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Congenital aneurysm of ascending aorta
Congenital aneurysm of ascending aorta
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Pathways column key:
KEGG
Reactome
Disease Term
Disease ID
Gene Symbol
Classification
References
Source
Pathways
CONGENITAL ANEURYSM OF ASCENDING AORTA
C0345050
COL3A1
Causal
—
Disgenet
Platelet activation
Cytoskeleton in muscle cells
Relaxin signaling pathway
AGE-RAGE signaling pathway in diabetic complications
Protein digestion and absorption
Amoebiasis
Diabetic cardiomyopathy
Collagen degradation
Extracellular matrix organization
Collagen biosynthesis and modifying enzymes
Signaling by PDGF
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Assembly of collagen fibrils and other multimeric structures
Integrin cell surface interactions
Non-integrin membrane-ECM interactions
ECM proteoglycans
NCAM1 interactions
MET activates PTK2 signaling
Collagen chain trimerization
+16 more
FBN1
Causal
—
Disgenet
TGF-beta signaling pathway
Cytoskeleton in muscle cells
Degradation of the extracellular matrix
Elastic fibre formation
Molecules associated with elastic fibres
Integrin cell surface interactions
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Post-translational protein phosphorylation
+5 more
LOX
Causal
—
Disgenet
Elastic fibre formation
Crosslinking of collagen fibrils
All
12
Causal
3
Unknown
9
Select all
Clear
ClinVar
0
Orphanet
0
Disgenet
3
CTD
0
HPO
0
GWAS catalog
0
GenCC
0
ClinGen
0
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Aortic dissection
7 shared genes
FBN1, SMAD3, FOXE3, COL3A1, TGFBR2, LOX, SRFBP1
Related via 7 shared genes including FBN1, SMAD3, FOXE3.
Loeys-dietz syndrome
6 shared genes
FBN1, SMAD3, COL3A1, MYH11, TGFBR2, MYLK
Related via 6 shared genes including FBN1, SMAD3, COL3A1.
familial thoracic aortic aneurysm and aortic dissection
5 shared genes
FBN1, FOXE3, MYH11, LOX, MYLK
Related via 5 shared genes including FBN1, FOXE3, MYH11.
Thoracic aortic aneurysm and aortic dissection
10 shared genes
FBN1, SMAD3, FOXE3, COL3A1, MYH11, NDE1, TGFBR2, LOX, SRFBP1, MYLK
Related via 10 shared genes including FBN1, SMAD3, FOXE3.
Megacystis microcolon intestinal hypoperistalsis syndrome
3 shared genes
MYH11, NDE1, MYLK
Related via 3 shared genes including MYH11, NDE1, MYLK.
1
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