Subtype of: Mucoepidermoid carcinoma · Salivary gland mucoepidermoid carcinoma

Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
mucoepidermoid carcinoma of parotid gland	MONDO_0021280	ABL1	Unknown	27340278	Open Targets	ErbB signaling pathway Ras signaling pathway Cell cycle +17 more
		AFDN	Unknown	34011559	Open Targets	Ras signaling pathway Rap1 signaling pathway cAMP signaling pathway +4 more
		AKAP9	Unknown	27340278	Open Targets	Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes +7 more
		AR	Unknown	34098386 27340278	Open Targets	Oocyte meiosis Pathways in cancer Chemical carcinogenesis - receptor activation +7 more
		ARID2	Unknown	34098386	Open Targets	ATP-dependent chromatin remodeling Hepatocellular carcinoma RMTs methylate histone arginines +1 more
		BAP1	Unknown	34011559	Open Targets	Polycomb repressive complex UCH proteinases Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
		BCL11A	Unknown	27340278	Open Targets	—
		BCLAF1	Unknown	27340278	Open Targets	—
		BIRC6	Unknown	34011559	Open Targets	Ubiquitin mediated proteolysis Autophagy - animal Apoptosis - multiple species
		BMPR1A	Unknown	34098386	Open Targets	Cytokine-cytokine receptor interaction Hormone signaling TGF-beta signaling pathway +4 more
		CBL	Unknown	34098386 27340278	Open Targets	ErbB signaling pathway Ubiquitin mediated proteolysis Endocytosis +22 more
		CDK12	Unknown	34011559	Open Targets	TP53 Regulates Transcription of DNA Repair Genes
		CDKN2A	Unknown	19827123	Open Targets	Endocrine resistance Platinum drug resistance Cell cycle +33 more
		CHD4	Unknown	27340278	Open Targets	ATP-dependent chromatin remodeling Human papillomavirus infection Viral carcinogenesis +5 more
		CIC	Unknown	34011559	Open Targets	Spinocerebellar ataxia
		CLTC	Unknown	34011559	Open Targets	Lysosome Endocytosis Synaptic vesicle cycle +18 more
		COL1A1	Unknown	34011559	Open Targets	PI3K-Akt signaling pathway Focal adhesion ECM-receptor interaction +26 more
		CRTC1	Unknown	18181164 19827123 19438452 19578770 14720503 21668476 12539049 17437281 15269296 16444749	Open Targets	Human T-cell leukemia virus 1 infection Transcriptional activation of mitochondrial biogenesis Circadian Clock
		CRTC3	Unknown	21668476 19749740	Open Targets	Human T-cell leukemia virus 1 infection Transcriptional activation of mitochondrial biogenesis Circadian Clock
		CTNND1	Unknown	27340278	Open Targets	Rap1 signaling pathway Adherens junction Leukocyte transendothelial migration +3 more
		DCC	Unknown	34011559	Open Targets	Axon guidance Pathways in cancer Colorectal cancer +3 more
		DCTN1	Unknown	27340278	Open Targets	Motor proteins Vasopressin-regulated water reabsorption Amyotrophic lateral sclerosis +15 more
		DICER1	Unknown	34098386	Open Targets	MicroRNAs in cancer MicroRNA (miRNA) biogenesis Small interfering RNA (siRNA) biogenesis
		EGFR	Unknown	18542074 19362042	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Virion - Hepatitis viruses +79 more
		ERBB2	Unknown	34011559	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Platinum drug resistance +48 more
		ERBB4	Unknown	27340278	Open Targets	MAPK signaling pathway ErbB signaling pathway Calcium signaling pathway +22 more
		ETNK1	Unknown	27340278	Open Targets	Glycerophospholipid metabolism Metabolic pathways Synthesis of PE
		EWSR1	Unknown	18338330	Open Targets	Transcriptional misregulation in cancer
		FAT1	Unknown	34098386	Open Targets	—
		FBXO11	Unknown	34098386	Open Targets	Neddylation Antigen processing: Ubiquitination & Proteasome degradation
		FBXW7	Unknown	27340278	Open Targets	Ubiquitin mediated proteolysis Constitutive Signaling by NOTCH1 PEST Domain Mutants Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling +3 more
		FH	Unknown	27340278	Open Targets	Citrate cycle (TCA cycle) Pyruvate metabolism Metabolic pathways +5 more
		GPC5	Unknown	27340278	Open Targets	A tetrasaccharide linker sequence is required for GAG synthesis HS-GAG biosynthesis HS-GAG degradation +7 more
		H3C2	Unknown	34098386	Open Targets	Neutrophil extracellular trap formation Alcoholism Shigellosis +27 more
		HNF1A	Unknown	27340278	Open Targets	Maturity onset diabetes of the young
		HRAS	Unknown	32557577 10649241 34098386 27340278	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +134 more
		KAT6A	Unknown	27340278	Open Targets	Signaling pathways regulating pluripotency of stem cells HATs acetylate histones Regulation of TP53 Activity through Acetylation
		KAT6B	Unknown	27340278	Open Targets	HATs acetylate histones
		KIT	Unknown	34011559	Open Targets	MAPK signaling pathway Ras signaling pathway Rap1 signaling pathway +15 more
		KMT2C	Unknown	27340278	Open Targets	Lysine degradation Metabolic pathways PKMTs methylate histone lysines +1 more
		MAML2	Unknown	18181164 19827123 19438452 19578770 14720503 21668476 19749740 12539049 17437281 15269296 16444749	Open Targets	Notch signaling pathway Th1 and Th2 cell differentiation Human papillomavirus infection +9 more
		MSH2	Unknown	27340278	Open Targets	Platinum drug resistance Mismatch repair Pathways in cancer +7 more
		MSH6	Unknown	34098386	Open Targets	Platinum drug resistance Mismatch repair Pathways in cancer +4 more
		MUC16	Unknown	34011559	Open Targets	Defective GALNT3 causes familial hyperphosphatemic tumoral calcinosis (HFTC) Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS) Defective GALNT12 causes colorectal cancer 1 (CRCS1) +3 more
		MYH11	Unknown	27340278	Open Targets	Virion - Lassa virus and SFTS virus Vascular smooth muscle contraction Tight junction +6 more
		NCOA1	Unknown	27340278	Open Targets	Estrogen signaling pathway Thyroid hormone signaling pathway Pathways in cancer +18 more
		NDRG1	Unknown	27340278	Open Targets	TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain
		NIN	Unknown	27340278	Open Targets	—
		PABPC1	Unknown	27340278	Open Targets	mRNA surveillance pathway RNA degradation L13a-mediated translational silencing of Ceruloplasmin expression +5 more
		PBRM1	Unknown	27340278	Open Targets	ATP-dependent chromatin remodeling Hepatocellular carcinoma RMTs methylate histone arginines +1 more

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Mucoepidermoid carcinoma of parotid gland

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