Hodgkin lymphoma

Phagosome Cell adhesion molecules Antigen processing and presentation Hematopoietic cell lineage Th1 and Th2 cell differentiation Th17 cell differentiation Intestinal immune network for IgA production Type I diabetes mellitus Leishmaniasis Toxoplasmosis Staphylococcus aureus infection Tuberculosis Influenza A Human T-cell leukemia virus 1 infection Herpes simplex virus 1 infection Epstein-Barr virus infection Asthma Autoimmune thyroid disease Inflammatory bowel disease Systemic lupus erythematosus Rheumatoid arthritis Allograft rejection Graft-versus-host disease Viral myocarditis Downstream TCR signaling Phosphorylation of CD3 and TCR zeta chains Translocation of ZAP-70 to Immunological synapse Generation of second messenger molecules MHC class II antigen presentation PD-1 signaling Interferon gamma signaling +28 more

Cytokine-cytokine receptor interaction JAK-STAT signaling pathway IL-17 signaling pathway Th1 and Th2 cell differentiation Fc epsilon RI signaling pathway Pathways in cancer Asthma Inflammatory bowel disease Interleukin-4 and Interleukin-13 signaling Interleukin-18 signaling +7 more

Phosphatidylinositol signaling system Synthesis of pyrophosphates in the cytosol

Th17 cell differentiation Interleukin-4 and Interleukin-13 signaling Interferon gamma signaling Interferon alpha/beta signaling +1 more

Pertussis Interferon gamma signaling Interferon alpha/beta signaling

Platelet degranulation

Calcium signaling pathway cGMP-PKG signaling pathway Phosphatidylinositol signaling system Oocyte meiosis Apoptosis Cellular senescence Vascular smooth muscle contraction Apelin signaling pathway Osteoclast differentiation Gap junction Platelet activation NOD-like receptor signaling pathway C-type lectin receptor signaling pathway Long-term potentiation Retrograde endocannabinoid signaling Glutamatergic synapse Cholinergic synapse Serotonergic synapse Dopaminergic synapse Long-term depression Inflammatory mediator regulation of TRP channels GnRH signaling pathway Estrogen signaling pathway Thyroid hormone synthesis Oxytocin signaling pathway Glucagon signaling pathway Renin secretion Aldosterone synthesis and secretion Cortisol synthesis and secretion Parathyroid hormone synthesis, secretion and action GnRH secretion Cushing syndrome Growth hormone synthesis, secretion and action Salivary secretion Gastric acid secretion Pancreatic secretion Alzheimer disease Parkinson disease Spinocerebellar ataxia Prion disease Pathways of neurodegeneration - multiple diseases Shigellosis Human cytomegalovirus infection Kaposi sarcoma-associated herpesvirus infection Human immunodeficiency virus 1 infection Proteoglycans in cancer Effects of PIP2 hydrolysis Elevation of cytosolic Ca2+ levels Glucagon-like Peptide-1 (GLP1) regulates insulin secretion Ion homeostasis Antigen activates B Cell Receptor (BCR) leading to generation of second messengers +48 more

Motor proteins COPI-dependent Golgi-to-ER retrograde traffic Kinesins

Malaria Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell

Estrogen signaling pathway Staphylococcus aureus infection Keratinization Formation of the cornified envelope +1 more

LGI-ADAM interactions

Rap1 signaling pathway Phospholipase D signaling pathway Neuroactive ligand-receptor interaction PI3K-Akt signaling pathway Gap junction Regulation of actin cytoskeleton Pathogenic Escherichia coli infection Pathways in cancer G alpha (q) signalling events G alpha (i) signalling events Lysosphingolipid and LPA receptors +8 more

mTOR signaling pathway Wnt signaling pathway Parathyroid hormone synthesis, secretion and action Alzheimer disease Pathways of neurodegeneration - multiple diseases Pathways in cancer Breast cancer Hepatocellular carcinoma Gastric cancer Negative regulation of TCF-dependent signaling by WNT ligand antagonists Disassembly of the destruction complex and recruitment of AXIN to the membrane Regulation of FZD by ubiquitination Misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling RNF mutants show enhanced WNT signaling and proliferation +11 more

Rap1 signaling pathway

EGFR tyrosine kinase inhibitor resistance Endocrine resistance Platinum drug resistance MAPK signaling pathway ErbB signaling pathway Ras signaling pathway Rap1 signaling pathway cGMP-PKG signaling pathway cAMP signaling pathway Chemokine signaling pathway HIF-1 signaling pathway FoxO signaling pathway Sphingolipid signaling pathway Phospholipase D signaling pathway Oocyte meiosis Autophagy - animal Efferocytosis mTOR signaling pathway PI3K-Akt signaling pathway Apoptosis Cellular senescence Adrenergic signaling in cardiomyocytes Vascular smooth muscle contraction TGF-beta signaling pathway Axon guidance VEGF signaling pathway Apelin signaling pathway Osteoclast differentiation Focal adhesion Adherens junction Gap junction Signaling pathways regulating pluripotency of stem cells Platelet activation Neutrophil extracellular trap formation Toll-like receptor signaling pathway NOD-like receptor signaling pathway C-type lectin receptor signaling pathway Natural killer cell mediated cytotoxicity IL-17 signaling pathway Th1 and Th2 cell differentiation Th17 cell differentiation T cell receptor signaling pathway B cell receptor signaling pathway Fc epsilon RI signaling pathway Fc gamma R-mediated phagocytosis TNF signaling pathway Circadian entrainment Long-term potentiation Neurotrophin signaling pathway Retrograde endocannabinoid signaling Glutamatergic synapse Cholinergic synapse Serotonergic synapse Long-term depression Regulation of actin cytoskeleton Insulin signaling pathway GnRH signaling pathway Progesterone-mediated oocyte maturation Estrogen signaling pathway Melanogenesis Prolactin signaling pathway Thyroid hormone signaling pathway Oxytocin signaling pathway Relaxin signaling pathway Parathyroid hormone synthesis, secretion and action GnRH secretion Type II diabetes mellitus AGE-RAGE signaling pathway in diabetic complications Cushing syndrome Growth hormone synthesis, secretion and action Aldosterone-regulated sodium reabsorption Alzheimer disease Prion disease Pathways of neurodegeneration - multiple diseases Alcoholism Pathogenic Escherichia coli infection Shigellosis Salmonella infection Pertussis Yersinia infection Leishmaniasis Chagas disease Toxoplasmosis Tuberculosis Hepatitis C Hepatitis B Human cytomegalovirus infection Influenza A Human papillomavirus infection Human T-cell leukemia virus 1 infection Kaposi sarcoma-associated herpesvirus infection Human immunodeficiency virus 1 infection Coronavirus disease - COVID-19 Pathways in cancer Viral carcinogenesis Proteoglycans in cancer MicroRNAs in cancer Chemical carcinogenesis - receptor activation Chemical carcinogenesis - reactive oxygen species Colorectal cancer Renal cell carcinoma Pancreatic cancer Endometrial cancer Glioma Prostate cancer Thyroid cancer Melanoma Bladder cancer Chronic myeloid leukemia Acute myeloid leukemia Non-small cell lung cancer Breast cancer Hepatocellular carcinoma Gastric cancer Central carbon metabolism in cancer Choline metabolism in cancer PD-L1 expression and PD-1 checkpoint pathway in cancer Lipid and atherosclerosis MAPK3 (ERK1) activation RAF-independent MAPK1/3 activation ISG15 antiviral mechanism Spry regulation of FGF signaling Golgi Cisternae Pericentriolar Stack Reorganization Frs2-mediated activation ERK/MAPK targets ERKs are inactivated Regulation of actin dynamics for phagocytic cup formation Oxidative Stress Induced Senescence Senescence-Associated Secretory Phenotype (SASP) Oncogene Induced Senescence FCERI mediated MAPK activation Regulation of HSF1-mediated heat shock response NCAM signaling for neurite out-growth Signal transduction by L1 Activation of the AP-1 family of transcription factors Thrombin signalling through proteinase activated receptors (PARs) Negative regulation of FGFR1 signaling Negative regulation of FGFR2 signaling Negative regulation of FGFR3 signaling Negative regulation of FGFR4 signaling RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate NADPH Oxidases RAF/MAP kinase cascade MAP2K and MAPK activation Negative feedback regulation of MAPK pathway Negative regulation of MAPK pathway Signaling by moderate kinase activity BRAF mutants Signaling by high-kinase activity BRAF mutants Signaling by BRAF and RAF fusions Paradoxical activation of RAF signaling by kinase inactive BRAF PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling RNA Polymerase I Promoter Opening Signal attenuation Gastrin-CREB signalling pathway via PKC and MAPK ESR-mediated signaling Regulation of PTEN gene transcription Regulation of the apoptosome activity Suppression of apoptosis Signaling downstream of RAS mutants FCGR3A-mediated phagocytosis Growth hormone receptor signaling +158 more

Efferocytosis

Natural killer cell mediated cytotoxicity Kaposi sarcoma-associated herpesvirus infection Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell

Spinocerebellar ataxia Myogenesis

Condensation of Prophase Chromosomes

ErbB signaling pathway Axon guidance T cell receptor signaling pathway Pathogenic Escherichia coli infection Downstream signal transduction Generation of second messenger molecules Regulation of actin dynamics for phagocytic cup formation Nephrin family interactions DCC mediated attractive signaling VEGFA-VEGFR2 Pathway RHO GTPases Activate WASPs and WAVEs FCGR3A-mediated phagocytosis Antigen activates B Cell Receptor (BCR) leading to generation of second messengers +10 more

The retinoid cycle in cones (daylight vision) Retinoid cycle disease events G alpha (i) signalling events Opsins +1 more

mRNA surveillance pathway

EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway Ras signaling pathway Rap1 signaling pathway Calcium signaling pathway Phospholipase D signaling pathway PI3K-Akt signaling pathway Focal adhesion Gap junction Regulation of actin cytoskeleton Prostate cancer Melanoma Choline metabolism in cancer Signaling by PDGF +11 more

Neuroactive ligand-receptor interaction Neutrophil degranulation

PI3K-Akt signaling pathway Negative regulation of the PI3K/AKT network

Glycerophospholipid metabolism Ether lipid metabolism Arachidonic acid metabolism Linoleic acid metabolism alpha-Linolenic acid metabolism Metabolic pathways MAPK signaling pathway Ras signaling pathway Phospholipase D signaling pathway Necroptosis Vascular smooth muscle contraction VEGF signaling pathway Platelet activation Fc epsilon RI signaling pathway Fc gamma R-mediated phagocytosis Glutamatergic synapse Serotonergic synapse Long-term depression Inflammatory mediator regulation of TRP channels GnRH signaling pathway Ovarian steroidogenesis Oxytocin signaling pathway Choline metabolism in cancer phospho-PLA2 pathway Acyl chain remodelling of PC Acyl chain remodeling of CL Acyl chain remodelling of PS Acyl chain remodelling of PE Acyl chain remodelling of PI Acyl chain remodelling of PG Hydrolysis of LPC Synthesis of PA Arachidonic acid metabolism ADP signalling through P2Y purinoceptor 1 Platelet sensitization by LDL COPI-independent Golgi-to-ER retrograde traffic +33 more

Phosphorylation of CD3 and TCR zeta chains Translocation of ZAP-70 to Immunological synapse

EGFR downregulation

Neutrophil degranulation

MAPK signaling pathway Adrenergic signaling in cardiomyocytes TNF signaling pathway Circadian entrainment Neurotrophin signaling pathway Shigellosis Pathways in cancer MicroRNAs in cancer Bladder cancer ERK/MAPK targets CREB phosphorylation NCAM signaling for neurite out-growth CD209 (DC-SIGN) signaling +10 more

Post-translational modification: synthesis of GPI-anchored proteins

Parathyroid hormone synthesis, secretion and action Transcriptional misregulation in cancer Transcriptional regulation by RUNX2 RUNX1 regulates transcription of genes involved in differentiation of myeloid cells Regulation of RUNX2 expression and activity RUNX2 regulates osteoblast differentiation RUNX2 regulates bone development RUNX2 regulates genes involved in cell migration RUNX2 regulates genes involved in differentiation of myeloid cells +6 more

Serine biosynthesis

Complement and coagulation cascades Platelet degranulation Dissolution of Fibrin Clot

Natural killer cell mediated cytotoxicity

Glutamatergic synapse Neurexins and neuroligins

Glycine, serine and threonine metabolism Glyoxylate and dicarboxylate metabolism One carbon pool by folate Metabolic pathways Carbon metabolism Biosynthesis of amino acids Biosynthesis of cofactors Antifolate resistance Folate transport and metabolism Metabolism of folate and pterines Carnitine synthesis +8 more

Synaptic vesicle cycle Cholinergic synapse Acetylcholine Neurotransmitter Release Cycle Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis +2 more

Efferocytosis Scavenging by Class H Receptors

Signaling pathways regulating pluripotency of stem cells Human T-cell leukemia virus 1 infection Transcriptional misregulation in cancer Myogenesis RUNX1 regulates transcription of genes involved in differentiation of HSCs +2 more