Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
neoplasm of mature B-cells	MONDO_0004949	ABL1	Unknown	23297126	Open Targets	ErbB signaling pathway Ras signaling pathway Cell cycle +17 more
		ABL2	Unknown	27325104	Open Targets	ErbB signaling pathway Ras signaling pathway Chemical carcinogenesis - reactive oxygen species +2 more
		ALK	Unknown	8558920 8781434 7662979	Open Targets	Pathways in cancer Non-small cell lung cancer PD-L1 expression and PD-1 checkpoint pathway in cancer
		AMER1	Unknown	28481359	Open Targets	Degradation of beta-catenin by the destruction complex Beta-catenin phosphorylation cascade Disassembly of the destruction complex and recruitment of AXIN to the membrane +8 more
		APC	Unknown	30802265	Open Targets	Wnt signaling pathway Hippo signaling pathway Signaling pathways regulating pluripotency of stem cells +28 more
		ARHGEF12	Unknown	23297126	Open Targets	Vascular smooth muscle contraction Axon guidance Platelet activation +12 more
		ARID1A	Unknown	37333831 27325104 22585168 30802265 24388756 28481359	Open Targets	ATP-dependent chromatin remodeling Thermogenesis Hepatocellular carcinoma +2 more
		ARID1B	Unknown	30802265 24388756	Open Targets	ATP-dependent chromatin remodeling Thermogenesis Hepatocellular carcinoma +2 more
		ARID2	Unknown	23297126	Open Targets	ATP-dependent chromatin remodeling Hepatocellular carcinoma RMTs methylate histone arginines +1 more
		ARNT	Unknown	23297126	Open Targets	HIF-1 signaling pathway Efferocytosis Cushing syndrome +10 more
		ASXL2	Unknown	28481359	Open Targets	Polycomb repressive complex UCH proteinases
		ATM	Unknown	30802265 12149228 12697903	Open Targets	Platinum drug resistance Homologous recombination NF-kappa B signaling pathway +33 more
		ATR	Unknown	24388756 27325104	Open Targets	Fanconi anemia pathway Cell cycle p53 signaling pathway +13 more
		ATRX	Unknown	23297126	Open Targets	Cell cycle
		AXIN1	Unknown	27325104	Open Targets	Wnt signaling pathway Hippo signaling pathway Signaling pathways regulating pluripotency of stem cells +28 more
		B2M	Unknown	30802265 37333831 28481359	Open Targets	Antigen processing and presentation Human cytomegalovirus infection Human T-cell leukemia virus 1 infection +14 more
		BAP1	Unknown	24388756	Open Targets	Polycomb repressive complex UCH proteinases Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
		BCL10	Unknown	30802265 28481359	Open Targets	NF-kappa B signaling pathway C-type lectin receptor signaling pathway T cell receptor signaling pathway +8 more
		BCL2	Unknown	37333831 30802265 24388756 21796119 23297126 28481359	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Platinum drug resistance +46 more
		BCL6	Unknown	30802265 37333831 28481359	Open Targets	FoxO signaling pathway Transcriptional misregulation in cancer Chemical carcinogenesis - receptor activation +3 more
		BCL7A	Unknown	30802265 27325104	Open Targets	ATP-dependent chromatin remodeling
		BCL9	Unknown	27325104	Open Targets	Formation of the beta-catenin:TCF transactivating complex Deactivation of the beta-catenin transactivating complex
		BCL9L	Unknown	21796119	Open Targets	Formation of the beta-catenin:TCF transactivating complex Deactivation of the beta-catenin transactivating complex
		BCLAF1	Unknown	27325104	Open Targets	—
		BCOR	Unknown	30802265 28481359	Open Targets	Polycomb repressive complex
		BCR	Unknown	24388756	Open Targets	Pathways in cancer Chronic myeloid leukemia Signaling by cytosolic FGFR1 fusion mutants +2 more
		BIRC3	Unknown	30802265 23297126	Open Targets	Platinum drug resistance NF-kappa B signaling pathway Ubiquitin mediated proteolysis +23 more
		BIRC6	Unknown	24388756	Open Targets	Ubiquitin mediated proteolysis Autophagy - animal Apoptosis - multiple species
		BRAF	Unknown	30802265 28481359	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +52 more
		BRCA1	Unknown	27325104	Open Targets	Platinum drug resistance Homologous recombination Fanconi anemia pathway +19 more
		BTG1	Unknown	30802265 37333831	Open Targets	RNA degradation FOXO-mediated transcription of cell cycle genes
		BTG2	Unknown	24388756	Open Targets	RNA degradation TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain
		BTK	Unknown	30802265 28481359	Open Targets	NF-kappa B signaling pathway Osteoclast differentiation Platelet activation +17 more
		CALR	Unknown	23297126	Open Targets	Protein processing in endoplasmic reticulum Phagosome Efferocytosis +14 more
		CARD11	Unknown	30802265 24388756 26647218 28481359 21796119	Open Targets	NF-kappa B signaling pathway T cell receptor signaling pathway B cell receptor signaling pathway +4 more
		CARS1	Unknown	27325104	Open Targets	Aminoacyl-tRNA biosynthesis Cytosolic tRNA aminoacylation
		CBL	Unknown	24388756 28481359	Open Targets	ErbB signaling pathway Ubiquitin mediated proteolysis Endocytosis +22 more
		CCND3	Unknown	21796119	Open Targets	Cell cycle p53 signaling pathway PI3K-Akt signaling pathway +17 more
		CD274	Unknown	28481359	Open Targets	Cell adhesion molecules PD-L1 expression and PD-1 checkpoint pathway in cancer PD-1 signaling
		CD74	Unknown	27325104	Open Targets	Antigen processing and presentation Tuberculosis Herpes simplex virus 1 infection +2 more
		CD79A	Unknown	28481359	Open Targets	B cell receptor signaling pathway Primary immunodeficiency CD22 mediated BCR regulation +1 more
		CD79B	Unknown	30802265 24388756	Open Targets	B cell receptor signaling pathway CD22 mediated BCR regulation Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
		CDH10	Unknown	23297126	Open Targets	Adherens junctions interactions
		CDKN2A	Unknown	11021747 27566247 7670111 24449825 9531609	Open Targets	Endocrine resistance Platinum drug resistance Cell cycle +33 more
		CEBPA	Unknown	28481359	Open Targets	Non-alcoholic fatty liver disease Pathways in cancer Transcriptional misregulation in cancer +3 more
		CIITA	Unknown	30802265	Open Targets	Antigen processing and presentation Toxoplasmosis Tuberculosis +3 more
		CLTC	Unknown	23297126 24388756	Open Targets	Lysosome Endocytosis Synaptic vesicle cycle +18 more
		CNOT3	Unknown	27325104	Open Targets	RNA degradation Deadenylation of mRNA TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain
		CNTNAP2	Unknown	24388756	Open Targets	Cell adhesion molecules
		CPEB3	Unknown	27325104	Open Targets	Oocyte meiosis Progesterone-mediated oocyte maturation

«‹12 3 4 ›»

Neoplasm of mature b-cells

Bookmark This Disease