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Jackson-weiss syndrome
Jackson-weiss syndrome
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Pathways column key:
KEGG
Reactome
Disease Term
Disease ID
Gene Symbol
Classification
References
Source
Pathways
Jackson-Weiss syndrome
MONDO_0007400
FGFR1
Causal
25394172
23812909
23154428
12627230
17235395
22319038
25759380
7874170
8528214
9677057
9385368
8644708
10861678
7874169
Open Targets
MAPK signaling pathway
Ras signaling pathway
Rap1 signaling pathway
Calcium signaling pathway
PI3K-Akt signaling pathway
Adherens junction
Signaling pathways regulating pluripotency of stem cells
Thermogenesis
Regulation of actin cytoskeleton
Parathyroid hormone synthesis, secretion and action
Pathways in cancer
Proteoglycans in cancer
Prostate cancer
Melanoma
Breast cancer
Central carbon metabolism in cancer
PI3K Cascade
PIP3 activates AKT signaling
Signaling by FGFR1 amplification mutants
Signaling by activated point mutants of FGFR1
FGFR1b ligand binding and activation
FGFR1c ligand binding and activation
FGFR1c and Klotho ligand binding and activation
Constitutive Signaling by Aberrant PI3K in Cancer
Signal transduction by L1
Phospholipase C-mediated cascade: FGFR1
Downstream signaling of activated FGFR1
SHC-mediated cascade:FGFR1
PI-3K cascade:FGFR1
FRS-mediated FGFR1 signaling
Negative regulation of FGFR1 signaling
Signaling by FGFR1 in disease
RAF/MAP kinase cascade
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
Signaling by plasma membrane FGFR1 fusions
+32 more
FGFR2
Causal
7874170
9385368
27604308
28425981
7719345
7719344
8696350
22387015
7987400
9973282
7655462
9002682
17621648
8528214
15523492
7607643
7581378
22038757
9677057
9152842
19610084
8644708
10861678
11173845
11781872
16844695
10633130
11380921
Open Targets
EGFR tyrosine kinase inhibitor resistance
MAPK signaling pathway
Ras signaling pathway
Rap1 signaling pathway
Calcium signaling pathway
Endocytosis
PI3K-Akt signaling pathway
Signaling pathways regulating pluripotency of stem cells
Regulation of actin cytoskeleton
Pathways in cancer
Prostate cancer
Gastric cancer
Central carbon metabolism in cancer
PI3K Cascade
PIP3 activates AKT signaling
FGFR2c ligand binding and activation
FGFR2b ligand binding and activation
Signaling by FGFR2 amplification mutants
Activated point mutants of FGFR2
Constitutive Signaling by Aberrant PI3K in Cancer
Phospholipase C-mediated cascade; FGFR2
PI-3K cascade:FGFR2
SHC-mediated cascade:FGFR2
FRS-mediated FGFR2 signaling
Negative regulation of FGFR2 signaling
Signaling by FGFR2 in disease
RAF/MAP kinase cascade
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
Signaling by FGFR2 fusions
+26 more
All
2
Causal
2
Unknown
0
Select all
Clear
ClinVar
0
Orphanet
0
Disgenet
0
CTD
0
HPO
0
GWAS catalog
0
GenCC
0
ClinGen
0
Open Targets
2
Related Diseases
Diseases that share the most curated genes with Jackson-weiss syndrome.
5
View disease cluster →
Beare-stevenson cutis gyrata syndrome
2 shared genes
FGFR2, FGFR1
Related via 2 shared genes including FGFR2, FGFR1.
Crouzon syndrome
2 shared genes
FGFR2, FGFR1
Related via 2 shared genes including FGFR2, FGFR1.
Pfeiffer syndrome
2 shared genes
FGFR2, FGFR1
Related via 2 shared genes including FGFR2, FGFR1.
Ankylosis
1 shared gene
FGFR2
Related via 1 shared gene including FGFR2.
Cutis gyrata syndrome
1 shared gene
FGFR2
Related via 1 shared gene including FGFR2.
1
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