Subtype of: Salivary gland neoplasms

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
salivary gland mucoepidermoid carcinoma	MONDO_0021009	AFF4	Unknown	27340278	Open Targets	Viral life cycle - HIV-1 Formation of RNA Pol II elongation complex RNA Polymerase II Pre-transcription Events +1 more
		AMER1	Unknown	34011559	Open Targets	Degradation of beta-catenin by the destruction complex Beta-catenin phosphorylation cascade Disassembly of the destruction complex and recruitment of AXIN to the membrane +8 more
		ARHGAP5	Unknown	34011559	Open Targets	Focal adhesion Leukocyte transendothelial migration Rho GTPase cycle
		CBLB	Unknown	34011559	Open Targets	ErbB signaling pathway Ubiquitin mediated proteolysis Endocytosis +5 more
		CDKN2A	Unknown	19827123 26373574 27334835	Open Targets	Endocrine resistance Platinum drug resistance Cell cycle +33 more
		CEP43	Unknown	27340278	Open Targets	Signaling by cytosolic FGFR1 fusion mutants Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes +6 more
		CHCHD7	Unknown	21394649	Open Targets	—
		CHD4	Unknown	34011559	Open Targets	ATP-dependent chromatin remodeling Human papillomavirus infection Viral carcinogenesis +5 more
		CIC	Unknown	34011559	Open Targets	Spinocerebellar ataxia
		CRTC3	Unknown	21668476 18050304 19749740	Open Targets	Human T-cell leukemia virus 1 infection Transcriptional activation of mitochondrial biogenesis Circadian Clock
		ELF3	Unknown	33832503	Open Targets	Pre-NOTCH Transcription and Translation
		EWSR1	Unknown	18338330	Open Targets	Transcriptional misregulation in cancer
		FHIT	Unknown	21394649	Open Targets	Purine metabolism Metabolic pathways Small cell lung cancer +1 more
		GNAS	Unknown	33832503	Open Targets	Endocrine resistance Rap1 signaling pathway Calcium signaling pathway +58 more
		HMGA2	Unknown	21394649	Open Targets	Transcriptional misregulation in cancer MicroRNAs in cancer Formation of Senescence-Associated Heterochromatin Foci (SAHF)
		HRAS	Unknown	10649241 23933559 27334835 27442865 28481359 32557577	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +134 more
		KRAS	Unknown	23933559	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +134 more
		LIFR	Unknown	21394649	Open Targets	Cytokine-cytokine receptor interaction Signaling pathways regulating pluripotency of stem cells JAK-STAT signaling pathway +2 more
		MPL	Unknown	34011559	Open Targets	Cytokine-cytokine receptor interaction Hormone signaling JAK-STAT signaling pathway
		MUC16	Unknown	34011559	Open Targets	Defective GALNT3 causes familial hyperphosphatemic tumoral calcinosis (HFTC) Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS) Defective GALNT12 causes colorectal cancer 1 (CRCS1) +3 more
		MYB	Unknown	19841262	Open Targets	PI3K-Akt signaling pathway RUNX1 regulates transcription of genes involved in differentiation of HSCs Estrogen-dependent gene expression
		MYH9	Unknown	34011559	Open Targets	Virion - Lassa virus and SFTS virus Vascular smooth muscle contraction Tight junction +8 more
		NFIB	Unknown	21394649 19841262	Open Targets	—
		NIN	Unknown	34011559	Open Targets	—
		PCM1	Unknown	34011559	Open Targets	Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes +4 more
		PLAG1	Unknown	21394649	Open Targets	—
		POU5F1	Unknown	18338330	Open Targets	Signaling pathways regulating pluripotency of stem cells POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation +1 more
		PTEN	Unknown	12370746 27334835 28481359	Open Targets	Inositol phosphate metabolism Metabolic pathways EGFR tyrosine kinase inhibitor resistance +37 more
		PWWP2A	Unknown	34011559	Open Targets	—
		SETD1B	Unknown	34011559	Open Targets	Lysine degradation Metabolic pathways PKMTs methylate histone lysines +1 more
		SF3B1	Unknown	34011559	Open Targets	Spliceosome B-WICH complex positively regulates rRNA expression mRNA Splicing - Major Pathway +1 more
		TCEA1	Unknown	21394649	Open Targets	Formation of RNA Pol II elongation complex RNA Polymerase II Pre-transcription Events Formation of TC-NER Pre-Incision Complex +5 more
		USP9X	Unknown	34011559	Open Targets	Downregulation of SMAD2/3:SMAD4 transcriptional activity Ub-specific processing proteases Synthesis of active ubiquitin: roles of E1 and E2 enzymes +2 more
		WIF1	Unknown	21394649	Open Targets	Wnt signaling pathway

Salivary gland mucoepidermoid carcinoma

Bookmark This Disease