Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
PROSTATIC NEOPLASMS	MESH:D011471	KDELR1	Unknown	17013881	CTD	Vibrio cholerae infection COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic
		KDM6A	Unknown	29610475	CTD	Transcriptional misregulation in cancer HDMs demethylate histones
		KEAP1	Unknown	24763052 29610475	CTD	Ubiquitin mediated proteolysis Parkinson disease Pathways in cancer +6 more
		KLF15	Unknown	17013881	CTD	—
		KLF6	Unknown	—	CTD	—
		KLK2	Unknown	15643194 17085659	CTD	Renin-angiotensin system Endocrine and other factor-regulated calcium reabsorption Activation of Matrix Metalloproteinases +2 more
		KLK3	Unknown	12644816 15790600 16424004 16442593 16984552 17003774 17148459 18264097 18500220 18676866 27318894	CTD	Pathways in cancer Prostate cancer Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) +1 more
		KLK5	Unknown	16517595	CTD	Formation of the cornified envelope
		KMT2A	Unknown	29610475	CTD	Lysine degradation Metabolic pathways Cushing syndrome +4 more
		KMT2C	Unknown	29610475	CTD	Lysine degradation Metabolic pathways PKMTs methylate histone lysines +1 more
		KMT2D	Unknown	29610475	CTD	Lysine degradation Metabolic pathways Cushing syndrome +4 more
		KRAS	Unknown	29610475	CTD	EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +134 more
		LAMB2	Unknown	17013881	CTD	PI3K-Akt signaling pathway Focal adhesion ECM-receptor interaction +9 more
		LAMC1	Unknown	17199135	CTD	PI3K-Akt signaling pathway Focal adhesion ECM-receptor interaction +10 more
		LCE2B	Unknown	29662167	CTD	Formation of the cornified envelope
		LDAH	Unknown	20676098	CTD	—
		LDHB	Unknown	17566973	CTD	Glycolysis / Gluconeogenesis Cysteine and methionine metabolism Pyruvate metabolism +6 more
		LEP	Unknown	15042602	CTD	Cytokine-cytokine receptor interaction Neuroactive ligand-receptor interaction Hormone signaling +7 more
		LIFR	Unknown	19208208	CTD	Cytokine-cytokine receptor interaction Signaling pathways regulating pluripotency of stem cells JAK-STAT signaling pathway +2 more
		LITAF	Unknown	29845714	CTD	Lysosome
		LMTK2	Unknown	18264097	CTD	—
		LPAR1	Unknown	16809448	CTD	Rap1 signaling pathway Phospholipase D signaling pathway Neuroactive ligand-receptor interaction +8 more
		LPL	Unknown	15386377	CTD	Glycerolipid metabolism PPAR signaling pathway Cholesterol metabolism +5 more
		LRP1B	Unknown	29662167	CTD	—
		LRP2	Unknown	22919386	CTD	Hedgehog signaling pathway Thyroid hormone synthesis Cholesterol metabolism +4 more
		LZTS1	Unknown	12377406	CTD	—
		M6PR	Unknown	17199135	CTD	Lysosome Phagosome Salmonella infection +4 more
		MACIR	Unknown	30705370	CTD	—
		MAD1L1	Unknown	—	CTD	Cell cycle Oocyte meiosis Progesterone-mediated oocyte maturation +8 more
		MAP2K1	Unknown	32512071	CTD	EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +99 more
		MAP2K2	Unknown	32512071	CTD	EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +87 more
		MAP2K3	Unknown	32512071	CTD	MAPK signaling pathway Rap1 signaling pathway Cellular senescence +21 more
		MAP2K5	Unknown	32512071	CTD	MAPK signaling pathway Gap junction Neurotrophin signaling pathway +2 more
		MAP2K6	Unknown	32512071	CTD	MAPK signaling pathway Rap1 signaling pathway Cellular senescence +27 more
		MAP3K1	Unknown	29662167	CTD	MAPK signaling pathway Ubiquitin mediated proteolysis Tight junction +11 more
		MAP3K7	Unknown	17199135	CTD	MAPK signaling pathway NF-kappa B signaling pathway Autophagy - animal +42 more
		MAPK3	Unknown	24763052	CTD	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Platinum drug resistance +158 more
		MAPK9	Unknown	32512071	CTD	Endocrine resistance MAPK signaling pathway ErbB signaling pathway +74 more
		MATN4	Unknown	29610475	CTD	ECM proteoglycans
		MBD1	Unknown	29610475	CTD	SUMOylation of transcription cofactors
		MBD2	Unknown	17013881	CTD	ATP-dependent chromatin remodeling NoRC negatively regulates rRNA expression RNA Polymerase I Promoter Opening
		MBTPS1	Unknown	17013881	CTD	Protein processing in endoplasmic reticulum Regulation of cholesterol biosynthesis by SREBP (SREBF) ATF6 (ATF6-alpha) activates chaperones +3 more
		MC2R	Unknown	17013881	CTD	cAMP signaling pathway Neuroactive ligand-receptor interaction Hormone signaling +7 more
		MDM2	Unknown	20875869	CTD	Endocrine resistance Platinum drug resistance FoxO signaling pathway +35 more
		MED12	Unknown	22610119 29610475	CTD	Thyroid hormone signaling pathway PPARA activates gene expression Generic Transcription Pathway +1 more
		MET	Unknown	29610475	CTD	EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway Ras signaling pathway +37 more
		MGA	Unknown	29610475	CTD	Polycomb repressive complex Transcriptional Regulation by E2F6
		MIF	Unknown	17728788	CTD	Tyrosine metabolism Phenylalanine metabolism Metabolic pathways +3 more
		MLH1	Unknown	15583422	CTD	Platinum drug resistance Mismatch repair Fanconi anemia pathway +8 more
		MME	Unknown	17173048	CTD	Renin-angiotensin system Hematopoietic cell lineage Protein digestion and absorption +3 more

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Prostatic neoplasms

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