Rectum malignant melanoma | Gene-Disease Associations & Pathways | GeDiPNet

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Subtype of: Melanoma

Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
rectum malignant melanoma	MONDO_0002167	ATF1	Unknown	18408594	Open Targets	Aldosterone synthesis and secretion Transcriptional misregulation in cancer CREB phosphorylation +1 more
		BCOR	Unknown	28467829	Open Targets	Polycomb repressive complex
		BRAF	Unknown	23110010 21569090 22154054 23014346 28481359	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +52 more
		BRD3	Unknown	28467829	Open Targets	—
		CTNNB1	Unknown	28481359	Open Targets	Rap1 signaling pathway Wnt signaling pathway Hippo signaling pathway +51 more
		EP300	Unknown	28481359	Open Targets	Polycomb repressive complex Viral life cycle - HIV-1 cAMP signaling pathway +66 more
		EPHA3	Unknown	28481359	Open Targets	Axon guidance EPH-Ephrin signaling EPHA-mediated growth cone collapse +1 more
		EWSR1	Unknown	18408594	Open Targets	Transcriptional misregulation in cancer
		GNAQ	Unknown	28467829	Open Targets	Rap1 signaling pathway Calcium signaling pathway cGMP-PKG signaling pathway +52 more
		GRIN2A	Unknown	21499247	Open Targets	Ras signaling pathway Rap1 signaling pathway Calcium signaling pathway +19 more
		KIT	Unknown	21569090 22154054 22261812 20372153 18421059 22068222 28481359	Open Targets	MAPK signaling pathway Ras signaling pathway Rap1 signaling pathway +15 more
		MSH2	Unknown	28481359	Open Targets	Platinum drug resistance Mismatch repair Pathways in cancer +7 more
		NCOR1	Unknown	28481359	Open Targets	Endocrine resistance TGF-beta signaling pathway Thyroid hormone signaling pathway +16 more
		NF1	Unknown	28481359 30847022	Open Targets	EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway Ras signaling pathway +2 more
		NRAS	Unknown	21569090 28481359 22261812	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +130 more
		NSD1	Unknown	28481359	Open Targets	Lysine degradation Metabolic pathways PKMTs methylate histone lysines
		PMS1	Unknown	28467829	Open Targets	—
		RAC1	Unknown	28481359	Open Targets	MAPK signaling pathway Ras signaling pathway Rap1 signaling pathway +89 more
		RAD50	Unknown	28481359	Open Targets	Homologous recombination Non-homologous end-joining Cellular senescence +14 more
		RB1	Unknown	28481359	Open Targets	Endocrine resistance Cell cycle Cellular senescence +30 more
		RMI2	Unknown	28467829	Open Targets	Fanconi anemia pathway HDR through Single Strand Annealing (SSA) HDR through Homologous Recombination (HRR) +7 more
		SF3B1	Unknown	28481359 30847022	Open Targets	Spliceosome B-WICH complex positively regulates rRNA expression mRNA Splicing - Major Pathway +1 more
		SOCS1	Unknown	28467829	Open Targets	Ubiquitin mediated proteolysis Osteoclast differentiation JAK-STAT signaling pathway +13 more
		TP53	Unknown	28481359	Open Targets	Endocrine resistance Platinum drug resistance MAPK signaling pathway +85 more