Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
LEWY BODY DEMENTIA	EFO_0006792 MONDO:0007488	GBA1	Causal	33589841 35381062 41068259	ClinVar, GWAS catalog	—
		SNCA	Causal	29263008 35729600	ClinVar, GWAS catalog, GenCC	Alzheimer disease Parkinson disease Pathways of neurodegeneration - multiple diseases +1 more
		SNCB	Causal	—	ClinVar, GenCC	MTF1 activates gene expression
		ABRA	Unknown	25188341	GWAS catalog	—
		ABTB2	Unknown	28322283	GWAS catalog	—
		ACADSB	Unknown	25188341	GWAS catalog	Fatty acid degradation Valine, leucine and isoleucine degradation Metabolic pathways +2 more
		APOC1	Unknown	35729600 40045203	GWAS catalog	Cholesterol metabolism VLDL assembly VLDL clearance +1 more
		APOE	Unknown	25188341 28322283 29263008 31065058 33589841 37700353 40374660 41068259	GWAS catalog	Cholesterol metabolism Alzheimer disease Nuclear signaling by ERBB4 +10 more
		ASH1L	Unknown	31065058	GWAS catalog	Lysine degradation Metabolic pathways PKMTs methylate histone lysines
		ATP10A	Unknown	28322283	GWAS catalog	Ion transport by P-type ATPases
		BCL7C	Unknown	29263008	GWAS catalog	ATP-dependent chromatin remodeling
		BICC1	Unknown	40045203	GWAS catalog	—
		BIN1	Unknown	33589841 35729600 37700353 41068259	GWAS catalog	Endocytosis Fc gamma R-mediated phagocytosis Clathrin-mediated endocytosis
		BLMH	Unknown	37700353	GWAS catalog	Antigen processing: Ubiquitination & Proteasome degradation
		BST1	Unknown	35729600	GWAS catalog	Nicotinate and nicotinamide metabolism Metabolic pathways Salivary secretion +4 more
		CDKAL1	Unknown	28322283	GWAS catalog	tRNA modification in the nucleus and cytosol
		CLU	Unknown	35729600	GWAS catalog	Complement and coagulation cascades Platelet degranulation Terminal pathway of complement +2 more
		CTNND2	Unknown	25188341	GWAS catalog	Wnt signaling pathway
		CTSV	Unknown	28322283	GWAS catalog	Lysosome Apoptosis Degradation of the extracellular matrix +5 more
		CYB5R4	Unknown	28322283	GWAS catalog	Biosynthesis of various nucleotide sugars Erythrocytes take up carbon dioxide and release oxygen
		DHTKD1	Unknown	40045203	GWAS catalog	Lysine degradation Tryptophan metabolism Lipoic acid metabolism +3 more
		ECHDC3	Unknown	35729600	GWAS catalog	—
		ELOVL7	Unknown	35729600	GWAS catalog	Fatty acid elongation Biosynthesis of unsaturated fatty acids Metabolic pathways +2 more
		FARS2	Unknown	28322283	GWAS catalog	Aminoacyl-tRNA biosynthesis Mitochondrial tRNA aminoacylation
		FDFT1	Unknown	35729600	GWAS catalog	Steroid biosynthesis Metabolic pathways Cholesterol biosynthesis +2 more
		FOXN3	Unknown	28322283	GWAS catalog	—
		FRMD3	Unknown	25188341	GWAS catalog	—
		GARNL3	Unknown	25188341	GWAS catalog	—
		HAVCR2	Unknown	35729600	GWAS catalog	Efferocytosis
		HMX3	Unknown	25188341	GWAS catalog	—
		HPS5	Unknown	25188341	GWAS catalog	—
		HRH1	Unknown	35381062	GWAS catalog	Calcium signaling pathway Neuroactive ligand-receptor interaction Inflammatory mediator regulation of TRP channels +2 more
		HS3ST4	Unknown	28322283	GWAS catalog	HS-GAG biosynthesis
		ICOS	Unknown	40045203	GWAS catalog	Cell adhesion molecules T cell receptor signaling pathway Intestinal immune network for IgA production +5 more
		INPP5F	Unknown	35729600	GWAS catalog	Inositol phosphate metabolism Metabolic pathways Phosphatidylinositol signaling system +1 more
		JPH3	Unknown	28322283	GWAS catalog	—
		KANSL1	Unknown	35729600	GWAS catalog	HATs acetylate histones
		KAZN	Unknown	28322283	GWAS catalog	Formation of the cornified envelope
		KCNB2	Unknown	28322283	GWAS catalog	Voltage gated Potassium channels
		KPNA4	Unknown	40045203	GWAS catalog	Nucleocytoplasmic transport Salmonella infection Chemical carcinogenesis - receptor activation +2 more
		KRTCAP2	Unknown	29263008	GWAS catalog	N-Glycan biosynthesis Various types of N-glycan biosynthesis Protein processing in endoplasmic reticulum
		MAP3K15	Unknown	38378815	GWAS catalog	—
		MCCC1	Unknown	35729600	GWAS catalog	Valine, leucine and isoleucine degradation Metabolic pathways Biotin transport and metabolism +2 more
		MS4A6A	Unknown	35729600	GWAS catalog	—
		MSR1	Unknown	35729600	GWAS catalog	Phagosome Scavenging by Class A Receptors
		MYO7A	Unknown	25188341	GWAS catalog	Motor proteins The canonical retinoid cycle in rods (twilight vision)
		NCOR1	Unknown	35729600	GWAS catalog	Endocrine resistance TGF-beta signaling pathway Thyroid hormone signaling pathway +16 more
		NTS	Unknown	25188341	GWAS catalog	Neuroactive ligand-receptor interaction Peptide ligand-binding receptors G alpha (q) signalling events
		PARVB	Unknown	25188341	GWAS catalog	Focal adhesion Cell-extracellular matrix interactions Regulation of cytoskeletal remodeling and cell spreading by IPP complex components
		PDLIM5	Unknown	25188341	GWAS catalog	Cytoskeleton in muscle cells
LEWY BODY DISEASE	C0752347 MESH:D020961	GBA1	Unknown	22803570 33589841	CTD, Disgenet	—
		SNCA	Unknown	16141792 19628769	CTD, Disgenet	Alzheimer disease Parkinson disease Pathways of neurodegeneration - multiple diseases +1 more
		SNCB	Unknown	—	CTD, Disgenet	MTF1 activates gene expression

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Lewy body disease

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