Subtype of: Ovarian cancer

Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
ovarian endometrioid adenocarcinoma	MONDO_0006335	ABL1	Unknown	21720365 23780408 29420467 31477716 32901952 33947352	Open Targets	ErbB signaling pathway Ras signaling pathway Cell cycle +17 more
		AFF1	Unknown	31477716 33947352	Open Targets	Transcriptional misregulation in cancer
		AKAP9	Unknown	21720365 22102435 33947352	Open Targets	Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes +7 more
		AKT2	Unknown	25846551 31477716	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Platinum drug resistance +122 more
		ALK	Unknown	21720365 28481359 33947352	Open Targets	Pathways in cancer Non-small cell lung cancer PD-L1 expression and PD-1 checkpoint pathway in cancer
		ARID1A	Unknown	20942669 21720365 22102435 23791828 23856246 25846551 26257827 26920370 28125452 28481359 29162652 29793804 30851247 31477716 31836588 32901952 33947352 35478134 36384753	Open Targets	ATP-dependent chromatin remodeling Thermogenesis Hepatocellular carcinoma +2 more
		ARID2	Unknown	21720365 26257827 26920370 28481359 29793804 33947352	Open Targets	ATP-dependent chromatin remodeling Hepatocellular carcinoma RMTs methylate histone arginines +1 more
		ATR	Unknown	21720365 25846551 28481359 29793804 32019284 33947352 36446793	Open Targets	Fanconi anemia pathway Cell cycle p53 signaling pathway +13 more
		ATRX	Unknown	21720365 23780408 26920370 27741368 28481359 29793804 33947352	Open Targets	Cell cycle
		AXIN2	Unknown	11719457 21720365 31477716	Open Targets	Wnt signaling pathway Hippo signaling pathway Signaling pathways regulating pluripotency of stem cells +15 more
		BAX	Unknown	15350299	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Platinum drug resistance +52 more
		BCL11B	Unknown	23856246 33947352	Open Targets	Transcriptional misregulation in cancer
		BCL9	Unknown	21720365 33947352	Open Targets	Formation of the beta-catenin:TCF transactivating complex Deactivation of the beta-catenin transactivating complex
		BCR	Unknown	21720365 33947352	Open Targets	Pathways in cancer Chronic myeloid leukemia Signaling by cytosolic FGFR1 fusion mutants +2 more
		CASP8	Unknown	21720365 22102435 28481359	Open Targets	Platinum drug resistance p53 signaling pathway Apoptosis +53 more
		CCND1	Unknown	28481359 33947352	Open Targets	Endocrine resistance FoxO signaling pathway Cell cycle +58 more
		CD79B	Unknown	28481359 33947352	Open Targets	B cell receptor signaling pathway CD22 mediated BCR regulation Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
		CDH1	Unknown	21720365 23791828 26920370 28481359 28498287 31477716 33947352	Open Targets	Rap1 signaling pathway Apelin signaling pathway Hippo signaling pathway +15 more
		COL1A1	Unknown	21720365 33947352	Open Targets	PI3K-Akt signaling pathway Focal adhesion ECM-receptor interaction +26 more
		COL2A1	Unknown	21720365 29162652	Open Targets	PI3K-Akt signaling pathway Focal adhesion ECM-receptor interaction +14 more
		CREBBP	Unknown	15937088 21720365 22102435 27741368 28481359 30851247 33947352	Open Targets	Polycomb repressive complex Viral life cycle - HIV-1 cAMP signaling pathway +52 more
		DDIT3	Unknown	21720365 33947352	Open Targets	MAPK signaling pathway Protein processing in endoplasmic reticulum Apoptosis +9 more
		DDX10	Unknown	29162652 31477716	Open Targets	—
		DROSHA	Unknown	21720365 25846551	Open Targets	Ribosome biogenesis in eukaryotes Proteoglycans in cancer MicroRNA (miRNA) biogenesis
		EPHA7	Unknown	21720365 28481359 33947352	Open Targets	Axon guidance EPH-Ephrin signaling EPHA-mediated growth cone collapse +1 more
		ERBB2	Unknown	15457249 16607561 21347793 21720365 26287187 28125452 28481359 29420467 29793804 32901952 33947352	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Platinum drug resistance +48 more
		ERCC2	Unknown	21720365 28481359 31477716 33947352	Open Targets	Basal transcription factors Nucleotide excision repair Formation of RNA Pol II elongation complex +19 more
		ERCC3	Unknown	21720365 28481359 33947352	Open Targets	Basal transcription factors Nucleotide excision repair Formation of RNA Pol II elongation complex +19 more
		FANCA	Unknown	21720365 27741368 28481359 31477716 32019284 33947352	Open Targets	Fanconi anemia pathway Fanconi Anemia Pathway
		FANCD2	Unknown	21720365 29793804 32019284 33947352 36446793	Open Targets	Fanconi anemia pathway Fanconi Anemia Pathway TP53 Regulates Transcription of DNA Repair Genes
		FANCF	Unknown	25846551	Open Targets	Fanconi anemia pathway Fanconi Anemia Pathway
		FAS	Unknown	29162652	Open Targets	Platinum drug resistance MAPK signaling pathway Cytokine-cytokine receptor interaction +36 more
		FGFR2	Unknown	20106510 21720365 25846456 25986173 27575406 28125452 28481359 31477716 33947352 36531003	Open Targets	EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway Ras signaling pathway +26 more
		FLT3	Unknown	21720365 23791828 26920370 28481359 29793804	Open Targets	MAPK signaling pathway Ras signaling pathway PI3K-Akt signaling pathway +8 more
		FLT4	Unknown	21720365 22102435 27741368 28481359 31477716 33947352	Open Targets	MAPK signaling pathway Ras signaling pathway Rap1 signaling pathway +6 more
		FOXL2	Unknown	28481359 33947352	Open Targets	SUMOylation of transcription factors
		FOXO1	Unknown	29333526 33947352	Open Targets	FoxO signaling pathway AMPK signaling pathway Longevity regulating pathway +23 more
		FOXP1	Unknown	21720365 31477716 33947352	Open Targets	MicroRNAs in cancer Transcriptional regulation of pluripotent stem cells
		GAS7	Unknown	29162652	Open Targets	—
		GLI1	Unknown	21720365 28481359	Open Targets	cAMP signaling pathway Hedgehog signaling pathway Pathways in cancer +5 more
		GNAS	Unknown	21720365 23791828 26257827 26920370 27588476 27741368 28481359 29793804 31477716 33947352	Open Targets	Endocrine resistance Rap1 signaling pathway Calcium signaling pathway +58 more
		HOOK3	Unknown	33947352	Open Targets	Motor proteins
		IL6ST	Unknown	21720365 33947352	Open Targets	Cytokine-cytokine receptor interaction Viral protein interaction with cytokine and cytokine receptor Signaling pathways regulating pluripotency of stem cells +12 more
		JAK3	Unknown	21720365 28481359 29420467 31477716 33947352	Open Targets	Chemokine signaling pathway PI3K-Akt signaling pathway Necroptosis +21 more
		KAT6B	Unknown	21720365 33947352	Open Targets	HATs acetylate histones
		KDR	Unknown	21720365 26920370 28481359 29793804 32901952 33947352 36531003	Open Targets	EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway Ras signaling pathway +13 more
		KMT2C	Unknown	21720365 27741368 28481359 29420467 29793804 31477716 33947352 36531003	Open Targets	Lysine degradation Metabolic pathways PKMTs methylate histone lysines +1 more
		KMT2D	Unknown	21720365 27741368 28481359 28984674 29793804 33947352	Open Targets	Lysine degradation Metabolic pathways Cushing syndrome +4 more
		KRAS	Unknown	10071245 10686936 10739698 11727259 12648581 12694651 12893203 15581971 16256179 1656759 16619251 16806438 16867867 17418409 17592266 19018267 19048115 19430562 19962665 20802181 21237491 21435433 21720365 21726664 21926912 2205377 22102435 22163003 22271473 22328975 22487539 22705003 23000388 23096461 23267135 23370429 23408974 23711666 23716351 23791828 23800114 23851676 24022196 24487474 24552895 24557434 24927217 25118479 25473748 25523272 25846456 25846551 25986173 26257827 26870997 27575406 27588476 28125452 28481359 28498287 28734796 28984674 29162652 29793804 31477716 31538426 31836588 32693840 32901952 33947352 36384753 36531003 36967525 37185420 37449085 7669582 7852189 7981904 8018414 8258728 8261457 8384077 8651354 8980248 9166952 9264581	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +134 more
		LCK	Unknown	21720365 33947352	Open Targets	NF-kappa B signaling pathway Osteoclast differentiation Natural killer cell mediated cytotoxicity +27 more

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Ovarian endometrioid adenocarcinoma

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