Long qt syndrome

cAMP signaling pathway Taste transduction HCN channels

PPAR signaling pathway Axon guidance Focal adhesion Bacterial invasion of epithelial cells Shigellosis Endometrial cancer Localization of the PINCH-ILK-PARVIN complex to focal adhesions Cell-extracellular matrix interactions +5 more

Cytoskeleton in muscle cells Pathways in cancer Transcriptional misregulation in cancer Acute myeloid leukemia Gastric cancer Arrhythmogenic right ventricular cardiomyopathy Adherens junctions interactions VEGFR2 mediated vascular permeability Neutrophil degranulation Keratinization Formation of the cornified envelope +8 more

Protein digestion and absorption Phase 3 - rapid repolarisation Phase 2 - plateau phase

cGMP-PKG signaling pathway ATP sensitive Potassium channels

Motor proteins COPI-dependent Golgi-to-ER retrograde traffic Kinesins

Cytoskeleton in muscle cells

cGMP-PKG signaling pathway Cardiac muscle contraction Adrenergic signaling in cardiomyocytes Motor proteins Cytoskeleton in muscle cells Thyroid hormone signaling pathway Hypertrophic cardiomyopathy Dilated cardiomyopathy Viral myocarditis +6 more

Cardiac muscle contraction Adrenergic signaling in cardiomyocytes Apelin signaling pathway Motor proteins Cytoskeleton in muscle cells Hypertrophic cardiomyopathy Dilated cardiomyopathy Striated Muscle Contraction +5 more

YAP1- and WWTR1 (TAZ)-stimulated gene expression Physiological factors

Inositol phosphate metabolism Metabolic pathways Phosphatidylinositol signaling system Synthesis of PIPs at the ER membrane Synthesis of PIPs at the Golgi membrane +2 more

Inositol phosphate metabolism Metabolic pathways cGMP-PKG signaling pathway Chemokine signaling pathway Phospholipase D signaling pathway PI3K-Akt signaling pathway Adrenergic signaling in cardiomyocytes Apelin signaling pathway Platelet activation Cholinergic synapse Oxytocin signaling pathway Salmonella infection Toxoplasmosis Kaposi sarcoma-associated herpesvirus infection GPVI-mediated activation cascade Synthesis of PIPs at the plasma membrane G beta:gamma signalling through PI3Kgamma Erythropoietin activates Phosphoinositide-3-kinase (PI3K) +15 more

Cytoskeleton in muscle cells Arrhythmogenic right ventricular cardiomyopathy Keratinization Formation of the cornified envelope +1 more

cAMP signaling pathway Neuroactive ligand-receptor interaction Hormone signaling Estrogen signaling pathway Melanogenesis Adipocytokine signaling pathway Aldosterone synthesis and secretion Cortisol synthesis and secretion Cushing syndrome Opioid Signalling Androgen biosynthesis Glucocorticoid biosynthesis G-protein activation Peptide hormone biosynthesis Endogenous sterols Peptide ligand-binding receptors G alpha (s) signalling events G alpha (i) signalling events Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Interleukin-4 and Interleukin-13 signaling ADORA2B mediated anti-inflammatory cytokines production +18 more

Inositol phosphate metabolism Metabolic pathways EGFR tyrosine kinase inhibitor resistance FoxO signaling pathway Phosphatidylinositol signaling system Sphingolipid signaling pathway p53 signaling pathway Autophagy - animal mTOR signaling pathway PI3K-Akt signaling pathway Cellular senescence Focal adhesion Insulin resistance Human papillomavirus infection Human T-cell leukemia virus 1 infection Pathways in cancer MicroRNAs in cancer Chemical carcinogenesis - reactive oxygen species Endometrial cancer Glioma Prostate cancer Melanoma Small cell lung cancer Breast cancer Hepatocellular carcinoma Central carbon metabolism in cancer PD-L1 expression and PD-1 checkpoint pathway in cancer Diabetic cardiomyopathy Synthesis of PIPs at the plasma membrane Synthesis of IP3 and IP4 in the cytosol Negative regulation of the PI3K/AKT network Downstream TCR signaling TP53 Regulates Metabolic Genes PTEN Loss of Function in Cancer Ub-specific processing proteases Ovarian tumor domain proteases Regulation of PTEN mRNA translation Regulation of PTEN localization Regulation of PTEN stability and activity Transcriptional Regulation by MECP2 +37 more

Synaptic vesicle cycle Retrograde endocannabinoid signaling Serotonin Neurotransmitter Release Cycle Norepinephrine Neurotransmitter Release Cycle Glutamate Neurotransmitter Release Cycle Dopamine Neurotransmitter Release Cycle Acetylcholine Neurotransmitter Release Cycle GABA synthesis, release, reuptake and degradation +5 more

Calcium signaling pathway Apelin signaling pathway Circadian entrainment Long-term depression Oxytocin signaling pathway Spinocerebellar ataxia Prion disease Pathways of neurodegeneration - multiple diseases Stimuli-sensing channels Ion homeostasis +7 more

Adrenergic signaling in cardiomyocytes Phase 0 - rapid depolarisation

Phase 0 - rapid depolarisation

Phase 0 - rapid depolarisation

Nicotinate and nicotinamide metabolism Metabolic pathways Thermogenesis Central carbon metabolism in cancer Processing of DNA double-strand break ends +2 more

Carbohydrate digestion and absorption Neutrophil degranulation Intestinal hexose absorption

Cytoskeleton in muscle cells

Basal transcription factors Ub-specific processing proteases RNA Polymerase II Pre-transcription Events Regulation of TP53 Activity through Phosphorylation RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance +5 more

Synthesis of very long-chain fatty acyl-CoAs

MAPK signaling pathway Cytokine-cytokine receptor interaction FoxO signaling pathway Cell cycle Cellular senescence TGF-beta signaling pathway Hippo signaling pathway AGE-RAGE signaling pathway in diabetic complications Leishmaniasis Chagas disease Malaria Toxoplasmosis Amoebiasis Tuberculosis Hepatitis B Human T-cell leukemia virus 1 infection Pathways in cancer Colorectal cancer Renal cell carcinoma Pancreatic cancer Chronic myeloid leukemia Hepatocellular carcinoma Gastric cancer Inflammatory bowel disease Rheumatoid arthritis Hypertrophic cardiomyopathy Dilated cardiomyopathy Diabetic cardiomyopathy Platelet degranulation Molecules associated with elastic fibres +27 more

Cytoskeleton in muscle cells

Nuclear Envelope Breakdown Initiation of Nuclear Envelope (NE) Reformation Depolymerisation of the Nuclear Lamina

cAMP signaling pathway Cardiac muscle contraction Adrenergic signaling in cardiomyocytes Motor proteins Cytoskeleton in muscle cells Hypertrophic cardiomyopathy Dilated cardiomyopathy Diabetic cardiomyopathy Striated Muscle Contraction Ion homeostasis +7 more

Insulin secretion TRP channels

Human papillomavirus infection Viral carcinogenesis Neutrophil degranulation Antigen processing: Ubiquitination & Proteasome degradation +1 more

Ubiquitin mediated proteolysis

Focal adhesion Adherens junction Leukocyte transendothelial migration Regulation of actin cytoskeleton Cytoskeleton in muscle cells Bacterial invasion of epithelial cells Shigellosis Amoebiasis Platelet degranulation Smooth Muscle Contraction MAP2K and MAPK activation Neutrophil degranulation Signaling by moderate kinase activity BRAF mutants Signaling by high-kinase activity BRAF mutants Signaling by BRAF and RAF fusions Paradoxical activation of RAF signaling by kinase inactive BRAF Signaling downstream of RAS mutants +14 more

N-Glycan biosynthesis Metabolic pathways

Retinoid metabolism and transport

Ras signaling pathway Rap1 signaling pathway Calcium signaling pathway cGMP-PKG signaling pathway cAMP signaling pathway Phosphatidylinositol signaling system Oocyte meiosis Cellular senescence Adrenergic signaling in cardiomyocytes Vascular smooth muscle contraction Apelin signaling pathway C-type lectin receptor signaling pathway Circadian entrainment Long-term potentiation Neurotrophin signaling pathway Dopaminergic synapse Olfactory transduction Phototransduction Inflammatory mediator regulation of TRP channels Insulin signaling pathway GnRH signaling pathway Estrogen signaling pathway Melanogenesis Oxytocin signaling pathway Glucagon signaling pathway Renin secretion Aldosterone synthesis and secretion Salivary secretion Gastric acid secretion Alzheimer disease Parkinson disease Pathways of neurodegeneration - multiple diseases Amphetamine addiction Alcoholism Pertussis Tuberculosis Human cytomegalovirus infection Kaposi sarcoma-associated herpesvirus infection Human immunodeficiency virus 1 infection Pathways in cancer Glioma Lipid and atherosclerosis Fluid shear stress and atherosclerosis CaMK IV-mediated phosphorylation of CREB Calmodulin induced events Cam-PDE 1 activation Platelet degranulation Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation PKA activation Synthesis of IP3 and IP4 in the cytosol Calcineurin activates NFAT eNOS activation Inactivation, recovery and regulation of the phototransduction cascade Stimuli-sensing channels FCERI mediated Ca+2 mobilization Ca2+ pathway Reduction of cytosolic Ca++ levels Sodium/Calcium exchangers Unblocking of NMDA receptors, glutamate binding and activation CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde Smooth Muscle Contraction Activation of Ca-permeable Kainate Receptor Uptake and function of anthrax toxins VEGFR2 mediated vascular permeability Phase 0 - rapid depolarisation Ion homeostasis CLEC7A (Dectin-1) induces NFAT activation RHO GTPases activate IQGAPs RHO GTPases activate PAKs RAF activation RAF/MAP kinase cascade Signaling by moderate kinase activity BRAF mutants Signaling by BRAF and RAF fusions Paradoxical activation of RAF signaling by kinase inactive BRAF Glycogen breakdown (glycogenolysis) Protein methylation Extra-nuclear estrogen signaling Ion transport by P-type ATPases Activation of RAC1 downstream of NMDARs Long-term potentiation Signaling downstream of RAS mutants FCGR3A-mediated IL10 synthesis +79 more

Cytoskeleton in muscle cells Arrhythmogenic right ventricular cardiomyopathy Apoptotic cleavage of cell adhesion proteins Neutrophil degranulation Keratinization Formation of the cornified envelope +3 more

Cytoskeleton in muscle cells Arrhythmogenic right ventricular cardiomyopathy Keratinization Formation of the cornified envelope +1 more

Calcium signaling pathway cAMP signaling pathway Cardiac muscle contraction Adrenergic signaling in cardiomyocytes Apelin signaling pathway Circadian entrainment Insulin secretion Oxytocin signaling pathway Pancreatic secretion Prion disease Pathways of neurodegeneration - multiple diseases Hypertrophic cardiomyopathy Arrhythmogenic right ventricular cardiomyopathy Dilated cardiomyopathy Diabetic cardiomyopathy Stimuli-sensing channels Ion homeostasis +14 more

YAP1- and WWTR1 (TAZ)-stimulated gene expression Physiological factors