Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
plasma cell myeloma	MONDO_0009693	OLIG2	Unknown	24434212	Open Targets	—
		OMD	Unknown	24434212	Open Targets	Keratan sulfate biosynthesis Keratan sulfate degradation Defective CHST6 causes MCDC1 +2 more
		PABPC1	Unknown	30545397 24434212	Open Targets	mRNA surveillance pathway RNA degradation L13a-mediated translational silencing of Ceruloplasmin expression +5 more
		PAFAH1B2	Unknown	24434212	Open Targets	Ether lipid metabolism Metabolic pathways Neutrophil degranulation +1 more
		PALB2	Unknown	30545397 24434212	Open Targets	Homologous recombination Fanconi anemia pathway HDR through Homologous Recombination (HRR) +3 more
		PATZ1	Unknown	35045690 23396385 24434212	Open Targets	—
		PAX3	Unknown	24434212	Open Targets	Transcriptional misregulation in cancer HATs acetylate histones
		PAX5	Unknown	30545397 35045690 29563506 24434212	Open Targets	Transcriptional misregulation in cancer RUNX1 regulates transcription of genes involved in BCR signaling
		PAX7	Unknown	35045690 22573403 24434212	Open Targets	Transcriptional misregulation in cancer
		PAX8	Unknown	30545397 24434212	Open Targets	Thyroid hormone synthesis Pathways in cancer Transcriptional misregulation in cancer +1 more
		PBRM1	Unknown	30545397 23396385 24434212	Open Targets	ATP-dependent chromatin remodeling Hepatocellular carcinoma RMTs methylate histone arginines +1 more
		PBX1	Unknown	35045690 30545397 24434212	Open Targets	Efferocytosis Cortisol synthesis and secretion Cushing syndrome +3 more
		PCBP1	Unknown	30545397	Open Targets	Spliceosome Ferroptosis Cytosolic DNA-sensing pathway +2 more
		PCM1	Unknown	25794135 30545397 24434212	Open Targets	Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes +4 more
		PDCD1LG2	Unknown	24434212	Open Targets	Cell adhesion molecules PD-1 signaling
		PDE4DIP	Unknown	35045690 29563506 22573403 24434212	Open Targets	—
		PDGFB	Unknown	24434212	Open Targets	EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway Ras signaling pathway +25 more
		PDGFRA	Unknown	35045690 24335104 24434212	Open Targets	EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway Ras signaling pathway +30 more
		PDGFRB	Unknown	30545397 24434212	Open Targets	EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway Ras signaling pathway +22 more
		PER1	Unknown	30545397 24434212	Open Targets	Circadian rhythm Circadian entrainment
		PHF6	Unknown	35045690 29386642 24434212	Open Targets	ATP-dependent chromatin remodeling
		PHOX2B	Unknown	29563506 24434212	Open Targets	—
		PICALM	Unknown	30545397 24434212	Open Targets	Golgi Associated Vesicle Biogenesis Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
		PIERCE2	Unknown	24434212	Open Targets	—
		PIK3CA	Unknown	28492226 29563506 22939401 24434212	Open Targets	Inositol phosphate metabolism Metabolic pathways EGFR tyrosine kinase inhibitor resistance +149 more
		PIK3CB	Unknown	30545397 24434212	Open Targets	Inositol phosphate metabolism Metabolic pathways EGFR tyrosine kinase inhibitor resistance +126 more
		PIK3R1	Unknown	24434212	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Platinum drug resistance +150 more
		PIK3R2	Unknown	30545397 24434212	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Platinum drug resistance +129 more
		PIK3R3	Unknown	24434212	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Platinum drug resistance +116 more
		PIM1	Unknown	29563506 28481359 24434212	Open Targets	JAK-STAT signaling pathway AGE-RAGE signaling pathway in diabetic complications Pathways in cancer +3 more
		PLAG1	Unknown	30545397 24434212	Open Targets	—
		PLCG1	Unknown	35045690 30545397 24434212	Open Targets	Inositol phosphate metabolism Metabolic pathways EGFR tyrosine kinase inhibitor resistance +70 more
		PLEC	Unknown	35045690 24434212	Open Targets	Cytoskeleton in muscle cells Assembly of collagen fibrils and other multimeric structures Caspase-mediated cleavage of cytoskeletal proteins +1 more
		PML	Unknown	35045690 24434212	Open Targets	Ubiquitin mediated proteolysis Endocytosis Influenza A +12 more
		PMS1	Unknown	30545397 24434212	Open Targets	—
		PMS2	Unknown	30545397 29563506 24434212	Open Targets	Mismatch repair Fanconi anemia pathway Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) +3 more
		POLD1	Unknown	30545397 24434212	Open Targets	DNA replication Base excision repair Nucleotide excision repair +19 more
		POLE	Unknown	35045690 30545397 23396385 22573403 24434212	Open Targets	DNA replication Base excision repair Nucleotide excision repair +10 more
		POLG	Unknown	35045690 30545397 24434212	Open Targets	Base excision repair
		POLQ	Unknown	30545397 35045690 29563506 22573403 24434212	Open Targets	HDR through MMEJ (alt-NHEJ)
		POT1	Unknown	35045690 30545397 24434212	Open Targets	Recognition and association of DNA glycosylase with site containing an affected purine Cleavage of the damaged purine Packaging Of Telomere Ends +2 more
		POU2AF1	Unknown	30545397 24434212	Open Targets	—
		POU5F1	Unknown	30545397 24434212	Open Targets	Signaling pathways regulating pluripotency of stem cells POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation +1 more
		PPARG	Unknown	35045690 24434212	Open Targets	PPAR signaling pathway Efferocytosis AMPK signaling pathway +13 more
		PPFIBP1	Unknown	30545397 35045690 24434212	Open Targets	Receptor-type tyrosine-protein phosphatases
		PPM1D	Unknown	24434212	Open Targets	p53 signaling pathway Transcriptional regulation by RUNX2
		PPP2R1A	Unknown	24434212	Open Targets	mRNA surveillance pathway Sphingolipid signaling pathway Cell cycle +52 more
		PPP6C	Unknown	30545397 24434212	Open Targets	COPII-mediated vesicle transport
		PRCC	Unknown	35045690 30545397 24434212	Open Targets	Transcriptional misregulation in cancer Renal cell carcinoma mRNA Splicing - Major Pathway
		PRDM1	Unknown	25302557 24434212 30545397 29563506 22573403 37452600 26918361	Open Targets	Regulation of TP53 Expression

«‹1…8 91011 12…14 ›»

Plasma cell myeloma

Bookmark This Disease