Histiocytic and dendritic cell neoplasm | Gene-Disease Associations & Pathways | GeDiPNet

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Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
histiocytic and dendritic cell neoplasm	MONDO_0006247	ALK	Unknown	8558920	Open Targets	Pathways in cancer Non-small cell lung cancer PD-L1 expression and PD-1 checkpoint pathway in cancer
		ARAF	Unknown	25202140	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +41 more
		BCL10	Unknown	28481359	Open Targets	NF-kappa B signaling pathway C-type lectin receptor signaling pathway T cell receptor signaling pathway +8 more
		BCL2	Unknown	28481359	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Platinum drug resistance +46 more
		BRAF	Unknown	24638167 24720374 24567436 31172191 25209580 25202140	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +52 more
		CD209	Unknown	31172191	Open Targets	Virion - Human immunodeficiency virus Virion - Flavivirus and Alphavirus Virion - Ebolavirus, Lyssavirus and Morbillivirus +7 more
		CDKN1B	Unknown	28481359	Open Targets	Endocrine resistance ErbB signaling pathway HIF-1 signaling pathway +28 more
		ERBB3	Unknown	25202140	Open Targets	EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway ErbB signaling pathway +19 more
		FAM47C	Unknown	31172191	Open Targets	—
		KIT	Unknown	28481359	Open Targets	MAPK signaling pathway Ras signaling pathway Rap1 signaling pathway +15 more
		KRAS	Unknown	31172191	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +134 more
		MAP2K1	Unknown	29768143 28481359	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +99 more
		MUC4	Unknown	31172191	Open Targets	Defective GALNT3 causes familial hyperphosphatemic tumoral calcinosis (HFTC) Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS) Defective GALNT12 causes colorectal cancer 1 (CRCS1) +3 more
		NPM1	Unknown	8558920	Open Targets	Nuclear import of Rev protein SUMOylation of transcription cofactors Deposition of new CENPA-containing nucleosomes at the centromere +2 more
		PTEN	Unknown	26110571	Open Targets	Inositol phosphate metabolism Metabolic pathways EGFR tyrosine kinase inhibitor resistance +37 more
		TCF7L2	Unknown	31172191	Open Targets	Wnt signaling pathway Hippo signaling pathway Adherens junction +26 more
		TP53	Unknown	31172191	Open Targets	Endocrine resistance Platinum drug resistance MAPK signaling pathway +85 more