Subtype of: Melanoma

Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
superficial spreading melanoma	MONDO_0020638	BARD1	Unknown	33024263	Open Targets	Homologous recombination HDR through Single Strand Annealing (SSA) HDR through Homologous Recombination (HRR) +11 more
		BAZ1A	Unknown	33024263	Open Targets	ATP-dependent chromatin remodeling
		BCL10	Unknown	33024263 26359337	Open Targets	NF-kappa B signaling pathway C-type lectin receptor signaling pathway T cell receptor signaling pathway +8 more
		BCL11A	Unknown	33024263 26359337 36219477	Open Targets	—
		BCL11B	Unknown	33024263	Open Targets	Transcriptional misregulation in cancer
		BCL2	Unknown	36219477	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Platinum drug resistance +46 more
		BCL2L12	Unknown	33024263 36219477	Open Targets	—
		BCL3	Unknown	36219477	Open Targets	C-type lectin receptor signaling pathway TNF signaling pathway
		BCL6	Unknown	33024263	Open Targets	FoxO signaling pathway Transcriptional misregulation in cancer Chemical carcinogenesis - receptor activation +3 more
		BCL7A	Unknown	30178487	Open Targets	ATP-dependent chromatin remodeling
		BCL9	Unknown	33024263 26359337	Open Targets	Formation of the beta-catenin:TCF transactivating complex Deactivation of the beta-catenin transactivating complex
		BCL9L	Unknown	33024263 36219477	Open Targets	Formation of the beta-catenin:TCF transactivating complex Deactivation of the beta-catenin transactivating complex
		BCLAF1	Unknown	33024263 36219477 30178487 26359337	Open Targets	—
		BCOR	Unknown	33024263 36219477	Open Targets	Polycomb repressive complex
		BCORL1	Unknown	33024263	Open Targets	Polycomb repressive complex
		BCR	Unknown	33024263 26359337 30178487	Open Targets	Pathways in cancer Chronic myeloid leukemia Signaling by cytosolic FGFR1 fusion mutants +2 more
		BIRC3	Unknown	33024263	Open Targets	Platinum drug resistance NF-kappa B signaling pathway Ubiquitin mediated proteolysis +23 more
		BIRC6	Unknown	33024263 26359337 30178487	Open Targets	Ubiquitin mediated proteolysis Autophagy - animal Apoptosis - multiple species
		BLM	Unknown	33024263 36219477	Open Targets	Homologous recombination Fanconi anemia pathway Processive synthesis on the C-strand of the telomere +10 more
		BMP5	Unknown	33024263 26359337 30178487	Open Targets	Cytokine-cytokine receptor interaction TGF-beta signaling pathway Hippo signaling pathway
		BMPR1A	Unknown	33024263	Open Targets	Cytokine-cytokine receptor interaction Hormone signaling TGF-beta signaling pathway +4 more
		BRAF	Unknown	21352266 33024263 36219477 17535228 21326296 18945298 15917418 20544847 22351689 19158841 25857817 20520630 16773193 23938765 23715574 24733801 15935100 22197931 24471189 16417231 16179870 21615881 15140228 24457427 22584957 19147536 16845322 15191558 24352115 25257244 22549727 20720566 22529031 25767048 16117801 30178487 15195137 15331929 28870692 24238398 18227705 20460471 21176117 28356599 22020039 23579220 21880213 19571821 24458518 16899595 22744255 20605766 25766129 26359337 25695247 25576527	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +52 more
		BRCA1	Unknown	22197931 33024263 26359337 30178487 36219477	Open Targets	Platinum drug resistance Homologous recombination Fanconi anemia pathway +19 more
		BRCA2	Unknown	33024263 36219477 30178487 22197931 26359337	Open Targets	Homologous recombination Fanconi anemia pathway Pathways in cancer +7 more
		BRD3	Unknown	33024263	Open Targets	—
		BRD4	Unknown	33024263	Open Targets	—
		BRIP1	Unknown	22197931 33024263 26359337	Open Targets	Homologous recombination Fanconi anemia pathway HDR through Single Strand Annealing (SSA) +8 more
		BTG1	Unknown	33024263	Open Targets	RNA degradation FOXO-mediated transcription of cell cycle genes
		BTG2	Unknown	33024263	Open Targets	RNA degradation TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain
		BTK	Unknown	33024263	Open Targets	NF-kappa B signaling pathway Osteoclast differentiation Platelet activation +17 more
		BUB1B	Unknown	33024263 36219477 26359337	Open Targets	Cell cycle Human T-cell leukemia virus 1 infection Inactivation of APC/C via direct inhibition of the APC/C complex +9 more
		CACNA1D	Unknown	33024263 26359337 30178487	Open Targets	MAPK signaling pathway Calcium signaling pathway cGMP-PKG signaling pathway +35 more
		CALR	Unknown	33024263 26359337	Open Targets	Protein processing in endoplasmic reticulum Phagosome Efferocytosis +14 more
		CAMTA1	Unknown	33024263 26359337 30178487 36219477	Open Targets	—
		CANT1	Unknown	33024263	Open Targets	Purine metabolism Pyrimidine metabolism Metabolic pathways +2 more
		CARD11	Unknown	22197931 33024263 30178487	Open Targets	NF-kappa B signaling pathway T cell receptor signaling pathway B cell receptor signaling pathway +4 more
		CARS1	Unknown	33024263 26359337	Open Targets	Aminoacyl-tRNA biosynthesis Cytosolic tRNA aminoacylation
		CASP3	Unknown	33024263 26359337	Open Targets	Platinum drug resistance MAPK signaling pathway p53 signaling pathway +53 more
		CASP8	Unknown	36219477	Open Targets	Platinum drug resistance p53 signaling pathway Apoptosis +53 more
		CASP9	Unknown	33024263	Open Targets	Platinum drug resistance p53 signaling pathway PI3K-Akt signaling pathway +39 more
		CBFA2T3	Unknown	33024263	Open Targets	—
		CBFB	Unknown	36219477	Open Targets	RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs) Transcriptional regulation by RUNX2 RUNX1 regulates estrogen receptor mediated transcription +20 more
		CBL	Unknown	33024263	Open Targets	ErbB signaling pathway Ubiquitin mediated proteolysis Endocytosis +22 more
		CBLB	Unknown	33024263 36219477 26359337	Open Targets	ErbB signaling pathway Ubiquitin mediated proteolysis Endocytosis +5 more
		CBLC	Unknown	33024263	Open Targets	Ubiquitin mediated proteolysis Endocytosis
		CCDC6	Unknown	33024263 26359337 30178487	Open Targets	Pathways in cancer Thyroid cancer
		CCND1	Unknown	33024263 36219477	Open Targets	Endocrine resistance FoxO signaling pathway Cell cycle +58 more
		CCND2	Unknown	36219477	Open Targets	FoxO signaling pathway Cell cycle p53 signaling pathway +18 more
		CCR4	Unknown	30178487	Open Targets	Cytokine-cytokine receptor interaction Viral protein interaction with cytokine and cytokine receptor Chemokine signaling pathway +4 more
		CCR7	Unknown	33024263	Open Targets	Cytokine-cytokine receptor interaction Viral protein interaction with cytokine and cytokine receptor Chemokine signaling pathway +2 more

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Superficial spreading melanoma

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