Rectum adenoma | Gene-Disease Associations & Pathways | GeDiPNet

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Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
rectum adenoma	MONDO_0000530	ALK	Unknown	23204322	Open Targets	Pathways in cancer Non-small cell lung cancer PD-L1 expression and PD-1 checkpoint pathway in cancer
		APC	Unknown	23204322 19026650 16258065 12117880 22287596 28548127	Open Targets	Wnt signaling pathway Hippo signaling pathway Signaling pathways regulating pluripotency of stem cells +28 more
		ATP2B3	Unknown	23204322	Open Targets	Calcium signaling pathway cGMP-PKG signaling pathway cAMP signaling pathway +9 more
		BIRC6	Unknown	23204322	Open Targets	Ubiquitin mediated proteolysis Autophagy - animal Apoptosis - multiple species
		BRAF	Unknown	23204322 21953887 22233696 27239120 28548127	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +52 more
		CDH10	Unknown	23204322	Open Targets	Adherens junctions interactions
		CTNNB1	Unknown	12838317	Open Targets	Rap1 signaling pathway Wnt signaling pathway Hippo signaling pathway +51 more
		FBXW7	Unknown	19420964	Open Targets	Ubiquitin mediated proteolysis Constitutive Signaling by NOTCH1 PEST Domain Mutants Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling +3 more
		KIAA1549	Unknown	23204322	Open Targets	Signaling by BRAF and RAF fusions
		KRAS	Unknown	11751493 3587348 11815980 22233696 11215737 19797612 22848674 28548127 7731696 12012008 7578594	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +134 more
		NR4A3	Unknown	23204322	Open Targets	Transcriptional misregulation in cancer Nuclear Receptor transcription pathway RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
		NRAS	Unknown	23204322 28548127	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +130 more
		NTRK2	Unknown	23204322	Open Targets	MAPK signaling pathway Ras signaling pathway Calcium signaling pathway +6 more
		PTPRK	Unknown	23204322	Open Targets	EGFR downregulation
		RNF43	Unknown	28548127	Open Targets	Wnt signaling pathway Regulation of FZD by ubiquitination RNF mutants show enhanced WNT signaling and proliferation
		STK11	Unknown	9731485	Open Targets	FoxO signaling pathway Hormone signaling Autophagy - animal +9 more
		TGFBR2	Unknown	8978340	Open Targets	MAPK signaling pathway Cytokine-cytokine receptor interaction FoxO signaling pathway +28 more
		TP53	Unknown	23204322 12010886 14688025	Open Targets	Endocrine resistance Platinum drug resistance MAPK signaling pathway +85 more
		TRRAP	Unknown	23204322	Open Targets	ATP-dependent chromatin remodeling Human T-cell leukemia virus 1 infection Formation of the beta-catenin:TCF transactivating complex +1 more