Combined hepatocellular carcinoma and cholangiocarcinoma | Gene-Disease Associations & Pathways | GeDiPNet

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Subtype of: Hepatocellular carcinoma

Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
combined hepatocellular carcinoma and cholangiocarcinoma	MONDO_0044791	TLX3	Unknown	37267699	Open Targets	Transcriptional misregulation in cancer
		TNC	Unknown	37699724	Open Targets	PI3K-Akt signaling pathway Focal adhesion ECM-receptor interaction +6 more
		TP53	Unknown	37267699 32952556 29497050 28126467 29976634 34234458 37699724 27252594 28481359	Open Targets	Endocrine resistance Platinum drug resistance MAPK signaling pathway +85 more
		TSC1	Unknown	37267699	Open Targets	Phospholipase D signaling pathway Autophagy - animal mTOR signaling pathway +15 more
		TSC2	Unknown	28481359	Open Targets	Phospholipase D signaling pathway p53 signaling pathway Autophagy - animal +19 more
		TSHR	Unknown	28481359	Open Targets	cAMP signaling pathway Neuroactive ligand-receptor interaction Hormone signaling +6 more
		USP9X	Unknown	37267699	Open Targets	Downregulation of SMAD2/3:SMAD4 transcriptional activity Ub-specific processing proteases Synthesis of active ubiquitin: roles of E1 and E2 enzymes +2 more
		WNK2	Unknown	37267699 29497050 37699724	Open Targets	Parathyroid hormone synthesis, secretion and action Stimuli-sensing channels
		XPO1	Unknown	32952556	Open Targets	Ribosome biogenesis in eukaryotes Nucleocytoplasmic transport Viral life cycle - HIV-1 +15 more
		ZFHX3	Unknown	37267699 29497050 32952556	Open Targets	Signaling pathways regulating pluripotency of stem cells RUNX3 regulates CDKN1A transcription
		ZMYM3	Unknown	29497050	Open Targets	—
		ZNF521	Unknown	37699724	Open Targets	—

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