Spastic ataxia

Oxidative phosphorylation Metabolic pathways Cardiac muscle contraction Thermogenesis Non-alcoholic fatty liver disease Alzheimer disease Parkinson disease Amyotrophic lateral sclerosis Huntington disease Prion disease Pathways of neurodegeneration - multiple diseases Chemical carcinogenesis - reactive oxygen species Diabetic cardiomyopathy TP53 Regulates Metabolic Genes Respiratory electron transport +12 more

SNARE interactions in vesicular transport Toxicity of botulinum toxin type D (BoNT/D) Toxicity of botulinum toxin type F (BoNT/F) Toxicity of botulinum toxin type G (BoNT/G) +1 more

Primary bile acid biosynthesis Metabolic pathways Peroxisome Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol Synthesis of bile acids and bile salts via 24-hydroxycholesterol Beta-oxidation of pristanoyl-CoA Peroxisomal protein import +4 more

Fat digestion and absorption Vitamin digestion and absorption Cholesterol metabolism Lipid and atherosclerosis Cell surface interactions at the vascular wall Scavenging by Class B Receptors Scavenging by Class A Receptors Scavenging by Class F Receptors Scavenging by Class H Receptors Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Platelet sensitization by LDL Regulation of TLR by endogenous ligand Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis VLDL assembly Post-translational protein phosphorylation Chylomicron assembly Chylomicron remodeling Chylomicron clearance LDL clearance LDL remodeling VLDL clearance Retinoid metabolism and transport +20 more

MAPK signaling pathway Calcium signaling pathway Synaptic vesicle cycle Retrograde endocannabinoid signaling Glutamatergic synapse Cholinergic synapse Serotonergic synapse GABAergic synapse Dopaminergic synapse Long-term depression Taste transduction Type II diabetes mellitus Spinocerebellar ataxia Morphine addiction Nicotine addiction Chemical carcinogenesis - receptor activation Presynaptic depolarization and calcium channel opening Regulation of insulin secretion +15 more

Hyaluronan uptake and degradation

Sphingolipid de novo biosynthesis

Gap junction assembly

Calcium signaling pathway cGMP-PKG signaling pathway Phosphatidylinositol signaling system Oocyte meiosis Autophagy - animal Apoptosis Cellular senescence Vascular smooth muscle contraction Apelin signaling pathway Osteoclast differentiation Gap junction Platelet activation NOD-like receptor signaling pathway C-type lectin receptor signaling pathway Circadian entrainment Long-term potentiation Retrograde endocannabinoid signaling Glutamatergic synapse Cholinergic synapse Serotonergic synapse Dopaminergic synapse Long-term depression Inflammatory mediator regulation of TRP channels GnRH signaling pathway Estrogen signaling pathway Thyroid hormone synthesis Oxytocin signaling pathway Glucagon signaling pathway Renin secretion Aldosterone synthesis and secretion Cortisol synthesis and secretion Parathyroid hormone synthesis, secretion and action GnRH secretion Cushing syndrome Growth hormone synthesis, secretion and action Salivary secretion Gastric acid secretion Pancreatic secretion Alzheimer disease Parkinson disease Huntington disease Spinocerebellar ataxia Prion disease Pathways of neurodegeneration - multiple diseases Shigellosis Human cytomegalovirus infection Kaposi sarcoma-associated herpesvirus infection Human immunodeficiency virus 1 infection Proteoglycans in cancer Lipid and atherosclerosis Effects of PIP2 hydrolysis Elevation of cytosolic Ca2+ levels Glucagon-like Peptide-1 (GLP1) regulates insulin secretion cGMP effects Ion homeostasis Antigen activates B Cell Receptor (BCR) leading to generation of second messengers +53 more

cGMP-PKG signaling pathway Vascular smooth muscle contraction Insulin secretion Renin secretion Salivary secretion Pancreatic secretion Ca2+ activated K+ channels +4 more

Motor proteins COPI-dependent Golgi-to-ER retrograde traffic Kinesins

Motor proteins COPI-dependent Golgi-to-ER retrograde traffic Kinesins

Hedgehog 'off' state Anchoring of the basal body to the plasma membrane

Glycosaminoglycan degradation Metabolic pathways Lysosome HS-GAG degradation MPS IIIB - Sanfilippo syndrome B +2 more

cGMP-PKG signaling pathway Chemokine signaling pathway Phospholipase D signaling pathway PI3K-Akt signaling pathway Adrenergic signaling in cardiomyocytes Apelin signaling pathway Platelet activation Cholinergic synapse Oxytocin signaling pathway Toxoplasmosis Kaposi sarcoma-associated herpesvirus infection GPVI-mediated activation cascade Synthesis of PIPs at the plasma membrane G beta:gamma signalling through PI3Kgamma Erythropoietin activates Phosphoinositide-3-kinase (PI3K) +12 more

Glycerophospholipid metabolism Ether lipid metabolism Arachidonic acid metabolism Linoleic acid metabolism alpha-Linolenic acid metabolism Metabolic pathways Ras signaling pathway Efferocytosis Vascular smooth muscle contraction Fc gamma R-mediated phagocytosis Inflammatory mediator regulation of TRP channels Acyl chain remodelling of PC Acyl chain remodelling of PE Role of phospholipids in phagocytosis COPI-independent Golgi-to-ER retrograde traffic +12 more

Taste transduction Phase 0 - rapid depolarisation

Phase 0 - rapid depolarisation

Selenocompound metabolism Aminoacyl-tRNA biosynthesis Metabolic pathways Selenocysteine synthesis +1 more

Sealing of the nuclear envelope (NE) by ESCRT-III

Amyotrophic lateral sclerosis Pathways of neurodegeneration - multiple diseases

Cytoskeleton in muscle cells

Protein processing in endoplasmic reticulum XBP1(S) activates chaperone genes Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation +1 more

SNARE interactions in vesicular transport Toxicity of botulinum toxin type D (BoNT/D) Toxicity of botulinum toxin type F (BoNT/F) Toxicity of botulinum toxin type G (BoNT/G) +1 more

Phagosome Apoptosis Tight junction Gap junction Motor proteins Alzheimer disease Parkinson disease Amyotrophic lateral sclerosis Huntington disease Prion disease Pathways of neurodegeneration - multiple diseases Pathogenic Escherichia coli infection Salmonella infection Platelet degranulation Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane MHC class II antigen presentation Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Regulation of PLK1 Activity at G2/M Transition HSP90 chaperone cycle for steroid hormone receptors (SHR) Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Recycling pathway of L1 Hedgehog 'off' state Cilium Assembly Anchoring of the basal body to the plasma membrane Intraflagellar transport RHO GTPases activate IQGAPs RHO GTPases Activate Formins COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic COPI-independent Golgi-to-ER retrograde traffic Mitotic Prometaphase The role of GTSE1 in G2/M progression after G2 checkpoint AURKA Activation by TPX2 Carboxyterminal post-translational modifications of tubulin HCMV Early Events Aggrephagy EML4 and NUDC in mitotic spindle formation Sealing of the nuclear envelope (NE) by ESCRT-III Kinesins +40 more

Motor proteins COPI-dependent Golgi-to-ER retrograde traffic Kinesins

Selenocompound metabolism Aminoacyl-tRNA biosynthesis Metabolic pathways Mitochondrial tRNA aminoacylation +1 more

Spinocerebellar ataxia Processing of SMDT1

Phagosome Gap junction Motor proteins Alzheimer disease Parkinson disease Amyotrophic lateral sclerosis Huntington disease Prion disease Pathways of neurodegeneration - multiple diseases Pathogenic Escherichia coli infection Salmonella infection Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane MHC class II antigen presentation Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion HSP90 chaperone cycle for steroid hormone receptors (SHR) Recruitment of NuMA to mitotic centrosomes Recycling pathway of L1 Hedgehog 'off' state Cilium Assembly Intraflagellar transport RHO GTPases activate IQGAPs RHO GTPases Activate Formins COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic COPI-independent Golgi-to-ER retrograde traffic Mitotic Prometaphase The role of GTSE1 in G2/M progression after G2 checkpoint Carboxyterminal post-translational modifications of tubulin HCMV Early Events Aggrephagy EML4 and NUDC in mitotic spindle formation Sealing of the nuclear envelope (NE) by ESCRT-III Kinesins +31 more

Sealing of the nuclear envelope (NE) by ESCRT-III

Arginine biosynthesis Alanine, aspartate and glutamate metabolism D-Amino acid metabolism Metabolic pathways Glutamatergic synapse GABAergic synapse Proximal tubule bicarbonate reclamation MicroRNAs in cancer Central carbon metabolism in cancer Glutamate Neurotransmitter Release Cycle TP53 Regulates Metabolic Genes Glutamate and glutamine metabolism +9 more

Arginine biosynthesis Alanine, aspartate and glutamate metabolism D-Amino acid metabolism Metabolic pathways Glutamatergic synapse GABAergic synapse Proximal tubule bicarbonate reclamation MicroRNAs in cancer Central carbon metabolism in cancer Glutamate Neurotransmitter Release Cycle TP53 Regulates Metabolic Genes Glutamate and glutamine metabolism +9 more