Subtype of: Thyroid neoplasms

Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
thyroid gland undifferentiated (anaplastic) carcinoma	MONDO_0006468	TP53	Causal	17638058 28631713 25295501 9861322 28351340 35478134 33428730 8408453 24423316 25862857 29615459 26878173 31621921 28781658 34972706 25940539 31319771 33912440 28481359 27785980 28423545	Open Targets	Endocrine resistance Platinum drug resistance MAPK signaling pathway +85 more
		ABL1	Unknown	28481359 29615459 28351340	Open Targets	ErbB signaling pathway Ras signaling pathway Cell cycle +17 more
		ABL2	Unknown	29615459	Open Targets	ErbB signaling pathway Ras signaling pathway Chemical carcinogenesis - reactive oxygen species +2 more
		ACSL6	Unknown	25295501	Open Targets	Fatty acid biosynthesis Fatty acid degradation Metabolic pathways +7 more
		ACVR1B	Unknown	29615459	Open Targets	Cytokine-cytokine receptor interaction TGF-beta signaling pathway Signaling pathways regulating pluripotency of stem cells +1 more
		AKT1	Unknown	28481359 29615459 28351340	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Platinum drug resistance +131 more
		AKT2	Unknown	29615459 28481359	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Platinum drug resistance +122 more
		ALK	Unknown	21596819 28351340 26878173 24613930 24475247 28481359	Open Targets	Pathways in cancer Non-small cell lung cancer PD-L1 expression and PD-1 checkpoint pathway in cancer
		APC	Unknown	7962323 28351340 29615459 26878173 31621921 15650354 28481359	Open Targets	Wnt signaling pathway Hippo signaling pathway Signaling pathways regulating pluripotency of stem cells +28 more
		AR	Unknown	29615459 26878173	Open Targets	Oocyte meiosis Pathways in cancer Chemical carcinogenesis - receptor activation +7 more
		ARAF	Unknown	29615459	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +41 more
		ARID1A	Unknown	29615459 28481359 26878173 33428730	Open Targets	ATP-dependent chromatin remodeling Thermogenesis Hepatocellular carcinoma +2 more
		ARID1B	Unknown	28481359 26878173 33428730	Open Targets	ATP-dependent chromatin remodeling Thermogenesis Hepatocellular carcinoma +2 more
		ARID2	Unknown	29615459 28481359 26878173	Open Targets	ATP-dependent chromatin remodeling Hepatocellular carcinoma RMTs methylate histone arginines +1 more
		ASXL1	Unknown	29615459 28481359 31621921	Open Targets	Polycomb repressive complex UCH proteinases
		ATM	Unknown	28351340 33428730 29615459 25862857 26878173 31621921 31319771 28481359 27785980	Open Targets	Platinum drug resistance Homologous recombination NF-kappa B signaling pathway +33 more
		ATR	Unknown	29615459 26878173 33428730	Open Targets	Fanconi anemia pathway Cell cycle p53 signaling pathway +13 more
		ATRX	Unknown	29615459 28481359 26878173	Open Targets	Cell cycle
		AXIN1	Unknown	26878173 15650354	Open Targets	Wnt signaling pathway Hippo signaling pathway Signaling pathways regulating pluripotency of stem cells +28 more
		AXIN2	Unknown	25295501	Open Targets	Wnt signaling pathway Hippo signaling pathway Signaling pathways regulating pluripotency of stem cells +15 more
		B2M	Unknown	26878173	Open Targets	Antigen processing and presentation Human cytomegalovirus infection Human T-cell leukemia virus 1 infection +14 more
		BARD1	Unknown	25295501	Open Targets	Homologous recombination HDR through Single Strand Annealing (SSA) HDR through Homologous Recombination (HRR) +11 more
		BCL11B	Unknown	25295501	Open Targets	Transcriptional misregulation in cancer
		BCL9	Unknown	25295501	Open Targets	Formation of the beta-catenin:TCF transactivating complex Deactivation of the beta-catenin transactivating complex
		BCOR	Unknown	29615459 28481359 26878173 33428730	Open Targets	Polycomb repressive complex
		BCORL1	Unknown	29615459	Open Targets	Polycomb repressive complex
		BIRC6	Unknown	33428730	Open Targets	Ubiquitin mediated proteolysis Autophagy - animal Apoptosis - multiple species
		BRAF	Unknown	28631713 24423316 18785992 25862857 29615459 18070147 17725429 23534744 31766881 23979959 18310287 27797976 19574281 28423545 17638058 15102681 17054470 17465858 12907632 23833040 28351340 33428730 18753363 15195111 15880523 21716161 34972706 17453004 25940539 37900238 19107232 23406047 25588542 23192464 28209747 17134824 18470905 24798740 25584719 15980887 15095090 22105775 31319771 17363500 26980298 15001635 27785980 19156774 19487299 12970315 14602780 24897065 15687339 26878173 23746767 20840674 14996725 37760447 28481359	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +52 more
		BRCA1	Unknown	28481359	Open Targets	Platinum drug resistance Homologous recombination Fanconi anemia pathway +19 more
		BRCA2	Unknown	29615459 26878173	Open Targets	Homologous recombination Fanconi anemia pathway Pathways in cancer +7 more
		BRD4	Unknown	29615459	Open Targets	—
		BRIP1	Unknown	29615459	Open Targets	Homologous recombination Fanconi anemia pathway HDR through Single Strand Annealing (SSA) +8 more
		BTK	Unknown	25295501 29615459	Open Targets	NF-kappa B signaling pathway Osteoclast differentiation Platelet activation +17 more
		CACNA1D	Unknown	25295501	Open Targets	MAPK signaling pathway Calcium signaling pathway cGMP-PKG signaling pathway +35 more
		CALR	Unknown	31621921	Open Targets	Protein processing in endoplasmic reticulum Phagosome Efferocytosis +14 more
		CAMTA1	Unknown	25295501	Open Targets	—
		CARD11	Unknown	29615459 28481359 26878173 33428730	Open Targets	NF-kappa B signaling pathway T cell receptor signaling pathway B cell receptor signaling pathway +4 more
		CASP8	Unknown	29615459 27797976 26878173	Open Targets	Platinum drug resistance p53 signaling pathway Apoptosis +53 more
		CBFB	Unknown	26878173	Open Targets	RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs) Transcriptional regulation by RUNX2 RUNX1 regulates estrogen receptor mediated transcription +20 more
		CBL	Unknown	25295501	Open Targets	ErbB signaling pathway Ubiquitin mediated proteolysis Endocytosis +22 more
		CBLB	Unknown	27797976 33428730	Open Targets	ErbB signaling pathway Ubiquitin mediated proteolysis Endocytosis +5 more
		CCDC6	Unknown	21173509 9516913 10951397 16015630 19055826 24613930 20840674	Open Targets	Pathways in cancer Thyroid cancer
		CCNE1	Unknown	29615459	Open Targets	Cell cycle Oocyte meiosis p53 signaling pathway +24 more
		CD209	Unknown	25295501	Open Targets	Virion - Human immunodeficiency virus Virion - Flavivirus and Alphavirus Virion - Ebolavirus, Lyssavirus and Morbillivirus +7 more
		CD79B	Unknown	29615459	Open Targets	B cell receptor signaling pathway CD22 mediated BCR regulation Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
		CDH11	Unknown	33428730	Open Targets	Adherens junctions interactions
		CDK12	Unknown	29615459 28481359 33428730	Open Targets	TP53 Regulates Transcription of DNA Repair Genes
		CDKN1A	Unknown	29615459	Open Targets	Endocrine resistance Platinum drug resistance ErbB signaling pathway +56 more
		CDKN1B	Unknown	29615459 28481359 26878173	Open Targets	Endocrine resistance ErbB signaling pathway HIF-1 signaling pathway +28 more
		CDKN2A	Unknown	28351340 33428730 9827724 29615459 8690521 24423316 26878173 18753363 8561866 31319771 28481359 27785980	Open Targets	Endocrine resistance Platinum drug resistance Cell cycle +33 more

«‹12 3…6 ›»

Thyroid gland undifferentiated (anaplastic) carcinoma

Bookmark This Disease