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Cancer predisposition
Cancer predisposition
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Pathways column key:
KEGG
Reactome
Disease Term
Disease ID
Gene Symbol
Classification
References
Source
Pathways
HAVCR2-related cancer predisposition
HAVCR2
Unknown
—
ClinGen
Efferocytosis
RAD51D-related cancer predisposition
RAD51D
Unknown
—
ClinGen
Homologous recombination
HDR through Homologous Recombination (HRR)
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)
Resolution of D-loop Structures through Holliday Junction Intermediates
Homologous DNA Pairing and Strand Exchange
Presynaptic phase of homologous DNA pairing and strand exchange
TP53 Regulates Transcription of DNA Repair Genes
+4 more
All
9
Causal
7
Unknown
2
Select all
Clear
ClinVar
0
Orphanet
0
Disgenet
0
CTD
0
HPO
0
GWAS catalog
0
GenCC
0
ClinGen
2
Open Targets
0
Related Diseases
Diseases that share the most curated genes with Cancer predisposition.
5
View disease cluster →
Hereditary breast and ovarian cancer syndrome
8 shared genes
CHEK2, ATM, BARD1, PALB2, BRCA2, BRCA1, RAD51C, RAD51D
Related via 8 shared genes including CHEK2, ATM, BARD1.
Familial ovarian cancer
5 shared genes
PALB2, BRCA2, BRCA1, RAD51C, RAD51D
Related via 5 shared genes including PALB2, BRCA2, BRCA1.
Primary peritoneal serous adenocarcinoma
2 shared genes
ATM, BRCA2
Related via 2 shared genes including ATM, BRCA2.
Hereditary breast cancer
6 shared genes
CHEK2, ATM, BARD1, PALB2, BRCA2, BRCA1
Related via 6 shared genes including CHEK2, ATM, BARD1.
Breast implant-associated anaplastic large cell lymphoma
2 shared genes
BRCA2, BRCA1
Related via 2 shared genes including BRCA2, BRCA1.
1
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