Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
eccrine porocarcinoma	MONDO_0006189	CASP8	Unknown	34045664	Open Targets	Platinum drug resistance p53 signaling pathway Apoptosis +53 more
		CASP9	Unknown	34045664	Open Targets	Platinum drug resistance p53 signaling pathway PI3K-Akt signaling pathway +39 more
		CBFA2T3	Unknown	34045664	Open Targets	—
		CBLB	Unknown	34045664	Open Targets	ErbB signaling pathway Ubiquitin mediated proteolysis Endocytosis +5 more
		CBLC	Unknown	34185311	Open Targets	Ubiquitin mediated proteolysis Endocytosis
		CCND1	Unknown	34045664	Open Targets	Endocrine resistance FoxO signaling pathway Cell cycle +58 more
		CCNE1	Unknown	34045664	Open Targets	Cell cycle Oocyte meiosis p53 signaling pathway +24 more
		CCR4	Unknown	34045664	Open Targets	Cytokine-cytokine receptor interaction Viral protein interaction with cytokine and cytokine receptor Chemokine signaling pathway +4 more
		CD28	Unknown	34045664	Open Targets	Cell adhesion molecules T cell receptor signaling pathway Intestinal immune network for IgA production +16 more
		CDH10	Unknown	34185311 34045664	Open Targets	Adherens junctions interactions
		CDH11	Unknown	34045664	Open Targets	Adherens junctions interactions
		CDH17	Unknown	34045664	Open Targets	Gastric cancer Adherens junctions interactions
		CDK12	Unknown	34045664	Open Targets	TP53 Regulates Transcription of DNA Repair Genes
		CDK6	Unknown	34045664	Open Targets	Cell cycle p53 signaling pathway PI3K-Akt signaling pathway +27 more
		CDKN1B	Unknown	34045664	Open Targets	Endocrine resistance ErbB signaling pathway HIF-1 signaling pathway +28 more
		CDKN2A	Unknown	31145701 29872726 34045664 31038235 29269125 27067779	Open Targets	Endocrine resistance Platinum drug resistance Cell cycle +33 more
		CEBPA	Unknown	34045664	Open Targets	Non-alcoholic fatty liver disease Pathways in cancer Transcriptional misregulation in cancer +3 more
		CEP89	Unknown	34045664	Open Targets	Anchoring of the basal body to the plasma membrane
		CHD2	Unknown	34045664	Open Targets	—
		CIC	Unknown	34045664	Open Targets	Spinocerebellar ataxia
		CIITA	Unknown	34045664	Open Targets	Antigen processing and presentation Toxoplasmosis Tuberculosis +3 more
		CLP1	Unknown	34045664	Open Targets	mRNA surveillance pathway tRNA processing in the nucleus mRNA Splicing - Major Pathway +3 more
		CLTC	Unknown	34185311	Open Targets	Lysosome Endocytosis Synaptic vesicle cycle +18 more
		CLTCL1	Unknown	34045664	Open Targets	Lysosome Endocytosis Synaptic vesicle cycle +8 more
		CNBD1	Unknown	34185311 34045664	Open Targets	—
		CNTNAP2	Unknown	34185311 34045664	Open Targets	Cell adhesion molecules
		COL1A1	Unknown	34045664	Open Targets	PI3K-Akt signaling pathway Focal adhesion ECM-receptor interaction +26 more
		COL2A1	Unknown	34045664	Open Targets	PI3K-Akt signaling pathway Focal adhesion ECM-receptor interaction +14 more
		COL3A1	Unknown	34045664	Open Targets	Platelet activation Cytoskeleton in muscle cells Relaxin signaling pathway +16 more
		COX6C	Unknown	34045664	Open Targets	Oxidative phosphorylation Metabolic pathways Cardiac muscle contraction +12 more
		CREB3L1	Unknown	34045664	Open Targets	cGMP-PKG signaling pathway cAMP signaling pathway PI3K-Akt signaling pathway +32 more
		CREBBP	Unknown	34185311 34045664	Open Targets	Polycomb repressive complex Viral life cycle - HIV-1 cAMP signaling pathway +52 more
		CRNKL1	Unknown	34045664	Open Targets	Spliceosome mRNA Splicing - Major Pathway
		CRTC3	Unknown	34185311	Open Targets	Human T-cell leukemia virus 1 infection Transcriptional activation of mitochondrial biogenesis Circadian Clock
		CSF1R	Unknown	34045664	Open Targets	MAPK signaling pathway Ras signaling pathway Rap1 signaling pathway +10 more
		CSF3R	Unknown	34045664	Open Targets	Cytokine-cytokine receptor interaction PI3K-Akt signaling pathway JAK-STAT signaling pathway +3 more
		CSMD3	Unknown	34045664	Open Targets	—
		CTCF	Unknown	34045664	Open Targets	—
		CTNNA1	Unknown	34045664	Open Targets	Hippo signaling pathway Adherens junction Leukocyte transendothelial migration +9 more
		CTNNA2	Unknown	34045664	Open Targets	Hippo signaling pathway Adherens junction Leukocyte transendothelial migration +6 more
		CTNND2	Unknown	34045664	Open Targets	Wnt signaling pathway
		CUX1	Unknown	34045664	Open Targets	Signaling by cytosolic FGFR1 fusion mutants Signaling by FGFR1 in disease Intra-Golgi traffic
		CYP2C8	Unknown	34045664	Open Targets	Arachidonic acid metabolism Linoleic acid metabolism Retinol metabolism +10 more
		DAXX	Unknown	34045664	Open Targets	MAPK signaling pathway Apoptosis Parkinson disease +6 more
		DCC	Unknown	34045664	Open Targets	Axon guidance Pathways in cancer Colorectal cancer +3 more
		DDR2	Unknown	31145701 34045664	Open Targets	Non-integrin membrane-ECM interactions
		DDX10	Unknown	34045664	Open Targets	—
		DDX3X	Unknown	34045664	Open Targets	RIG-I-like receptor signaling pathway Hepatitis B Viral carcinogenesis +1 more
		DDX6	Unknown	34045664	Open Targets	RNA degradation mRNA decay by 5' to 3' exoribonuclease
		DGCR8	Unknown	34045664	Open Targets	MicroRNA (miRNA) biogenesis

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Eccrine porocarcinoma

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