Leber congenital amaurosis

Hippo signaling pathway

Purine metabolism Metabolic pathways Olfactory transduction Phototransduction Inactivation, recovery and regulation of the phototransduction cascade +2 more

Retinol metabolism Metabolic pathways Vitamin digestion and absorption Retinoid cycle disease events The canonical retinoid cycle in rods (twilight vision) Retinoid metabolism and transport +3 more

Transcriptional misregulation in cancer

Retinol metabolism Metabolic pathways The canonical retinoid cycle in rods (twilight vision)

Nicotinate and nicotinamide metabolism Metabolic pathways Biosynthesis of cofactors Nicotinate metabolism +1 more

Defective B3GALTL causes Peters-plus syndrome (PpS) O-glycosylation of TSR domain-containing proteins

Association of TriC/CCT with target proteins during biosynthesis BBSome-mediated cargo-targeting to cilium Neutrophil degranulation Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding +1 more

Cytokine-cytokine receptor interaction TGF-beta signaling pathway Hippo signaling pathway

Folate biosynthesis Metabolic pathways Biosynthesis of cofactors GABAergic synapse Molybdenum cofactor biosynthesis +2 more

Phototransduction Inactivation, recovery and regulation of the phototransduction cascade

Hedgehog 'off' state Intraflagellar transport

Purine metabolism Drug metabolism - other enzymes Metabolic pathways Nucleotide metabolism Neutrophil degranulation Purine ribonucleoside monophosphate biosynthesis +3 more

mTOR signaling pathway Wnt signaling pathway Parathyroid hormone synthesis, secretion and action Alzheimer disease Pathways of neurodegeneration - multiple diseases Pathways in cancer Breast cancer Hepatocellular carcinoma Gastric cancer Negative regulation of TCF-dependent signaling by WNT ligand antagonists Disassembly of the destruction complex and recruitment of AXIN to the membrane Regulation of FZD by ubiquitination Misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling RNF mutants show enhanced WNT signaling and proliferation +11 more

Motor proteins The canonical retinoid cycle in rods (twilight vision)

COPI-dependent Golgi-to-ER retrograde traffic

Anchoring of the basal body to the plasma membrane

Trafficking of myristoylated proteins to the cilium

Signaling by Hippo Anchoring of the basal body to the plasma membrane

Pantothenate and CoA biosynthesis Metabolic pathways Biosynthesis of cofactors Coenzyme A biosynthesis +1 more

Phosphonate and phosphinate metabolism Glycerophospholipid metabolism Metabolic pathways Choline metabolism in cancer Synthesis of PC +2 more

Spliceosome mRNA Splicing - Major Pathway

Retinoid cycle disease events The canonical retinoid cycle in rods (twilight vision) Retinoid metabolism and transport

Synaptic vesicle cycle Retrograde endocannabinoid signaling Serotonin Neurotransmitter Release Cycle Norepinephrine Neurotransmitter Release Cycle Glutamate Neurotransmitter Release Cycle Dopamine Neurotransmitter Release Cycle Acetylcholine Neurotransmitter Release Cycle GABA synthesis, release, reuptake and degradation +5 more

Hippo signaling pathway Hippo signaling pathway - multiple species YAP1- and WWTR1 (TAZ)-stimulated gene expression RUNX3 regulates YAP1-mediated transcription +1 more

BBSome-mediated cargo-targeting to cilium

Phagosome Gap junction Motor proteins Alzheimer disease Parkinson disease Amyotrophic lateral sclerosis Huntington disease Prion disease Pathways of neurodegeneration - multiple diseases Pathogenic Escherichia coli infection Salmonella infection Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane MHC class II antigen presentation Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Regulation of PLK1 Activity at G2/M Transition HSP90 chaperone cycle for steroid hormone receptors (SHR) Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Recycling pathway of L1 Hedgehog 'off' state Cilium Assembly Anchoring of the basal body to the plasma membrane Intraflagellar transport RHO GTPases activate IQGAPs RHO GTPases Activate Formins Neutrophil degranulation COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic COPI-independent Golgi-to-ER retrograde traffic Mitotic Prometaphase The role of GTSE1 in G2/M progression after G2 checkpoint AURKA Activation by TPX2 Carboxyterminal post-translational modifications of tubulin HCMV Early Events Aggrephagy EML4 and NUDC in mitotic spindle formation Sealing of the nuclear envelope (NE) by ESCRT-III Kinesins +38 more

Polycomb repressive complex Formation of Incision Complex in GG-NER

Generic Transcription Pathway

Folate biosynthesis Metabolic pathways Biosynthesis of cofactors GABAergic synapse Molybdenum cofactor biosynthesis +2 more

Growth hormone synthesis, secretion and action

Hedgehog 'off' state Anchoring of the basal body to the plasma membrane