Gastric cancer | Gene-Disease Associations & Pathways | GeDiPNet

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Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
GASTRIC CANCER	613659 MONDO:0001056 MONDO_0001056	APC	Causal	15457249 3034404 25820570 7773929 17344846 15273732 11973654 15824733 14534542 10395927 9679752	ClinVar, HPO	Wnt signaling pathway Hippo signaling pathway Signaling pathways regulating pluripotency of stem cells +28 more
		BRCA2	Causal	27197191 34290314	GWAS catalog	Homologous recombination Fanconi anemia pathway Pathways in cancer +7 more
		CASP10	Causal	3034404 7773929 17344846 15824733 14534542 15457249 25820570 10395927 11973654 9679752 15273732	ClinVar, HPO	Apoptosis RIG-I-like receptor signaling pathway TNF signaling pathway +6 more
		ERBB2	Causal	15457249 15824733 14534542 7773929 17344846 15273732 25820570 11973654 10395927 3034404 9679752	ClinVar, HPO	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Platinum drug resistance +48 more
		FANCA	Causal	33893285 34290314	GWAS catalog	Fanconi anemia pathway Fanconi Anemia Pathway
		FGFR2	Causal	34290314 37340002	ClinVar, GWAS catalog, HPO	EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway Ras signaling pathway +26 more
		HOXB13	Causal	34290314	GWAS catalog	—
		IRF1	Causal	11973654 15273732 25820570 7773929 17344846 14534542 15457249 9679752 3034404 10395927 15824733	ClinVar, HPO	C-type lectin receptor signaling pathway TNF signaling pathway Prolactin signaling pathway +5 more
		KLF6	Causal	3034404 7773929 10395927 15824733 11973654 15273732 25820570 17344846 14534542 15457249 9679752	ClinVar, HPO	—
		KRAS	Causal	14534542 3034404 17344846 7773929 25820570 15273732 15457249 9679752 11973654 15824733 10395927	ClinVar, HPO	EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +134 more
		MUTYH	Causal	15273732 9679752 3034404 10395927 11973654 15457249 15824733 25820570 7773929 17344846 14534542	ClinVar, HPO	Base excision repair Recognition and association of DNA glycosylase with site containing an affected purine Cleavage of the damaged purine +2 more
		PALB2	Causal	34290314	GWAS catalog	Homologous recombination Fanconi anemia pathway HDR through Homologous Recombination (HRR) +3 more
		PIK3CA	Causal	—	ClinVar, HPO	Inositol phosphate metabolism Metabolic pathways EGFR tyrosine kinase inhibitor resistance +149 more
		TP53	Causal	28346444	GWAS catalog	Endocrine resistance Platinum drug resistance MAPK signaling pathway +85 more