Subtype of: Pancreatic cancer

Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
pancreatic acinar cell carcinoma	MONDO_0006346	CCR7	Unknown	29109526	Open Targets	Cytokine-cytokine receptor interaction Viral protein interaction with cytokine and cytokine receptor Chemokine signaling pathway +2 more
		CD79A	Unknown	24293293	Open Targets	B cell receptor signaling pathway Primary immunodeficiency CD22 mediated BCR regulation +1 more
		CDC73	Unknown	29109526	Open Targets	Formation of RNA Pol II elongation complex Formation of the beta-catenin:TCF transactivating complex Hedgehog 'on' state +3 more
		CDH1	Unknown	28481359	Open Targets	Rap1 signaling pathway Apelin signaling pathway Hippo signaling pathway +15 more
		CDH10	Unknown	29109526	Open Targets	Adherens junctions interactions
		CDK12	Unknown	24293293	Open Targets	TP53 Regulates Transcription of DNA Repair Genes
		CDK6	Unknown	29109526 24293293	Open Targets	Cell cycle p53 signaling pathway PI3K-Akt signaling pathway +27 more
		CDKN2A	Unknown	23565280	Open Targets	Endocrine resistance Platinum drug resistance Cell cycle +33 more
		CHD4	Unknown	29109526 24293293	Open Targets	ATP-dependent chromatin remodeling Human papillomavirus infection Viral carcinogenesis +5 more
		CIC	Unknown	28481359	Open Targets	Spinocerebellar ataxia
		CLIP1	Unknown	24293293	Open Targets	mTOR signaling pathway Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids +5 more
		CLTCL1	Unknown	29109526	Open Targets	Lysosome Endocytosis Synaptic vesicle cycle +8 more
		CNOT3	Unknown	29109526	Open Targets	RNA degradation Deadenylation of mRNA TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain
		CNTNAP2	Unknown	29109526 24293293	Open Targets	Cell adhesion molecules
		COL1A1	Unknown	29109526	Open Targets	PI3K-Akt signaling pathway Focal adhesion ECM-receptor interaction +26 more
		COL2A1	Unknown	29109526 24293293	Open Targets	PI3K-Akt signaling pathway Focal adhesion ECM-receptor interaction +14 more
		COL3A1	Unknown	29109526	Open Targets	Platelet activation Cytoskeleton in muscle cells Relaxin signaling pathway +16 more
		CPEB3	Unknown	24293293	Open Targets	Oocyte meiosis Progesterone-mediated oocyte maturation
		CREBBP	Unknown	24293293	Open Targets	Polycomb repressive complex Viral life cycle - HIV-1 cAMP signaling pathway +52 more
		CRTC1	Unknown	24293293 25743105	Open Targets	Human T-cell leukemia virus 1 infection Transcriptional activation of mitochondrial biogenesis Circadian Clock
		CSMD3	Unknown	29109526 24293293	Open Targets	—
		CTCF	Unknown	29109526	Open Targets	—
		CTNNA1	Unknown	29109526 24293293	Open Targets	Hippo signaling pathway Adherens junction Leukocyte transendothelial migration +9 more
		CTNNB1	Unknown	25266736 29109526 31338587 37469257 11891193 28481359 24590585	Open Targets	Rap1 signaling pathway Wnt signaling pathway Hippo signaling pathway +51 more
		CTNND1	Unknown	29109526 24293293	Open Targets	Rap1 signaling pathway Adherens junction Leukocyte transendothelial migration +3 more
		CTNND2	Unknown	29109526 25743105	Open Targets	Wnt signaling pathway
		CUX1	Unknown	29109526 24293293	Open Targets	Signaling by cytosolic FGFR1 fusion mutants Signaling by FGFR1 in disease Intra-Golgi traffic
		DCAF12L2	Unknown	29109526 24293293	Open Targets	—
		DCC	Unknown	29109526	Open Targets	Axon guidance Pathways in cancer Colorectal cancer +3 more
		DCTN1	Unknown	24293293	Open Targets	Motor proteins Vasopressin-regulated water reabsorption Amyotrophic lateral sclerosis +15 more
		DDB2	Unknown	29109526	Open Targets	Nucleotide excision repair p53 signaling pathway Ubiquitin mediated proteolysis +23 more
		DDX6	Unknown	24293293	Open Targets	RNA degradation mRNA decay by 5' to 3' exoribonuclease
		DICER1	Unknown	29109526	Open Targets	MicroRNAs in cancer MicroRNA (miRNA) biogenesis Small interfering RNA (siRNA) biogenesis
		DNM2	Unknown	29109526	Open Targets	Phospholipase D signaling pathway Endocytosis Fc gamma R-mediated phagocytosis +13 more
		DNMT3A	Unknown	29109526	Open Targets	Cysteine and methionine metabolism Metabolic pathways Efferocytosis +3 more
		DROSHA	Unknown	29109526	Open Targets	Ribosome biogenesis in eukaryotes Proteoglycans in cancer MicroRNA (miRNA) biogenesis
		EED	Unknown	28481359	Open Targets	Polycomb repressive complex PRC2 methylates histones and DNA Oxidative Stress Induced Senescence +4 more
		EGFR	Unknown	29109526 25266736 28481359	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Virion - Hepatitis viruses +79 more
		ELF4	Unknown	29109526	Open Targets	—
		ELK4	Unknown	29109526	Open Targets	MAPK signaling pathway Human T-cell leukemia virus 1 infection Transcriptional misregulation in cancer
		ELN	Unknown	29109526	Open Targets	Cytoskeleton in muscle cells Protein digestion and absorption Degradation of the extracellular matrix +2 more
		EP300	Unknown	29109526 24293293	Open Targets	Polycomb repressive complex Viral life cycle - HIV-1 cAMP signaling pathway +66 more
		ERBB3	Unknown	29109526 24293293	Open Targets	EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway ErbB signaling pathway +19 more
		ERBB4	Unknown	29109526	Open Targets	MAPK signaling pathway ErbB signaling pathway Calcium signaling pathway +22 more
		ERC1	Unknown	29109526	Open Targets	NF-kappa B signaling pathway
		ERCC2	Unknown	24293293	Open Targets	Basal transcription factors Nucleotide excision repair Formation of RNA Pol II elongation complex +19 more
		EXT1	Unknown	29109526	Open Targets	Glycosaminoglycan biosynthesis - heparan sulfate / heparin Metabolic pathways HS-GAG biosynthesis +2 more
		EZR	Unknown	29109526 24293293	Open Targets	Tight junction Leukocyte transendothelial migration Regulation of actin cytoskeleton +6 more
		FAM131B	Unknown	29109526	Open Targets	Signaling by BRAF and RAF fusions
		FAM135B	Unknown	29109526	Open Targets	—

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Pancreatic acinar cell carcinoma

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