Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
extranodal nasal NK/T cell lymphoma	MONDO_0019472	PDGFRB	Unknown	26192917	Open Targets	EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway Ras signaling pathway +22 more
		PIK3CA	Unknown	29674644	Open Targets	Inositol phosphate metabolism Metabolic pathways EGFR tyrosine kinase inhibitor resistance +149 more
		PMS2	Unknown	26192917	Open Targets	Mismatch repair Fanconi anemia pathway Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) +3 more
		PPP2R1A	Unknown	26773734	Open Targets	mRNA surveillance pathway Sphingolipid signaling pathway Cell cycle +52 more
		PRDM1	Unknown	26192917 21690554	Open Targets	Regulation of TP53 Expression
		PRKD1	Unknown	26192917	Open Targets	Rap1 signaling pathway Aldosterone synthesis and secretion Chemical carcinogenesis - reactive oxygen species +1 more
		PTPRC	Unknown	26192917 22705984	Open Targets	Cell adhesion molecules T cell receptor signaling pathway Fc gamma R-mediated phagocytosis +5 more
		PTPRD	Unknown	24413734	Open Targets	Cell adhesion molecules Receptor-type tyrosine-protein phosphatases Synaptic adhesion-like molecules
		PTPRT	Unknown	26192917 22705984	Open Targets	—
		RGS7	Unknown	26192917	Open Targets	G alpha (i) signalling events Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
		RHOA	Unknown	24584070	Open Targets	Ras signaling pathway Rap1 signaling pathway cGMP-PKG signaling pathway +64 more
		ROBO2	Unknown	26192917	Open Targets	Axon guidance Signaling by ROBO receptors Regulation of commissural axon pathfinding by SLIT and ROBO
		RPN1	Unknown	22705984	Open Targets	N-Glycan biosynthesis Various types of N-glycan biosynthesis Metabolic pathways +2 more
		SETD2	Unknown	26773734 24413734	Open Targets	Lysine degradation Metabolic pathways PKMTs methylate histone lysines
		SF3B1	Unknown	29674644	Open Targets	Spliceosome B-WICH complex positively regulates rRNA expression mRNA Splicing - Major Pathway +1 more
		SHTN1	Unknown	26192917	Open Targets	—
		SMARCB1	Unknown	26773734	Open Targets	ATP-dependent chromatin remodeling Viral life cycle - HIV-1 Thermogenesis +3 more
		SMO	Unknown	26773734	Open Targets	Hedgehog signaling pathway Axon guidance Pathways in cancer +6 more
		SPEN	Unknown	26192917	Open Targets	Notch signaling pathway
		SRGAP3	Unknown	26192917	Open Targets	Axon guidance Rho GTPase cycle
		STAT3	Unknown	31394087 26773734 23872306 25586472 27203213 29674644 26192917	Open Targets	EGFR tyrosine kinase inhibitor resistance Chemokine signaling pathway HIF-1 signaling pathway +53 more
		STAT5B	Unknown	25586472 29674644 26192917	Open Targets	ErbB signaling pathway Chemokine signaling pathway Hormone signaling +28 more
		TBX3	Unknown	26192917	Open Targets	Signaling pathways regulating pluripotency of stem cells
		TCF3	Unknown	27203213	Open Targets	Signaling pathways regulating pluripotency of stem cells Human T-cell leukemia virus 1 infection Transcriptional misregulation in cancer +2 more
		TET2	Unknown	26773734 31394087 31123138	Open Targets	—
		TP53	Unknown	11230707 22705984 26773734 10780666 27203213 12824925 11896204 16596195 26192917 11733360 14745729 15643509	Open Targets	Endocrine resistance Platinum drug resistance MAPK signaling pathway +85 more
		TRRAP	Unknown	26192917	Open Targets	ATP-dependent chromatin remodeling Human T-cell leukemia virus 1 infection Formation of the beta-catenin:TCF transactivating complex +1 more
		TSC2	Unknown	26773734	Open Targets	Phospholipase D signaling pathway p53 signaling pathway Autophagy - animal +19 more
		XPO1	Unknown	26773734	Open Targets	Ribosome biogenesis in eukaryotes Nucleocytoplasmic transport Viral life cycle - HIV-1 +15 more
		ZFHX3	Unknown	26192917	Open Targets	Signaling pathways regulating pluripotency of stem cells RUNX3 regulates CDKN1A transcription
		ZMYM2	Unknown	26192917	Open Targets	Signaling by cytosolic FGFR1 fusion mutants Signaling by FGFR1 in disease
		ZNF479	Unknown	26192917	Open Targets	Generic Transcription Pathway

«‹1 23›»

Extranodal nasal nk/t cell lymphoma

Bookmark This Disease