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Shy-drager syndrome
Shy-drager syndrome
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Pathways column key:
KEGG
Reactome
Disease Term
Disease ID
Gene Symbol
Classification
References
Source
Pathways
SHY-DRAGER SYNDROME
C0037019
MESH:D012791
AVP
Unknown
6850280
CTD
,
Disgenet
Phospholipase D signaling pathway
Neuroactive ligand-receptor interaction
Hormone signaling
Vascular smooth muscle contraction
Vasopressin-regulated water reabsorption
Vasopressin-like receptors
G alpha (q) signalling events
G alpha (s) signalling events
Vasopressin regulates renal water homeostasis via Aquaporins
Defective AVP does not bind AVPR1A,B and causes neurohypophyseal diabetes insipidus (NDI)
Transport of organic anions
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis
Defective AVP does not bind AVPR2 and causes neurohypophyseal diabetes insipidus (NDI)
ADORA2B mediated anti-inflammatory cytokines production
+12 more
COQ2
Unknown
—
Disgenet
Ubiquinone and other terpenoid-quinone biosynthesis
Metabolic pathways
Biosynthesis of cofactors
KLK6
Unknown
—
Disgenet
—
All
3
Causal
0
Unknown
3
Select all
Clear
ClinVar
0
Orphanet
0
Disgenet
3
CTD
1
HPO
0
GWAS catalog
0
GenCC
0
ClinGen
0
Related Diseases
Diseases that share the most curated genes with Shy-drager syndrome.
5
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Arginine vasopressin deficiency
1 shared gene
AVP
Related via 1 shared gene including AVP.
Hereditary arginine vasopressin deficiency
1 shared gene
AVP
Related via 1 shared gene including AVP.
Neurogenic diabetes insipidus
1 shared gene
AVP
Related via 1 shared gene including AVP.
Diabetes insipidus
1 shared gene
AVP
Related via 1 shared gene including AVP.
Nephrogenic diabetes insipidus
1 shared gene
AVP
Related via 1 shared gene including AVP.
1
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