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Eosinophilic leukemia
Eosinophilic leukemia
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Pathways column key:
KEGG
Reactome
Disease Term
Disease ID
Gene Symbol
Classification
References
Source
Pathways
CHRONIC EOSINOPHILIC LEUKEMIA
168940
FIP1L1
Unknown
16502585
17988989
22523564
24764730
Orphanet
mRNA surveillance pathway
Transport of Mature mRNA Derived from an Intronless Transcript
mRNA Splicing - Major Pathway
mRNA 3'-end processing
RNA Polymerase II Transcription Termination
Processing of Intronless Pre-mRNAs
Signaling by cytosolic PDGFRA and PDGFRB fusion proteins
+4 more
PDGFRA
Unknown
16502585
17988989
22523564
24764730
Orphanet
EGFR tyrosine kinase inhibitor resistance
MAPK signaling pathway
Ras signaling pathway
Rap1 signaling pathway
Calcium signaling pathway
Phospholipase D signaling pathway
Endocytosis
PI3K-Akt signaling pathway
Focal adhesion
Gap junction
JAK-STAT signaling pathway
Regulation of actin cytoskeleton
Human cytomegalovirus infection
Pathways in cancer
MicroRNAs in cancer
Glioma
Prostate cancer
Melanoma
Central carbon metabolism in cancer
Choline metabolism in cancer
PIP3 activates AKT signaling
Downstream signal transduction
Signaling by PDGF
Constitutive Signaling by Aberrant PI3K in Cancer
RAF/MAP kinase cascade
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants
Signaling by PDGFRA extracellular domain mutants
Imatinib-resistant PDGFR mutants
Sunitinib-resistant PDGFR mutants
Regorafenib-resistant PDGFR mutants
Sorafenib-resistant PDGFR mutants
PDGFR mutants bind TKIs
+30 more
All
2
Causal
0
Unknown
2
Select all
Clear
ClinVar
0
Orphanet
2
Disgenet
0
CTD
0
HPO
0
GWAS catalog
0
GenCC
0
ClinGen
0
Related Diseases
Diseases that share the most curated genes with Eosinophilic leukemia.
5
View disease cluster →
Hypereosinophilic syndrome
2 shared genes
PDGFRA, FIP1L1
Related via 2 shared genes including PDGFRA, FIP1L1.
Congenital respiratory system anomaly
1 shared gene
PDGFRA
Related via 1 shared gene including PDGFRA.
Chondrosarcoma
1 shared gene
PDGFRA
Related via 1 shared gene including PDGFRA.
Thyroid gland neoplasms
1 shared gene
PDGFRA
Related via 1 shared gene including PDGFRA.
Cleft lip and palate
1 shared gene
PDGFRA
Related via 1 shared gene including PDGFRA.
1
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