolism Metabolic pathways Histidine catabolism

Cell adhesion molecules Receptor-type tyrosine-protein phosphatases

Defective B3GALTL causes Peters-plus syndrome (PpS) O-glycosylation of TSR domain-containing proteins

Glycerolipid metabolism Glycerophospholipid metabolism Metabolic pathways Phospholipase D signaling pathway Synthesis of PA +2 more

Cytoskeleton in muscle cells Proteoglycans in cancer Interaction between L1 and Ankyrins COPI-mediated anterograde transport +1 more

Hedgehog signaling pathway

Neuroactive ligand-receptor interaction Hormone signaling Dopaminergic synapse Dopamine receptors G alpha (i) signalling events +2 more

mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA

Nucleocytoplasmic transport mRNA surveillance pathway Spliceosome Amyotrophic lateral sclerosis SLBP independent Processing of Histone Pre-mRNAs Formation of RNA Pol II elongation complex Formation of the Early Elongation Complex Transport of the SLBP independent Mature mRNA Transport of the SLBP Dependant Mature mRNA Transport of Mature mRNA Derived from an Intronless Transcript Transport of Mature mRNA derived from an Intron-Containing Transcript snRNP Assembly RNA Polymerase II Pre-transcription Events FGFR2 alternative splicing RNA polymerase II transcribes snRNA genes mRNA Capping mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway mRNA 3'-end processing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Termination SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs Processing of Intronless Pre-mRNAs Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) +22 more