Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
CHRONIC LYMPHOCYTIC LEUKEMIA	EFO_0000095	HLA-DRB1	Unknown	21131588 26956414 28165464	GWAS catalog	Phagosome Cell adhesion molecules Antigen processing and presentation +28 more
		HYCC2	Unknown	26956414	GWAS catalog	—
		ILRUN	Unknown	28165464	GWAS catalog	—
		IPCEF1	Unknown	24292274 40883272	GWAS catalog	—
		IRF4	Unknown	18758461 21131588 22700719 23770605 24292274 26956414 28112199 28165464 34290314 39024449	GWAS catalog	Th17 cell differentiation Interleukin-4 and Interleukin-13 signaling Interferon gamma signaling +1 more
		IRF8	Unknown	21131588 23770605 24292274 26956414 28165464 39024449	GWAS catalog	Pertussis Interferon gamma signaling Interferon alpha/beta signaling
		JARID2	Unknown	40883272	GWAS catalog	Polycomb repressive complex Signaling pathways regulating pluripotency of stem cells PRC2 methylates histones and DNA
		KIF18A	Unknown	34290314	GWAS catalog	Motor proteins Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal MHC class II antigen presentation +7 more
		KPNA7	Unknown	34290314	GWAS catalog	Nucleocytoplasmic transport Influenza A Chemical carcinogenesis - receptor activation +2 more
		KRT32	Unknown	34290314	GWAS catalog	Estrogen signaling pathway Staphylococcus aureus infection Keratinization +1 more
		LEF1	Unknown	23770605 26956414 28165464 40883272	GWAS catalog	Wnt signaling pathway Hippo signaling pathway Adherens junction +24 more
		LHFPL3	Unknown	34290314	GWAS catalog	—
		LPP	Unknown	26956414 28112199 28165464 40883272	GWAS catalog	—
		LRRC34	Unknown	31407831	GWAS catalog	—
		MAP1LC3B2	Unknown	40883272	GWAS catalog	Mitophagy - animal Autophagy - animal Ferroptosis +6 more
		MAP2K2	Unknown	28165464	GWAS catalog	EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +87 more
		MAST4	Unknown	34290314	GWAS catalog	—
		MC4R	Unknown	34290314	GWAS catalog	Neuroactive ligand-receptor interaction Hormone signaling Peptide ligand-binding receptors +2 more
		METTL15	Unknown	34290314	GWAS catalog	—
		MGAT5	Unknown	31407831	GWAS catalog	N-Glycan biosynthesis Metabolic pathways N-Glycan antennae elongation
		MNS1	Unknown	23770605 26956414 28165464	GWAS catalog	—
		MRPL15	Unknown	34290314	GWAS catalog	Ribosome Mitochondrial translation elongation Mitochondrial translation termination
		MYNN	Unknown	24292274 31407831 39024449	GWAS catalog	—
		NCAPH2	Unknown	28112199 40883272	GWAS catalog	Condensation of Prophase Chromosomes
		NCK1	Unknown	28112199	GWAS catalog	ErbB signaling pathway Axon guidance T cell receptor signaling pathway +10 more
		NDUFAF7	Unknown	24292274	GWAS catalog	Thermogenesis Complex I biogenesis
		NT5C1A	Unknown	40883272	GWAS catalog	Purine metabolism Pyrimidine metabolism Nicotinate and nicotinamide metabolism +4 more
		OAS3	Unknown	28165464	GWAS catalog	NOD-like receptor signaling pathway Hepatitis C Measles +7 more
		ODF1	Unknown	23770605 26956414 28165464 40883272	GWAS catalog	—
		OPRM1	Unknown	24292274 28165464	GWAS catalog	Neuroactive ligand-receptor interaction Hormone signaling Estrogen signaling pathway +6 more
		OR6V1	Unknown	34290314	GWAS catalog	Olfactory transduction Olfactory Signaling Pathway
		ORC5	Unknown	34290314	GWAS catalog	Cell cycle Activation of ATR in response to replication stress Assembly of the ORC complex at the origin of replication +5 more
		PALD1	Unknown	40883272	GWAS catalog	—
		PHLPP1	Unknown	28165464	GWAS catalog	PI3K-Akt signaling pathway Negative regulation of the PI3K/AKT network
		PISD	Unknown	34290314	GWAS catalog	Glycerophospholipid metabolism Metabolic pathways
		POT1	Unknown	24292274	GWAS catalog	Recognition and association of DNA glycosylase with site containing an affected purine Cleavage of the damaged purine Packaging Of Telomere Ends +2 more
		PRKD2	Unknown	18758461	GWAS catalog	Rap1 signaling pathway Aldosterone synthesis and secretion Chemical carcinogenesis - reactive oxygen species +1 more
		PTPRK	Unknown	31407831	GWAS catalog	EGFR downregulation
		QPCT	Unknown	26956414 28165464	GWAS catalog	Neutrophil degranulation
		RFX7	Unknown	24292274 40883272	GWAS catalog	—
		RHOU	Unknown	28165464	GWAS catalog	Rho GTPase cycle Interleukin-4 and Interleukin-13 signaling
		RNF39	Unknown	26956414	GWAS catalog	—
		RPL39L	Unknown	34290314	GWAS catalog	L13a-mediated translational silencing of Ceruloplasmin expression SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation +5 more
		RPS6KB1	Unknown	31407831	GWAS catalog	EGFR tyrosine kinase inhibitor resistance Endocrine resistance ErbB signaling pathway +29 more
		RREB1	Unknown	31407831	GWAS catalog	—
		SAE1	Unknown	40883272	GWAS catalog	Ubiquitin mediated proteolysis SUMO is conjugated to E1 (UBA2:SAE1) SUMO is transferred from E1 to E2 (UBE2I, UBC9)
		SEC23IP	Unknown	34290314	GWAS catalog	COPII-mediated vesicle transport
		SEPTIN2	Unknown	28165464	GWAS catalog	Bacterial invasion of epithelial cells Shigellosis Anchoring of the basal body to the plasma membrane
		SERINC2	Unknown	28112199	GWAS catalog	Serine biosynthesis
		SERPINB6	Unknown	26956414	GWAS catalog	Amoebiasis Neutrophil degranulation Dissolution of Fibrin Clot

«‹123 ›»

Lymphocytic leukemia

Bookmark This Disease