Subtype of: Endometrial cancer

Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
endometrial endometrioid adenocarcinoma	MONDO_0006192	BRAF	Unknown	15118616 18084252 23370429 23199529 22653804 15723290 29876005 16619251 28481359	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +52 more
		BRCA1	Unknown	33016334 29420467 28481359 27159395	Open Targets	Platinum drug resistance Homologous recombination Fanconi anemia pathway +19 more
		BRCA2	Unknown	37328769 33016334 28481359 27159395	Open Targets	Homologous recombination Fanconi anemia pathway Pathways in cancer +7 more
		BRD3	Unknown	33016334 29162652	Open Targets	—
		BRD4	Unknown	28481359	Open Targets	—
		BRIP1	Unknown	33016334 28481359	Open Targets	Homologous recombination Fanconi anemia pathway HDR through Single Strand Annealing (SSA) +8 more
		BTG1	Unknown	33016334	Open Targets	RNA degradation FOXO-mediated transcription of cell cycle genes
		BTK	Unknown	33016334 28481359 27159395	Open Targets	NF-kappa B signaling pathway Osteoclast differentiation Platelet activation +17 more
		CACNA1D	Unknown	33016334	Open Targets	MAPK signaling pathway Calcium signaling pathway cGMP-PKG signaling pathway +35 more
		CALR	Unknown	36142641 28481359	Open Targets	Protein processing in endoplasmic reticulum Phagosome Efferocytosis +14 more
		CAMTA1	Unknown	33016334	Open Targets	—
		CARD11	Unknown	33016334 28481359	Open Targets	NF-kappa B signaling pathway T cell receptor signaling pathway B cell receptor signaling pathway +4 more
		CASP8	Unknown	28481359	Open Targets	Platinum drug resistance p53 signaling pathway Apoptosis +53 more
		CASP9	Unknown	33016334	Open Targets	Platinum drug resistance p53 signaling pathway PI3K-Akt signaling pathway +39 more
		CBFB	Unknown	28481359	Open Targets	RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs) Transcriptional regulation by RUNX2 RUNX1 regulates estrogen receptor mediated transcription +20 more
		CBL	Unknown	37328769 28481359 27159395	Open Targets	ErbB signaling pathway Ubiquitin mediated proteolysis Endocytosis +22 more
		CCNC	Unknown	33016334	Open Targets	PPARA activates gene expression Generic Transcription Pathway SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription +3 more
		CCND1	Unknown	28481359	Open Targets	Endocrine resistance FoxO signaling pathway Cell cycle +58 more
		CCND3	Unknown	28481359	Open Targets	Cell cycle p53 signaling pathway PI3K-Akt signaling pathway +17 more
		CD274	Unknown	28481359	Open Targets	Cell adhesion molecules PD-L1 expression and PD-1 checkpoint pathway in cancer PD-1 signaling
		CD79A	Unknown	28481359 27159395	Open Targets	B cell receptor signaling pathway Primary immunodeficiency CD22 mediated BCR regulation +1 more
		CD79B	Unknown	28481359	Open Targets	B cell receptor signaling pathway CD22 mediated BCR regulation Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
		CDC73	Unknown	28481359 27159395	Open Targets	Formation of RNA Pol II elongation complex Formation of the beta-catenin:TCF transactivating complex Hedgehog 'on' state +3 more
		CDH1	Unknown	29876005 33016334 28481359	Open Targets	Rap1 signaling pathway Apelin signaling pathway Hippo signaling pathway +15 more
		CDH10	Unknown	33016334	Open Targets	Adherens junctions interactions
		CDK12	Unknown	37328769 28481359 27159395	Open Targets	TP53 Regulates Transcription of DNA Repair Genes
		CDK4	Unknown	28481359	Open Targets	Endocrine resistance Cell cycle p53 signaling pathway +40 more
		CDKN1A	Unknown	28481359	Open Targets	Endocrine resistance Platinum drug resistance ErbB signaling pathway +56 more
		CDKN1B	Unknown	28481359	Open Targets	Endocrine resistance ErbB signaling pathway HIF-1 signaling pathway +28 more
		CDKN2A	Unknown	35953603 10408854 12920579 37298034 32909971 15723290 28481359	Open Targets	Endocrine resistance Platinum drug resistance Cell cycle +33 more
		CEP89	Unknown	33016334	Open Targets	Anchoring of the basal body to the plasma membrane
		CHD4	Unknown	30710169 23104009 33016334 27159395	Open Targets	ATP-dependent chromatin remodeling Human papillomavirus infection Viral carcinogenesis +5 more
		CHEK2	Unknown	28481359 32909971	Open Targets	Cell cycle p53 signaling pathway Cellular senescence +9 more
		CIC	Unknown	33016334 28481359	Open Targets	Spinocerebellar ataxia
		CIITA	Unknown	33016334	Open Targets	Antigen processing and presentation Toxoplasmosis Tuberculosis +3 more
		CLP1	Unknown	33016334	Open Targets	mRNA surveillance pathway tRNA processing in the nucleus mRNA Splicing - Major Pathway +3 more
		CLTCL1	Unknown	33016334	Open Targets	Lysosome Endocytosis Synaptic vesicle cycle +8 more
		CNOT3	Unknown	33016334	Open Targets	RNA degradation Deadenylation of mRNA TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain
		COL1A1	Unknown	33016334	Open Targets	PI3K-Akt signaling pathway Focal adhesion ECM-receptor interaction +26 more
		COL2A1	Unknown	33016334	Open Targets	PI3K-Akt signaling pathway Focal adhesion ECM-receptor interaction +14 more
		CREBBP	Unknown	30886885 32909971 33016334 28481359 35953603	Open Targets	Polycomb repressive complex Viral life cycle - HIV-1 cAMP signaling pathway +52 more
		CRLF2	Unknown	33016334 28481359	Open Targets	Cytokine-cytokine receptor interaction JAK-STAT signaling pathway Interleukin-7 signaling
		CRNKL1	Unknown	33016334	Open Targets	Spliceosome mRNA Splicing - Major Pathway
		CRTC1	Unknown	33016334	Open Targets	Human T-cell leukemia virus 1 infection Transcriptional activation of mitochondrial biogenesis Circadian Clock
		CRTC3	Unknown	33016334	Open Targets	Human T-cell leukemia virus 1 infection Transcriptional activation of mitochondrial biogenesis Circadian Clock
		CSF1R	Unknown	28481359 27159395	Open Targets	MAPK signaling pathway Ras signaling pathway Rap1 signaling pathway +10 more
		CSF3R	Unknown	28481359	Open Targets	Cytokine-cytokine receptor interaction PI3K-Akt signaling pathway JAK-STAT signaling pathway +3 more
		CSMD3	Unknown	33016334	Open Targets	—
		CTCF	Unknown	30886832 30710169 28319062 26330387 32909971 27566247 33016334 28481359 24130125	Open Targets	—
		CTNNA1	Unknown	37328769	Open Targets	Hippo signaling pathway Adherens junction Leukocyte transendothelial migration +9 more

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Endometrial endometrioid adenocarcinoma

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