Subtype of: Lung cancer

Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
lung inflammatory myofibroblastic tumor	MONDO_0006276	ABL1	Unknown	33200540	Open Targets	ErbB signaling pathway Ras signaling pathway Cell cycle +17 more
		ACSL3	Unknown	33200540	Open Targets	Fatty acid biosynthesis Fatty acid degradation Metabolic pathways +8 more
		AFF1	Unknown	33200540	Open Targets	Transcriptional misregulation in cancer
		ALK	Unknown	17063337 23957430 21430068 10934142 16984614 33200540	Open Targets	Pathways in cancer Non-small cell lung cancer PD-L1 expression and PD-1 checkpoint pathway in cancer
		AMER1	Unknown	33200540	Open Targets	Degradation of beta-catenin by the destruction complex Beta-catenin phosphorylation cascade Disassembly of the destruction complex and recruitment of AXIN to the membrane +8 more
		ARID1A	Unknown	33200540	Open Targets	ATP-dependent chromatin remodeling Thermogenesis Hepatocellular carcinoma +2 more
		ARNT	Unknown	33200540	Open Targets	HIF-1 signaling pathway Efferocytosis Cushing syndrome +10 more
		ATF1	Unknown	33200540	Open Targets	Aldosterone synthesis and secretion Transcriptional misregulation in cancer CREB phosphorylation +1 more
		ATM	Unknown	33200540	Open Targets	Platinum drug resistance Homologous recombination NF-kappa B signaling pathway +33 more
		AXIN1	Unknown	33200540	Open Targets	Wnt signaling pathway Hippo signaling pathway Signaling pathways regulating pluripotency of stem cells +28 more
		BIRC3	Unknown	33200540	Open Targets	Platinum drug resistance NF-kappa B signaling pathway Ubiquitin mediated proteolysis +23 more
		BRCA1	Unknown	33200540	Open Targets	Platinum drug resistance Homologous recombination Fanconi anemia pathway +19 more
		CHEK2	Unknown	33200540	Open Targets	Cell cycle p53 signaling pathway Cellular senescence +9 more
		CLTC	Unknown	16984614	Open Targets	Lysosome Endocytosis Synaptic vesicle cycle +18 more
		DICER1	Unknown	33200540	Open Targets	MicroRNAs in cancer MicroRNA (miRNA) biogenesis Small interfering RNA (siRNA) biogenesis
		EML4	Unknown	33200540	Open Targets	Pathways in cancer Non-small cell lung cancer PD-L1 expression and PD-1 checkpoint pathway in cancer +1 more
		EPHA7	Unknown	33200540	Open Targets	Axon guidance EPH-Ephrin signaling EPHA-mediated growth cone collapse +1 more
		ERG	Unknown	33200540	Open Targets	Transcriptional misregulation in cancer Prostate cancer
		ETV6	Unknown	10895816	Open Targets	Transcriptional misregulation in cancer Signaling by membrane-tethered fusions of PDGFRA or PDGFRB
		HIF1A	Unknown	33200540	Open Targets	HIF-1 signaling pathway Mitophagy - animal Autophagy - animal +19 more
		HLF	Unknown	33200540	Open Targets	—
		HSP90AA1	Unknown	33200540	Open Targets	Protein processing in endoplasmic reticulum PI3K-Akt signaling pathway Necroptosis +56 more
		JAK2	Unknown	33200540	Open Targets	EGFR tyrosine kinase inhibitor resistance Chemokine signaling pathway Hormone signaling +51 more
		KAT6A	Unknown	33200540	Open Targets	Signaling pathways regulating pluripotency of stem cells HATs acetylate histones Regulation of TP53 Activity through Acetylation
		KAT6B	Unknown	33200540	Open Targets	HATs acetylate histones
		KDR	Unknown	33200540	Open Targets	EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway Ras signaling pathway +13 more
		KIT	Unknown	33200540	Open Targets	MAPK signaling pathway Ras signaling pathway Rap1 signaling pathway +15 more
		KMT2C	Unknown	33200540	Open Targets	Lysine degradation Metabolic pathways PKMTs methylate histone lysines +1 more
		LCK	Unknown	33200540	Open Targets	NF-kappa B signaling pathway Osteoclast differentiation Natural killer cell mediated cytotoxicity +27 more
		MEN1	Unknown	33200540	Open Targets	Cushing syndrome Transcriptional misregulation in cancer Formation of the beta-catenin:TCF transactivating complex +5 more
		MYC	Unknown	33200540	Open Targets	MAPK signaling pathway ErbB signaling pathway Cell cycle +45 more
		MYCN	Unknown	33200540	Open Targets	Transcriptional misregulation in cancer
		MYH11	Unknown	33200540	Open Targets	Virion - Lassa virus and SFTS virus Vascular smooth muscle contraction Tight junction +6 more
		NCOA1	Unknown	33200540	Open Targets	Estrogen signaling pathway Thyroid hormone signaling pathway Pathways in cancer +18 more
		NIN	Unknown	33200540	Open Targets	—
		NOTCH2	Unknown	33200540	Open Targets	Endocrine resistance Notch signaling pathway Th1 and Th2 cell differentiation +13 more
		NSD2	Unknown	33200540	Open Targets	Lysine degradation Metabolic pathways Transcriptional misregulation in cancer +5 more
		NTRK3	Unknown	10895816	Open Targets	Calcium signaling pathway Neurotrophin signaling pathway Central carbon metabolism in cancer +4 more
		NUMA1	Unknown	33200540	Open Targets	Recruitment of NuMA to mitotic centrosomes Mitotic Prophase
		NUP214	Unknown	33200540	Open Targets	Nucleocytoplasmic transport Amyotrophic lateral sclerosis ISG15 antiviral mechanism +26 more
		PMS1	Unknown	33200540	Open Targets	—
		POLE	Unknown	33200540	Open Targets	DNA replication Base excision repair Nucleotide excision repair +10 more
		PPFIBP1	Unknown	23957430 21430068	Open Targets	Receptor-type tyrosine-protein phosphatases
		PTPRD	Unknown	33200540	Open Targets	Cell adhesion molecules Receptor-type tyrosine-protein phosphatases Synaptic adhesion-like molecules
		PTPRK	Unknown	33200540	Open Targets	EGFR downregulation
		RAD51D	Unknown	33200540	Open Targets	Homologous recombination HDR through Homologous Recombination (HRR) Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) +4 more
		SEPTIN9	Unknown	33200540	Open Targets	Bacterial invasion of epithelial cells Shigellosis
		SMARCD1	Unknown	33200540	Open Targets	ATP-dependent chromatin remodeling Thermogenesis Hepatocellular carcinoma +2 more
		SOS1	Unknown	33200540	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +97 more
		SPOP	Unknown	33200540	Open Targets	Hedgehog signaling pathway Hedgehog 'on' state

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Lung inflammatory myofibroblastic tumor

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