Intraductal breast papilloma

EGFR tyrosine kinase inhibitor resistance Endocrine resistance Platinum drug resistance MAPK signaling pathway ErbB signaling pathway Ras signaling pathway Rap1 signaling pathway cGMP-PKG signaling pathway cAMP signaling pathway Chemokine signaling pathway HIF-1 signaling pathway FoxO signaling pathway Sphingolipid signaling pathway Phospholipase D signaling pathway Autophagy - animal mTOR signaling pathway PI3K-Akt signaling pathway AMPK signaling pathway Apoptosis Longevity regulating pathway Longevity regulating pathway - multiple species Cellular senescence Adrenergic signaling in cardiomyocytes VEGF signaling pathway Apelin signaling pathway Osteoclast differentiation Focal adhesion Signaling pathways regulating pluripotency of stem cells Platelet activation Neutrophil extracellular trap formation Toll-like receptor signaling pathway C-type lectin receptor signaling pathway JAK-STAT signaling pathway T cell receptor signaling pathway B cell receptor signaling pathway Fc epsilon RI signaling pathway Fc gamma R-mediated phagocytosis TNF signaling pathway Neurotrophin signaling pathway Cholinergic synapse Dopaminergic synapse Regulation of actin cytoskeleton Insulin signaling pathway Progesterone-mediated oocyte maturation Estrogen signaling pathway Prolactin signaling pathway Thyroid hormone signaling pathway Adipocytokine signaling pathway Glucagon signaling pathway Regulation of lipolysis in adipocytes Relaxin signaling pathway GnRH secretion Insulin resistance Non-alcoholic fatty liver disease AGE-RAGE signaling pathway in diabetic complications Growth hormone synthesis, secretion and action Alcoholic liver disease Carbohydrate digestion and absorption Alzheimer disease Spinocerebellar ataxia Shigellosis Salmonella infection Yersinia infection Chagas disease Toxoplasmosis Tuberculosis Hepatitis C Hepatitis B Measles Human cytomegalovirus infection Influenza A Human papillomavirus infection Human T-cell leukemia virus 1 infection Kaposi sarcoma-associated herpesvirus infection Herpes simplex virus 1 infection Epstein-Barr virus infection Human immunodeficiency virus 1 infection Pathways in cancer Proteoglycans in cancer Chemical carcinogenesis - receptor activation Chemical carcinogenesis - reactive oxygen species Colorectal cancer Renal cell carcinoma Pancreatic cancer Endometrial cancer Glioma Prostate cancer Melanoma Chronic myeloid leukemia Acute myeloid leukemia Small cell lung cancer Non-small cell lung cancer Breast cancer Hepatocellular carcinoma Gastric cancer Central carbon metabolism in cancer Choline metabolism in cancer PD-L1 expression and PD-1 checkpoint pathway in cancer Diabetic cardiomyopathy Lipid and atherosclerosis Fluid shear stress and atherosclerosis PIP3 activates AKT signaling Downregulation of ERBB2:ERBB3 signaling Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation mTOR signalling AKT phosphorylates targets in the cytosol AKT phosphorylates targets in the nucleus Negative regulation of the PI3K/AKT network eNOS activation AKT-mediated inactivation of FOXO1A Integrin signaling Deactivation of the beta-catenin transactivating complex CD28 dependent PI3K/Akt signaling CTLA4 inhibitory signaling G beta:gamma signalling through PI3Kgamma Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA KSRP (KHSRP) binds and destabilizes mRNA VEGFR2 mediated vascular permeability TP53 Regulates Metabolic Genes Constitutive Signaling by AKT1 E17K in Cancer Interleukin-4 and Interleukin-13 signaling Regulation of TP53 Degradation Regulation of TP53 Activity through Acetylation Regulation of TP53 Activity through Association with Co-factors PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling Cyclin E associated events during G1/S transition Cyclin A:Cdk2-associated events at S phase entry PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 RAB GEFs exchange GTP for GDP on RABs Regulation of PTEN stability and activity Extra-nuclear estrogen signaling Negative regulation of NOTCH4 signaling Regulation of localization of FOXO transcription factors Estrogen-dependent nuclear events downstream of ESR-membrane signaling +131 more

Endocrine resistance Rap1 signaling pathway Calcium signaling pathway cAMP signaling pathway Phospholipase D signaling pathway Hormone signaling Adrenergic signaling in cardiomyocytes Vascular smooth muscle contraction Gap junction Platelet activation Circadian entrainment Thermogenesis Glutamatergic synapse Serotonergic synapse Dopaminergic synapse Long-term depression Inflammatory mediator regulation of TRP channels Insulin secretion GnRH signaling pathway Ovarian steroidogenesis Estrogen signaling pathway Melanogenesis Thyroid hormone synthesis Oxytocin signaling pathway Glucagon signaling pathway Regulation of lipolysis in adipocytes Renin secretion Aldosterone synthesis and secretion Relaxin signaling pathway Cortisol synthesis and secretion Parathyroid hormone synthesis, secretion and action Cushing syndrome Growth hormone synthesis, secretion and action Endocrine and other factor-regulated calcium reabsorption Vasopressin-regulated water reabsorption Salivary secretion Gastric acid secretion Pancreatic secretion Bile secretion Parkinson disease Cocaine addiction Amphetamine addiction Morphine addiction Alcoholism Vibrio cholerae infection Chagas disease Amoebiasis Human cytomegalovirus infection Human papillomavirus infection Pathways in cancer Chemical carcinogenesis - receptor activation Dilated cardiomyopathy Glucagon signaling in metabolic regulation PKA activation in glucagon signalling Glucagon-like Peptide-1 (GLP1) regulates insulin secretion Prostacyclin signalling through prostacyclin receptor G alpha (s) signalling events Glucagon-type ligand receptors Vasopressin regulates renal water homeostasis via Aquaporins Hedgehog 'off' state ADORA2B mediated anti-inflammatory cytokines production +58 more

EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway ErbB signaling pathway Ras signaling pathway Rap1 signaling pathway Chemokine signaling pathway FoxO signaling pathway Sphingolipid signaling pathway Phospholipase D signaling pathway Mitophagy - animal Autophagy - animal Endocytosis mTOR signaling pathway PI3K-Akt signaling pathway Apoptosis Longevity regulating pathway Longevity regulating pathway - multiple species Cellular senescence Axon guidance VEGF signaling pathway Apelin signaling pathway Focal adhesion Gap junction Signaling pathways regulating pluripotency of stem cells C-type lectin receptor signaling pathway JAK-STAT signaling pathway Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway Fc epsilon RI signaling pathway Thermogenesis Long-term potentiation Neurotrophin signaling pathway Cholinergic synapse Serotonergic synapse Long-term depression Regulation of actin cytoskeleton Insulin signaling pathway GnRH signaling pathway Estrogen signaling pathway Melanogenesis Prolactin signaling pathway Thyroid hormone signaling pathway Oxytocin signaling pathway Relaxin signaling pathway GnRH secretion AGE-RAGE signaling pathway in diabetic complications Growth hormone synthesis, secretion and action Alzheimer disease Pathways of neurodegeneration - multiple diseases Alcoholism Salmonella infection Hepatitis C Hepatitis B Human cytomegalovirus infection Human papillomavirus infection Human T-cell leukemia virus 1 infection Kaposi sarcoma-associated herpesvirus infection Human immunodeficiency virus 1 infection Pathways in cancer Viral carcinogenesis Proteoglycans in cancer MicroRNAs in cancer Chemical carcinogenesis - receptor activation Chemical carcinogenesis - reactive oxygen species Colorectal cancer Renal cell carcinoma Endometrial cancer Glioma Prostate cancer Thyroid cancer Melanoma Bladder cancer Chronic myeloid leukemia Acute myeloid leukemia Non-small cell lung cancer Breast cancer Hepatocellular carcinoma Gastric cancer Central carbon metabolism in cancer Choline metabolism in cancer PD-L1 expression and PD-1 checkpoint pathway in cancer Lipid and atherosclerosis Activation of RAS in B cells Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants SHC1 events in ERBB4 signaling Signaling by SCF-KIT p38MAPK events GRB2 events in EGFR signaling SHC1 events in EGFR signaling Downstream signal transduction GRB2 events in ERBB2 signaling Tie2 Signaling EGFR Transactivation by Gastrin DAP12 signaling FCERI mediated MAPK activation NCAM signaling for neurite out-growth EPHB-mediated forward signaling VEGFR2 mediated cell proliferation CD209 (DC-SIGN) signaling Constitutive Signaling by EGFRvIII SHC-mediated cascade:FGFR1 FRS-mediated FGFR1 signaling SHC-mediated cascade:FGFR2 FRS-mediated FGFR2 signaling SHC-mediated cascade:FGFR3 FRS-mediated FGFR3 signaling FRS-mediated FGFR4 signaling SHC-mediated cascade:FGFR4 Signaling by FGFR2 in disease Signaling by FGFR4 in disease Signaling by FGFR1 in disease Regulation of RAS by GAPs RAF activation RAF/MAP kinase cascade MAP2K and MAPK activation Negative regulation of MAPK pathway Signaling by moderate kinase activity BRAF mutants Signaling by high-kinase activity BRAF mutants Signaling by BRAF and RAF fusions RAS signaling downstream of NF1 loss-of-function variants Paradoxical activation of RAF signaling by kinase inactive BRAF PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases MET activates RAS signaling Signaling by FGFR3 fusions in cancer Signaling by FGFR3 point mutants in cancer FLT3 Signaling Constitutive Signaling by Overexpressed ERBB2 Estrogen-stimulated signaling through PRKCZ RAS GTPase cycle mutants Signaling downstream of RAS mutants Signaling by ERBB2 KD Mutants Signaling by ERBB2 ECD mutants Signaling by ERBB2 TMD/JMD mutants Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants Signaling by PDGFRA extracellular domain mutants +134 more

Inositol phosphate metabolism Metabolic pathways EGFR tyrosine kinase inhibitor resistance Endocrine resistance Platinum drug resistance ErbB signaling pathway Ras signaling pathway Rap1 signaling pathway cAMP signaling pathway Chemokine signaling pathway HIF-1 signaling pathway FoxO signaling pathway Phosphatidylinositol signaling system Sphingolipid signaling pathway Phospholipase D signaling pathway Hormone signaling Autophagy - animal mTOR signaling pathway PI3K-Akt signaling pathway AMPK signaling pathway Apoptosis Longevity regulating pathway Longevity regulating pathway - multiple species Cellular senescence Axon guidance VEGF signaling pathway Osteoclast differentiation Focal adhesion Signaling pathways regulating pluripotency of stem cells Platelet activation Neutrophil extracellular trap formation Toll-like receptor signaling pathway C-type lectin receptor signaling pathway JAK-STAT signaling pathway Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway Fc epsilon RI signaling pathway Fc gamma R-mediated phagocytosis TNF signaling pathway Leukocyte transendothelial migration Neurotrophin signaling pathway Cholinergic synapse Inflammatory mediator regulation of TRP channels Regulation of actin cytoskeleton Insulin signaling pathway Progesterone-mediated oocyte maturation Estrogen signaling pathway Prolactin signaling pathway Thyroid hormone signaling pathway Regulation of lipolysis in adipocytes Relaxin signaling pathway GnRH secretion Type II diabetes mellitus Insulin resistance Non-alcoholic fatty liver disease AGE-RAGE signaling pathway in diabetic complications Growth hormone synthesis, secretion and action Aldosterone-regulated sodium reabsorption Carbohydrate digestion and absorption Alzheimer disease Spinocerebellar ataxia Prion disease Bacterial invasion of epithelial cells Shigellosis Salmonella infection Yersinia infection Chagas disease Amoebiasis Hepatitis C Hepatitis B Measles Human cytomegalovirus infection Influenza A Human papillomavirus infection Human T-cell leukemia virus 1 infection Kaposi sarcoma-associated herpesvirus infection Herpes simplex virus 1 infection Epstein-Barr virus infection Human immunodeficiency virus 1 infection Coronavirus disease - COVID-19 Pathways in cancer Viral carcinogenesis Proteoglycans in cancer MicroRNAs in cancer Chemical carcinogenesis - receptor activation Chemical carcinogenesis - reactive oxygen species Colorectal cancer Renal cell carcinoma Pancreatic cancer Endometrial cancer Glioma Prostate cancer Melanoma Chronic myeloid leukemia Acute myeloid leukemia Small cell lung cancer Non-small cell lung cancer Breast cancer Hepatocellular carcinoma Gastric cancer Central carbon metabolism in cancer Choline metabolism in cancer PD-L1 expression and PD-1 checkpoint pathway in cancer Diabetic cardiomyopathy Lipid and atherosclerosis Fluid shear stress and atherosclerosis PI3K Cascade IRS-mediated signalling GPVI-mediated activation cascade Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants PI3K events in ERBB4 signaling PIP3 activates AKT signaling Signaling by SCF-KIT Synthesis of PIPs at the plasma membrane GAB1 signalosome Signaling by cytosolic FGFR1 fusion mutants Downstream signal transduction PI3K events in ERBB2 signaling PI3K/AKT activation Downstream TCR signaling Role of phospholipids in phagocytosis Tie2 Signaling Constitutive Signaling by Aberrant PI3K in Cancer DAP12 signaling Role of LAT2/NTAL/LAB on calcium mobilization Costimulation by the CD28 family CD28 dependent PI3K/Akt signaling G alpha (q) signalling events VEGFA-VEGFR2 Pathway Interleukin-3, Interleukin-5 and GM-CSF signaling Constitutive Signaling by EGFRvIII PI-3K cascade:FGFR1 PI-3K cascade:FGFR2 PI-3K cascade:FGFR3 PI-3K cascade:FGFR4 Signaling by FGFR2 in disease Signaling by FGFR4 in disease Signaling by FGFR1 in disease PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling MET activates PI3K/AKT signaling Signaling by FGFR3 fusions in cancer Signaling by FGFR3 point mutants in cancer RET signaling Extra-nuclear estrogen signaling Erythropoietin activates Phosphoinositide-3-kinase (PI3K) Interleukin receptor SHC signaling Regulation of signaling by CBL Signaling by ERBB2 KD Mutants Signaling by ERBB2 ECD mutants Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants Signaling by PDGFRA extracellular domain mutants +149 more