Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
CARDIOMYOPATHY, DILATED	C0007193 MESH:D002311	RPL3L	Unknown	—	Disgenet	Ribosome Coronavirus disease - COVID-19 L13a-mediated translational silencing of Ceruloplasmin expression +7 more
		RYR2	Unknown	—	Disgenet	Calcium signaling pathway cAMP signaling pathway Cardiac muscle contraction +14 more
		SCN2B	Unknown	—	Disgenet	Phase 0 - rapid depolarisation
		SCN4B	Unknown	—	Disgenet	Adrenergic signaling in cardiomyocytes Phase 0 - rapid depolarisation
		SCN5A	Unknown	—	Disgenet	Adrenergic signaling in cardiomyocytes Phase 0 - rapid depolarisation
		SCO2	Unknown	—	Disgenet	Central carbon metabolism in cancer TP53 Regulates Metabolic Genes Respiratory electron transport
		SDHA	Unknown	—	CTD, Disgenet	Citrate cycle (TCA cycle) Oxidative phosphorylation Metabolic pathways +12 more
		SGCB	Unknown	—	Disgenet	Cytoskeleton in muscle cells Hypertrophic cardiomyopathy Arrhythmogenic right ventricular cardiomyopathy +2 more
		SGCD	Unknown	—	Disgenet	Cytoskeleton in muscle cells Hypertrophic cardiomyopathy Arrhythmogenic right ventricular cardiomyopathy +2 more
		SHBG	Unknown	25996886	CTD, Disgenet	—
		SIK1	Unknown	16243910	CTD, Disgenet	Glucagon signaling pathway
		SLC22A5	Unknown	21641380	CTD, Disgenet	Choline metabolism in cancer Carnitine metabolism Organic cation transport +1 more
		SLC25A4	Unknown	—	Disgenet	Calcium signaling pathway cGMP-PKG signaling pathway Necroptosis +15 more
		SLC30A5	Unknown	—	Disgenet	Insulin processing Zinc efflux and compartmentalization by the SLC30 family
		SOD2	Unknown	16155095 21195081	CTD, Disgenet	FoxO signaling pathway Peroxisome Longevity regulating pathway +9 more
		SOS1	Unknown	—	Disgenet	EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +97 more
		SP4	Unknown	—	Disgenet	—
		STK38	Unknown	—	Disgenet	—
		SYNE1	Unknown	—	Disgenet	Cytoskeleton in muscle cells
		SYNE2	Unknown	—	Disgenet	Cytoskeleton in muscle cells
		TAB2	Unknown	—	Disgenet	MAPK signaling pathway NF-kappa B signaling pathway Osteoclast differentiation +33 more
		TAF10	Unknown	—	Disgenet	Basal transcription factors Ub-specific processing proteases RNA Polymerase II Pre-transcription Events +5 more
		TAF1A	Unknown	—	Disgenet	B-WICH complex positively regulates rRNA expression RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Escape +1 more
		TAFAZZIN	Unknown	—	Disgenet	Glycerophospholipid metabolism
		TBX20	Unknown	—	Disgenet	—
		TBX5	Unknown	32449309 25963046 32236096 25725155	Disgenet	YAP1- and WWTR1 (TAZ)-stimulated gene expression Physiological factors
		TCAP	Unknown	—	Disgenet	Cytoskeleton in muscle cells Striated Muscle Contraction
		TCF7L2	Unknown	29394407	CTD, Disgenet	Wnt signaling pathway Hippo signaling pathway Adherens junction +26 more
		TJP1	Unknown	—	Disgenet	Adherens junction Tight junction Gap junction +7 more
		TMEM43	Unknown	—	Disgenet	Cytoskeleton in muscle cells
		TMOD1	Unknown	—	Disgenet	Cytoskeleton in muscle cells Striated Muscle Contraction
		TMPO	Unknown	16247757	CTD, Disgenet	Nuclear Envelope Breakdown Initiation of Nuclear Envelope (NE) Reformation Depolymerisation of the Nuclear Lamina
		TNFRSF4	Unknown	12031769	CTD, Disgenet	Cytokine-cytokine receptor interaction TNFs bind their physiological receptors
		TNFRSF8	Unknown	12031769	CTD, Disgenet	Cytokine-cytokine receptor interaction TNFs bind their physiological receptors
		TNFRSF9	Unknown	12031769	CTD, Disgenet	Cytokine-cytokine receptor interaction TNFs bind their physiological receptors
		TNFSF4	Unknown	12031769	CTD, Disgenet	Cytokine-cytokine receptor interaction TNFs bind their physiological receptors
		TNFSF8	Unknown	12031769	CTD, Disgenet	Cytokine-cytokine receptor interaction TNFs bind their physiological receptors
		TNFSF9	Unknown	12031769	CTD, Disgenet	Cytokine-cytokine receptor interaction TNFs bind their physiological receptors
		TNNC1	Unknown	—	Disgenet	Calcium signaling pathway Cardiac muscle contraction Adrenergic signaling in cardiomyocytes +5 more
		TNNI3	Unknown	15070570	CTD, Disgenet	cAMP signaling pathway Cardiac muscle contraction Adrenergic signaling in cardiomyocytes +7 more
		TNNI3K	Unknown	—	Disgenet	—
		TNNT2	Unknown	17556660 19477965	CTD, Disgenet	Cardiac muscle contraction Adrenergic signaling in cardiomyocytes Motor proteins +4 more
		TPM1	Unknown	—	Disgenet	Cardiac muscle contraction Adrenergic signaling in cardiomyocytes Motor proteins +6 more
		TRPM4	Unknown	—	Disgenet	Insulin secretion TRP channels
		TSFM	Unknown	—	Disgenet	—
		TTN	Unknown	11846417 17444505 27869827	CTD, Disgenet	Cytoskeleton in muscle cells Hypertrophic cardiomyopathy Dilated cardiomyopathy +2 more
		TUBB	Unknown	—	Disgenet	Phagosome Gap junction Motor proteins +16 more
		TXNRD2	Unknown	—	Disgenet	Selenocompound metabolism Pathways in cancer Hepatocellular carcinoma +1 more
		UCP1	Unknown	26670611	CTD, Disgenet	PPAR signaling pathway Apelin signaling pathway Thermogenesis +3 more
		VCL	Unknown	—	Disgenet	Focal adhesion Adherens junction Leukocyte transendothelial migration +14 more
CARDIOMYOPATHY, DILATED, 1B	C5700078	TTN	Unknown	—	Disgenet	Cytoskeleton in muscle cells Hypertrophic cardiomyopathy Dilated cardiomyopathy +2 more
CARDIOMYOPATHY, DILATED, 1C	C1832244	RYR2	Unknown	—	Disgenet	Calcium signaling pathway cAMP signaling pathway Cardiac muscle contraction +14 more
CARDIOMYOPATHY, DILATED, 1D	601494 C1832243 MESH:C563306	TNNT2	Unknown	—	CTD, Disgenet, HPO	Cardiac muscle contraction Adrenergic signaling in cardiomyocytes Motor proteins +4 more
CARDIOMYOPATHY, DILATED, 1DD	C2750995	TNNT2	Unknown	—	Disgenet	Cardiac muscle contraction Adrenergic signaling in cardiomyocytes Motor proteins +4 more
CARDIOMYOPATHY, DILATED, 1E	601154 C1832680 MESH:C563384	SCN5A	Unknown	—	CTD, Disgenet, HPO	Adrenergic signaling in cardiomyocytes Phase 0 - rapid depolarisation
CARDIOMYOPATHY, DILATED, 1FF	613286 C2750091 MESH:C567654	TNNI3	Unknown	—	CTD, Disgenet, HPO	cAMP signaling pathway Cardiac muscle contraction Adrenergic signaling in cardiomyocytes +7 more
CARDIOMYOPATHY, DILATED, 1G	604145 C1858763 MESH:C565824	TTN	Unknown	—	CTD, Disgenet, HPO	Cytoskeleton in muscle cells Hypertrophic cardiomyopathy Dilated cardiomyopathy +2 more
CARDIOMYOPATHY, DILATED, 1GG	613642 C3150898	SDHA	Unknown	—	Disgenet, HPO	Citrate cycle (TCA cycle) Oxidative phosphorylation Metabolic pathways +12 more
CARDIOMYOPATHY, DILATED, 1H	C1858591	SLC25A4	Unknown	—	Disgenet	Calcium signaling pathway cGMP-PKG signaling pathway Necroptosis +15 more
CARDIOMYOPATHY, DILATED, 1L	606685 C1847667 MESH:C564679	SGCD	Unknown	—	CTD, Disgenet, HPO	Cytoskeleton in muscle cells Hypertrophic cardiomyopathy Arrhythmogenic right ventricular cardiomyopathy +2 more
CARDIOMYOPATHY, DILATED, 1N	MESH:C564388	TCAP	Unknown	—	CTD	Cytoskeleton in muscle cells Striated Muscle Contraction
CARDIOMYOPATHY, DILATED, 1S	C1834481	TNNC1	Unknown	—	Disgenet	Calcium signaling pathway Cardiac muscle contraction Adrenergic signaling in cardiomyocytes +5 more
		TNNT2	Unknown	—	Disgenet	Cardiac muscle contraction Adrenergic signaling in cardiomyocytes Motor proteins +4 more
		TTN	Unknown	—	Disgenet	Cytoskeleton in muscle cells Hypertrophic cardiomyopathy Dilated cardiomyopathy +2 more
		VCL	Unknown	—	Disgenet	Focal adhesion Adherens junction Leukocyte transendothelial migration +14 more
CARDIOMYOPATHY, DILATED, 1T	C3151039	TMPO	Unknown	—	Disgenet	Nuclear Envelope Breakdown Initiation of Nuclear Envelope (NE) Reformation Depolymerisation of the Nuclear Lamina
CARDIOMYOPATHY, DILATED, 1W	611407 C1969639 MESH:C566954	VCL	Unknown	—	CTD, Disgenet, HPO	Focal adhesion Adherens junction Leukocyte transendothelial migration +14 more
CARDIOMYOPATHY, DILATED, 1Y	611878 C2678476 MESH:C567507	TPM1	Unknown	—	CTD, Disgenet, HPO	Cardiac muscle contraction Adrenergic signaling in cardiomyocytes Motor proteins +6 more
CARDIOMYOPATHY, DILATED, 1Z	611879 C2678475 MESH:C567506	TNNC1	Unknown	—	CTD, Disgenet, HPO	Calcium signaling pathway Cardiac muscle contraction Adrenergic signaling in cardiomyocytes +5 more
CARDIOMYOPATHY, DILATED, 2A	611880 C2678474 MESH:C567505	TNNI3	Unknown	—	CTD, Disgenet, HPO	cAMP signaling pathway Cardiac muscle contraction Adrenergic signaling in cardiomyocytes +7 more
CARDIOMYOPATHY, DILATED, WITH LEFT VENTRICULAR NONCOMPACTION	C1853863	RYR2	Unknown	—	Disgenet	Calcium signaling pathway cAMP signaling pathway Cardiac muscle contraction +14 more
	C1853863	VCL	Unknown	—	Disgenet	Focal adhesion Adherens junction Leukocyte transendothelial migration +14 more
DILATED CARDIOMYOPATHY	MONDO:0005021 EFO_0000407	RPL3L	Unknown	32514796 32870709 35323613 36291431 37080962 37308880 38254943	ClinGen, GenCC	Ribosome Coronavirus disease - COVID-19 L13a-mediated translational silencing of Ceruloplasmin expression +7 more
		RYR2	Unknown	1318794 21099115 2226801 31931689 38479959 38621141	ClinGen, GWAS catalog	Calcium signaling pathway cAMP signaling pathway Cardiac muscle contraction +14 more
		SCN5A	Unknown	15671429 17512504 19808398 20458009 21596231 21824921 22675453 22766342 22999724 29506689 29871609 30218094 31514951 31520233 31930659	ClinGen, GWAS catalog	Adrenergic signaling in cardiomyocytes Phase 0 - rapid depolarisation
		SLC30A5	Unknown	—	GenCC	Insulin processing Zinc efflux and compartmentalization by the SLC30 family
		SOD2	Unknown	31494578	GWAS catalog	FoxO signaling pathway Peroxisome Longevity regulating pathway +9 more
		TBX20	Unknown	10936053 14550786 15843414 17668378 19074289 21890625 26118961 26895318 27510170 28945738 30384889 37657916 38353104	ClinGen, GWAS catalog	—
		TCAP	Unknown	15582318 19412328 23100327 24037902 26084686 27532257 34011823 39226992 9350988 9817758	CTD, ClinGen	Cytoskeleton in muscle cells Striated Muscle Contraction
		TMOD1	Unknown	11352937 20736303 2380244 38168645 8661028 9421465 9440708	ClinGen, GWAS catalog	Cytoskeleton in muscle cells Striated Muscle Contraction
		TNNC1	Unknown	15542288 17977476 18212018 19609041 20458010 20566645 21483645 21832052 2250022 24558114 26379556 26458567 31748410 31983221 32038292 4634985	ClinGen, GenCC	Calcium signaling pathway Cardiac muscle contraction Adrenergic signaling in cardiomyocytes +5 more
		TNNI3	Unknown	15070570 19590045 20215591 20817590 21846512 2226790 22464770 23539503 24503780 26406308 27532257 28436080 29093449 31568572 31983221 34036930 34213952 35838873 36157491 36252119	ClinGen, GWAS catalog	cAMP signaling pathway Cardiac muscle contraction Adrenergic signaling in cardiomyocytes +7 more
		TNNI3K	Unknown	12721663 19763165 23085512 24925317 25791106 29355681 30010057 33084860 35781726 37628941 38424693	ClinGen, GWAS catalog	—
		TNNT2	Unknown	11106718 11684629 11967535 15542288 17556660 17932326 20031601 20978592 8088824	ClinGen, GWAS catalog	Cardiac muscle contraction Adrenergic signaling in cardiomyocytes Motor proteins +4 more
		TPM1	Unknown	11273725 15249230 20117437 20215591 21483645 23147248 25548289 28600229 31643006 31983221 35029218 36739943 39684770	ClinGen, GWAS catalog	Cardiac muscle contraction Adrenergic signaling in cardiomyocytes Motor proteins +6 more
		TTN	Unknown	11788824 11788825 16733766 19406126 22335739 23418287 24119082 25589632 25759365 26084686 26315439 27437901 27869827 28045975 29093449 33495596 39572784	ClinGen, ClinVar, GWAS catalog	Cytoskeleton in muscle cells Hypertrophic cardiomyopathy Dilated cardiomyopathy +2 more
		TXNRD2	Unknown	—	GenCC	Selenocompound metabolism Pathways in cancer Hepatocellular carcinoma +1 more
		VCL	Unknown	10320340 11815424 17785437 24062880 26406308 26458567 30900782 31983221 32516855 34386585 35284542 37477868 37548861 6789327 8994410	ClinGen, Disgenet	Focal adhesion Adherens junction Leukocyte transendothelial migration +14 more
DILATED CARDIOMYOPATHY 1T		TMPO	Unknown	—	ClinVar	Nuclear Envelope Breakdown Initiation of Nuclear Envelope (NE) Reformation Depolymerisation of the Nuclear Lamina
DILATED CARDIOMYOPATHY 1W	MONDO:0012667	VCL	Unknown	11815424 17785437 20474083 24062880 24503780 25163546 26458567 26573135 27532257 30165862 30609409 30923642 32516855	ClinVar, GWAS catalog	Focal adhesion Adherens junction Leukocyte transendothelial migration +14 more
FAMILIAL DILATED CARDIOMYOPATHY	C0340427 MESH:C536231	RYR2	Unknown	—	Disgenet, ClinGen	Calcium signaling pathway cAMP signaling pathway Cardiac muscle contraction +14 more
		SCN5A	Unknown	—	Disgenet	Adrenergic signaling in cardiomyocytes Phase 0 - rapid depolarisation
		SGCD	Unknown	—	Disgenet	Cytoskeleton in muscle cells Hypertrophic cardiomyopathy Arrhythmogenic right ventricular cardiomyopathy +2 more
		TAFAZZIN	Unknown	—	Disgenet	Glycerophospholipid metabolism
		TNNI3	Unknown	—	Disgenet	cAMP signaling pathway Cardiac muscle contraction Adrenergic signaling in cardiomyocytes +7 more
		TNNT2	Unknown	—	Disgenet	Cardiac muscle contraction Adrenergic signaling in cardiomyocytes Motor proteins +4 more
		TTN	Unknown	11788824	CTD, Disgenet	Cytoskeleton in muscle cells Hypertrophic cardiomyopathy Dilated cardiomyopathy +2 more
		VCL	Unknown	—	Disgenet	Focal adhesion Adherens junction Leukocyte transendothelial migration +14 more
FAMILIAL ISOLATED DILATED CARDIOMYOPATHY	154 MONDO:0015470	RPL3L	Unknown	32514796	Orphanet	Ribosome Coronavirus disease - COVID-19 L13a-mediated translational silencing of Ceruloplasmin expression +7 more
		SCN5A	Unknown	15466643 22766342 20301486	GWAS catalog, Orphanet	Adrenergic signaling in cardiomyocytes Phase 0 - rapid depolarisation
		SDHA	Unknown	20551992	GWAS catalog, Orphanet	Citrate cycle (TCA cycle) Oxidative phosphorylation Metabolic pathways +12 more
		SGCD	Unknown	10974018 20301486	GWAS catalog, Orphanet	Cytoskeleton in muscle cells Hypertrophic cardiomyopathy Arrhythmogenic right ventricular cardiomyopathy +2 more
		TAF1A	Unknown	28472305	GWAS catalog, Orphanet	B-WICH complex positively regulates rRNA expression RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Escape +1 more
		TAFAZZIN	Unknown	20301486 7616547 9382096	Orphanet	Glycerophospholipid metabolism
		TCAP	Unknown	15582318 19412328 20301486	Disgenet, Orphanet	Cytoskeleton in muscle cells Striated Muscle Contraction
		TMPO	Unknown	16247757 20301486	CTD, Orphanet	Nuclear Envelope Breakdown Initiation of Nuclear Envelope (NE) Reformation Depolymerisation of the Nuclear Lamina
		TNNC1	Unknown	15542288 20301486	GWAS catalog, Orphanet	Calcium signaling pathway Cardiac muscle contraction Adrenergic signaling in cardiomyocytes +5 more
		TNNI3	Unknown	15070570 19590045 20301486	Disgenet, Orphanet	cAMP signaling pathway Cardiac muscle contraction Adrenergic signaling in cardiomyocytes +7 more
		TPM1	Unknown	11273725 20301486	GWAS catalog, Orphanet	Cardiac muscle contraction Adrenergic signaling in cardiomyocytes Motor proteins +6 more
		TTN	Unknown	11788824 20301486	GWAS catalog, Orphanet	Cytoskeleton in muscle cells Hypertrophic cardiomyopathy Dilated cardiomyopathy +2 more
		TXNRD2	Unknown	21247928	GWAS catalog, Orphanet	Selenocompound metabolism Pathways in cancer Hepatocellular carcinoma +1 more
		VCL	Unknown	11815424 20301486	GWAS catalog, Orphanet	Focal adhesion Adherens junction Leukocyte transendothelial migration +14 more
FAMILIAL OR IDIOPATHIC DILATED CARDIOMYOPATHY	C5679590	RPL3L	Unknown	—	Disgenet	Ribosome Coronavirus disease - COVID-19 L13a-mediated translational silencing of Ceruloplasmin expression +7 more
		SCN5A	Unknown	15466643 15671429 19808398 21596231 22675453 22999724 26916278 27532257 30847666	Disgenet	Adrenergic signaling in cardiomyocytes Phase 0 - rapid depolarisation
		SDHA	Unknown	—	Disgenet	Citrate cycle (TCA cycle) Oxidative phosphorylation Metabolic pathways +12 more
		SGCD	Unknown	—	Disgenet	Cytoskeleton in muscle cells Hypertrophic cardiomyopathy Arrhythmogenic right ventricular cardiomyopathy +2 more
		TAF1A	Unknown	—	Disgenet	B-WICH complex positively regulates rRNA expression RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Escape +1 more
		TAFAZZIN	Unknown	—	Disgenet	Glycerophospholipid metabolism
		TCAP	Unknown	—	Disgenet	Cytoskeleton in muscle cells Striated Muscle Contraction
		TMPO	Unknown	—	Disgenet	Nuclear Envelope Breakdown Initiation of Nuclear Envelope (NE) Reformation Depolymerisation of the Nuclear Lamina
		TNNC1	Unknown	1554228 17021793 17977476 18212018 18803402 19808376 20458010 27532257 27604170 32038292	Disgenet	Calcium signaling pathway Cardiac muscle contraction Adrenergic signaling in cardiomyocytes +5 more
		TNNI3	Unknown	—	Disgenet	cAMP signaling pathway Cardiac muscle contraction Adrenergic signaling in cardiomyocytes +7 more
		TNNT2	Unknown	—	Disgenet	Cardiac muscle contraction Adrenergic signaling in cardiomyocytes Motor proteins +4 more
		TPM1	Unknown	—	Disgenet	Cardiac muscle contraction Adrenergic signaling in cardiomyocytes Motor proteins +6 more
		TTN	Unknown	—	Disgenet	Cytoskeleton in muscle cells Hypertrophic cardiomyopathy Dilated cardiomyopathy +2 more
		TXNRD2	Unknown	—	Disgenet	Selenocompound metabolism Pathways in cancer Hepatocellular carcinoma +1 more
		VCL	Unknown	—	Disgenet	Focal adhesion Adherens junction Leukocyte transendothelial migration +14 more
PRIMARY DILATED CARDIOMYOPATHY		SGCD	Unknown	33947203	ClinVar	Cytoskeleton in muscle cells Hypertrophic cardiomyopathy Arrhythmogenic right ventricular cardiomyopathy +2 more
PRIMARY DILATED CARDIOMYOPATHY		TMPO	Unknown	—	ClinVar	Nuclear Envelope Breakdown Initiation of Nuclear Envelope (NE) Reformation Depolymerisation of the Nuclear Lamina

«‹1 2 345 6 ›»

Dilated cardiomyopathy

Bookmark This Disease