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Leukodystrophy, adult-onset, autosomal dominant, without amyloid angiopathy
Leukodystrophy, adult-onset, autosomal dominant, without amyloid angiopathy
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Subtype of:
Leukodystrophy
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Pathways column key:
KEGG
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Disease terms
Disease ID
Gene Symbol
Classification
References
Source
Pathways
leukodystrophy, adult-onset, autosomal dominant, without amyloid angiopathy
MONDO_0008215
CST3
Unknown
—
ClinGen
Salivary secretion
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Neutrophil degranulation
Post-translational protein phosphorylation
Amyloid fiber formation
+2 more
leukodystrophy, adult-onset, autosomal dominant, without amyloid angiopathy
MONDO_0008215
LMNB1
Unknown
16951681
20301621
21225301
21909802
24357685
25527826
25655951
27159321
28334938
28716252
32910914
Open Targets
Apoptosis
Cytoskeleton in muscle cells
Formation of Senescence-Associated Heterochromatin Foci (SAHF)
Nuclear Envelope Breakdown
Initiation of Nuclear Envelope (NE) Reformation
Breakdown of the nuclear lamina
Depolymerisation of the Nuclear Lamina
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
+5 more
All
2
Causal
0
Unknown
2
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Clear
ClinVar
0
Orphanet
0
Disgenet
0
CTD
0
HPO
0
GWAS catalog
0
GenCC
0
ClinGen
1
Open Targets
1
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1 shared gene
CST3
Related via 1 shared gene including CST3.
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1 shared gene
LMNB1
Related via 1 shared gene including LMNB1.
Microcephaly 26, primary, autosomal dominant
1 shared gene
LMNB1
Related via 1 shared gene including LMNB1.
Oral submucous fibrosis
1 shared gene
CST3
Related via 1 shared gene including CST3.
Leukodystrophy
1 shared gene
CST3
Related via 1 shared gene including CST3.
1
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