Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
DUPUYTREN CONTRACTURE	EFO_0004229	ACAN	Unknown	21732829 28886342 37315093 38172110 39024449	GWAS catalog	Degradation of the extracellular matrix Keratan sulfate biosynthesis Keratan sulfate degradation +4 more
		ADCY4	Unknown	37315093	GWAS catalog	Purine metabolism Metabolic pathways Endocrine resistance +59 more
		AFAP1	Unknown	38172110 39024449	GWAS catalog	—
		ANTXR1	Unknown	37315093 38172110	GWAS catalog	NOD-like receptor signaling pathway Uptake and function of anthrax toxins
		ATE1	Unknown	28886342 38172110 39024449	GWAS catalog	—
		ATL1	Unknown	28886342 39024449	GWAS catalog	—
		ATP9A	Unknown	37315093 38172110 39024449	GWAS catalog	Ion transport by P-type ATPases
		ATXN10	Unknown	38172110	GWAS catalog	Spinocerebellar ataxia
		BABAM2	Unknown	38172110	GWAS catalog	Homologous recombination Metalloprotease DUBs Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks +3 more
		BOP1	Unknown	28886342 38172110	GWAS catalog	Major pathway of rRNA processing in the nucleolus and cytosol
		C8ORF34	Unknown	38172110	GWAS catalog	—
		CDK8	Unknown	37315093	GWAS catalog	PPARA activates gene expression Generic Transcription Pathway SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription +3 more
		CDKL1	Unknown	37315093	GWAS catalog	—
		CFDP1	Unknown	37315093 38172110	GWAS catalog	—
		CFTR	Unknown	38172110	GWAS catalog	ABC transporters cAMP signaling pathway AMPK signaling pathway +12 more
		CHST6	Unknown	28886342 39024449	GWAS catalog	Glycosaminoglycan biosynthesis - keratan sulfate Keratan sulfate biosynthesis Defective CHST6 causes MCDC1
		CHSY1	Unknown	38172110	GWAS catalog	Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate Metabolic pathways Chondroitin sulfate biosynthesis +1 more
		DCD	Unknown	39024449	GWAS catalog	Antimicrobial peptides
		DCHS2	Unknown	37315093	GWAS catalog	Hippo signaling pathway - multiple species
		DDR2	Unknown	28886342 37315093 38172110 39024449	GWAS catalog	Non-integrin membrane-ECM interactions
		DHX8	Unknown	28886342	GWAS catalog	Spliceosome
		DSTYK	Unknown	38172110 39024449	GWAS catalog	—
		DUSP10	Unknown	20971583	GWAS catalog	MAPK signaling pathway RAF-independent MAPK1/3 activation Negative regulation of MAPK pathway
		DUXA	Unknown	21732829 28886342 37315093 38172110 39024449	GWAS catalog	—
		EBF2	Unknown	28886342 37315093 38172110 39024449	GWAS catalog	—
		EIF3E	Unknown	21732829 28886342	GWAS catalog	Hepatitis C L13a-mediated translational silencing of Ceruloplasmin expression Translation initiation complex formation +4 more
		ELL	Unknown	37315093 38172110 39024449	GWAS catalog	Viral life cycle - HIV-1 Formation of RNA Pol II elongation complex RNA Polymerase II Pre-transcription Events +4 more
		ELMO1	Unknown	38172110	GWAS catalog	Chemokine signaling pathway Efferocytosis Bacterial invasion of epithelial cells +8 more
		EMC2	Unknown	38172110	GWAS catalog	—
		EPDR1	Unknown	21732829 28886342 38172110	GWAS catalog	—
		ERG	Unknown	37315093 38172110 39024449	GWAS catalog	Transcriptional misregulation in cancer Prostate cancer
		EXOC2	Unknown	38172110	GWAS catalog	Ras signaling pathway Salmonella infection Insulin processing +1 more
		FER	Unknown	38172110 39024449	GWAS catalog	Adherens junction Signaling by SCF-KIT
		FGFR2	Unknown	28886342 37315093 38172110 39024449	GWAS catalog	EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway Ras signaling pathway +26 more
		FMN2	Unknown	39024449	GWAS catalog	Cytoskeleton in muscle cells
		GLIS3	Unknown	37315093	GWAS catalog	—
		HS3ST3A1	Unknown	37315093 38172110	GWAS catalog	Glycosaminoglycan biosynthesis - heparan sulfate / heparin HS-GAG biosynthesis
		IRF1	Unknown	37315093	GWAS catalog	C-type lectin receptor signaling pathway TNF signaling pathway Prolactin signaling pathway +5 more
		ISG20	Unknown	21732829 28886342 37315093 38172110 39024449	GWAS catalog	Interferon alpha/beta signaling
		ITGA11	Unknown	28886342 37315093 38172110	GWAS catalog	PI3K-Akt signaling pathway Focal adhesion ECM-receptor interaction +7 more
		JAG1	Unknown	37315093 39024449	GWAS catalog	Endocrine resistance Notch signaling pathway Apelin signaling pathway +12 more
		KDR	Unknown	37315093 38172110 39024449	GWAS catalog	EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway Ras signaling pathway +13 more
		KLHL6	Unknown	37315093	GWAS catalog	—
		LIMD1	Unknown	38172110	GWAS catalog	Hippo signaling pathway Hippo signaling pathway - multiple species Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
		LPP	Unknown	38172110	GWAS catalog	—
		LRRK1	Unknown	37315093	GWAS catalog	—
		MAFB	Unknown	21732829 28886342 37315093 38172110 39024449	GWAS catalog	Parathyroid hormone synthesis, secretion and action
		MAP4K5	Unknown	38172110	GWAS catalog	—
		MEOX1	Unknown	38172110	GWAS catalog	—
		MICAL2	Unknown	38172110	GWAS catalog	—

«‹12 ›»

Dupuytren contracture

Bookmark This Disease