Subtype of: Epithelial ovarian carcinoma

Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
Malignant Ovarian Mixed Epithelial Tumor	EFO_1000358	APC	Unknown	28481359	Open Targets	Wnt signaling pathway Hippo signaling pathway Signaling pathways regulating pluripotency of stem cells +28 more
		ARID1A	Unknown	28481359	Open Targets	ATP-dependent chromatin remodeling Thermogenesis Hepatocellular carcinoma +2 more
		ATM	Unknown	25846551	Open Targets	Platinum drug resistance Homologous recombination NF-kappa B signaling pathway +33 more
		ATR	Unknown	25846551	Open Targets	Fanconi anemia pathway Cell cycle p53 signaling pathway +13 more
		AXIN2	Unknown	28481359	Open Targets	Wnt signaling pathway Hippo signaling pathway Signaling pathways regulating pluripotency of stem cells +15 more
		BCL2	Unknown	28481359	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Platinum drug resistance +46 more
		BRCA1	Unknown	25846551 28481359 7795652	Open Targets	Platinum drug resistance Homologous recombination Fanconi anemia pathway +19 more
		BRCA2	Unknown	25846551 8665505 31538426	Open Targets	Homologous recombination Fanconi anemia pathway Pathways in cancer +7 more
		CDK12	Unknown	25846551	Open Targets	TP53 Regulates Transcription of DNA Repair Genes
		CDKN2A	Unknown	28481359	Open Targets	Endocrine resistance Platinum drug resistance Cell cycle +33 more
		CHEK2	Unknown	25846551	Open Targets	Cell cycle p53 signaling pathway Cellular senescence +9 more
		CTNNB1	Unknown	15668893 36384753	Open Targets	Rap1 signaling pathway Wnt signaling pathway Hippo signaling pathway +51 more
		DICER1	Unknown	28481359	Open Targets	MicroRNAs in cancer MicroRNA (miRNA) biogenesis Small interfering RNA (siRNA) biogenesis
		H3C2	Unknown	28481359	Open Targets	Neutrophil extracellular trap formation Alcoholism Shigellosis +27 more
		JUN	Unknown	28481359	Open Targets	Endocrine resistance MAPK signaling pathway ErbB signaling pathway +63 more
		KMT2D	Unknown	28481359	Open Targets	Lysine degradation Metabolic pathways Cushing syndrome +4 more
		KRAS	Unknown	36384753 24557434 31538426 8384077 32616873 28481359	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +134 more
		LATS1	Unknown	28481359	Open Targets	Hippo signaling pathway Hippo signaling pathway - multiple species Signaling by Hippo
		MAP2K1	Unknown	28481359	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +99 more
		NCOA2	Unknown	32616873	Open Targets	Estrogen signaling pathway Thyroid hormone signaling pathway RORA activates gene expression +14 more
		NF1	Unknown	28481359	Open Targets	EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway Ras signaling pathway +2 more
		NSD1	Unknown	28481359	Open Targets	Lysine degradation Metabolic pathways PKMTs methylate histone lysines
		NTRK3	Unknown	32616873	Open Targets	Calcium signaling pathway Neurotrophin signaling pathway Central carbon metabolism in cancer +4 more
		PIK3CA	Unknown	31538426 32616873 28481359 36384753	Open Targets	Inositol phosphate metabolism Metabolic pathways EGFR tyrosine kinase inhibitor resistance +149 more
		PIK3CB	Unknown	28481359	Open Targets	Inositol phosphate metabolism Metabolic pathways EGFR tyrosine kinase inhibitor resistance +126 more
		PTCH1	Unknown	28481359	Open Targets	cAMP signaling pathway Hedgehog signaling pathway Axon guidance +7 more
		PTEN	Unknown	15668893 28481359	Open Targets	Inositol phosphate metabolism Metabolic pathways EGFR tyrosine kinase inhibitor resistance +37 more
		RASA1	Unknown	28481359	Open Targets	MAPK signaling pathway Ras signaling pathway Axon guidance +5 more
		SRC	Unknown	28481359	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance ErbB signaling pathway +92 more
		TERT	Unknown	28481359	Open Targets	Human papillomavirus infection Human T-cell leukemia virus 1 infection Pathways in cancer +4 more
		TP53	Unknown	25846551 11595686 36384753 31472684 15099937 16211227 28481359	Open Targets	Endocrine resistance Platinum drug resistance MAPK signaling pathway +85 more

Malignant ovarian mixed epithelial tumor

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