Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
LEUKEMIA, PROMYELOCYTIC, ACUTE	MESH:D015473	ABCA1	Unknown	32929351	CTD	ABC transporters Efferocytosis Fat digestion and absorption +6 more
		AKT1	Unknown	12556562	CTD	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Platinum drug resistance +131 more
		AQP9	Unknown	23563754	CTD	Neutrophil extracellular trap formation Bile secretion Transport of glycerol from adipocytes to the liver by Aquaporins +1 more
		ASXL1	Unknown	26285909	CTD	Polycomb repressive complex UCH proteinases
		BIRC5	Unknown	27770503	CTD	Platinum drug resistance Apoptosis Apoptosis - multiple species +15 more
		CD44	Unknown	16208414 17349212	CTD	ECM-receptor interaction Hematopoietic cell lineage Shigellosis +9 more
		CEBPA	Unknown	16788101 26285909	CTD	Non-alcoholic fatty liver disease Pathways in cancer Transcriptional misregulation in cancer +3 more
		CEBPE	Unknown	16788101	CTD	Transcriptional misregulation in cancer Acute myeloid leukemia
		DAPK2	Unknown	28978663	CTD	Autophagy - animal Pathways in cancer Bladder cancer
		DEFA3	Unknown	16019513	CTD	NOD-like receptor signaling pathway Staphylococcus aureus infection Transcriptional misregulation in cancer +2 more
		DHCR7	Unknown	32929351	CTD	Steroid biosynthesis Metabolic pathways Activation of gene expression by SREBF (SREBP) +2 more
		DNMT3A	Unknown	26285909	CTD	Cysteine and methionine metabolism Metabolic pathways Efferocytosis +3 more
		F3	Unknown	16206674	CTD	Complement and coagulation cascades AGE-RAGE signaling pathway in diabetic complications Extrinsic Pathway of Fibrin Clot Formation +1 more
		FLT3	Unknown	17454189 24160850 26285909	CTD	MAPK signaling pathway Ras signaling pathway PI3K-Akt signaling pathway +8 more
		FNDC3B	Unknown	28314734	CTD	—
		GLI1	Unknown	23867347	CTD	cAMP signaling pathway Hedgehog signaling pathway Pathways in cancer +5 more
		GLI2	Unknown	23867347	CTD	Hedgehog signaling pathway Hippo signaling pathway Pathways in cancer +4 more
		GPHN	Unknown	32929351	CTD	Folate biosynthesis Metabolic pathways Biosynthesis of cofactors +2 more
		IDH1	Unknown	26285909	CTD	Citrate cycle (TCA cycle) Glutathione metabolism Metabolic pathways +9 more
		IDH2	Unknown	26285909	CTD	Citrate cycle (TCA cycle) Glutathione metabolism Metabolic pathways +7 more
		IFNG	Unknown	22617429	CTD	Proteasome Cytokine-cytokine receptor interaction HIF-1 signaling pathway +33 more
		IL17A	Unknown	22617429	CTD	Cytokine-cytokine receptor interaction IL-17 signaling pathway Th17 cell differentiation +5 more
		IRF2BP2	Unknown	25583766	CTD	—
		ITGAL	Unknown	16764927	CTD	Rap1 signaling pathway Cell adhesion molecules Neutrophil extracellular trap formation +14 more
		ITGAM	Unknown	16764927	CTD	Rap1 signaling pathway Phagosome Cell adhesion molecules +18 more
		ITGAX	Unknown	16764927	CTD	Complement and coagulation cascades Regulation of actin cytoskeleton Tuberculosis +5 more
		ITGB2	Unknown	16764927	CTD	Rap1 signaling pathway Phagosome Hippo signaling pathway +22 more
		KIT	Unknown	26285909	CTD	MAPK signaling pathway Ras signaling pathway Rap1 signaling pathway +15 more
		LAT2	Unknown	32587277	CTD	Natural killer cell mediated cytotoxicity Role of LAT2/NTAL/LAB on calcium mobilization
		LEP	Unknown	32929351	CTD	Cytokine-cytokine receptor interaction Neuroactive ligand-receptor interaction Hormone signaling +7 more
		LTC4S	Unknown	32929351	CTD	Arachidonic acid metabolism Metabolic pathways Synthesis of 5-eicosatetraenoic acids +4 more
		ME1	Unknown	32929351	CTD	Pyruvate metabolism Metabolic pathways Carbon metabolism +3 more
		MTARC2	Unknown	32929351	CTD	Phase I - Functionalization of compounds
		NPM1	Unknown	14508522 26285909	CTD	Nuclear import of Rev protein SUMOylation of transcription cofactors Deposition of new CENPA-containing nucleosomes at the centromere +2 more
		NRAS	Unknown	26285909	CTD	EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +130 more
		PML	Unknown	10742073 14706140 16788101 16835227 16891316 16935935 17294898 17649720 19029980 19035177 19884644 19887701 21345080 21613260 22213200 23208507 23734343 26285909 26728337 32882258 32929351 8616088	CTD	Ubiquitin mediated proteolysis Endocytosis Influenza A +12 more
		PPARG	Unknown	32929351	CTD	PPAR signaling pathway Efferocytosis AMPK signaling pathway +13 more
		PRKAR1A	Unknown	17712046	CTD	Insulin signaling pathway PKA activation PKA activation in glucagon signalling +7 more
		PTPN11	Unknown	32417439	CTD	Ras signaling pathway Phospholipase D signaling pathway Efferocytosis +56 more
		RAP1GAP	Unknown	22614916	CTD	Rap1 signaling pathway Rap1 signalling RET signaling
		RARA	Unknown	10742073 14508522 14706140 16239915 16788101 16835227 16891316 16935935 17294898 17649720 17712046 19029980 19035177 19884644 19887701 21613260 22213200 23208507 25583766 26285909 26728337 28314734 32882258 32929351 8616088	CTD	Th17 cell differentiation Estrogen signaling pathway Pathways in cancer +6 more
		RETN	Unknown	32929351	CTD	Neutrophil degranulation
		ROCK1	Unknown	32417439	CTD	cGMP-PKG signaling pathway cAMP signaling pathway Chemokine signaling pathway +25 more
		SLIT2	Unknown	33120864	CTD	Axon guidance Signaling by ROBO receptors Role of ABL in ROBO-SLIT signaling +2 more
		SMO	Unknown	23867347	CTD	Hedgehog signaling pathway Axon guidance Pathways in cancer +6 more
		TET2	Unknown	26285909	CTD	—
		THBD	Unknown	16206674	CTD	Complement and coagulation cascades AGE-RAGE signaling pathway in diabetic complications Fluid shear stress and atherosclerosis +2 more
		TRIB3	Unknown	32929351	CTD	Insulin resistance PIP3 activates AKT signaling Activation of AKT2 +4 more
		WT1	Unknown	26285909	CTD	Transcriptional misregulation in cancer
		ZBTB16	Unknown	23208507	CTD	Pathways in cancer Transcriptional misregulation in cancer Acute myeloid leukemia +2 more

Promyelocytic leukemia

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