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Breast and ovarian cancer
Breast and ovarian cancer
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Include the contents of this disease's 1 subtype
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Show the subtype
Hereditary breast and ovarian cancer syndrome
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Pathways column key:
KEGG
Reactome
Disease Term
Disease ID
Gene Symbol
Classification
References
Source
Pathways
Breast and Ovarian Cancer
MONDO_0003582
PALB2
Unknown
17200668
19264984
23448497
22241545
24556926
17200672
25337758
33811135
25099575
17287723
18053174
32546565
31841383
Open Targets
Homologous recombination
Fanconi anemia pathway
HDR through Homologous Recombination (HRR)
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)
Resolution of D-loop Structures through Holliday Junction Intermediates
Homologous DNA Pairing and Strand Exchange
+3 more
PTEN
Unknown
22252256
Open Targets
Inositol phosphate metabolism
Metabolic pathways
EGFR tyrosine kinase inhibitor resistance
FoxO signaling pathway
Phosphatidylinositol signaling system
Sphingolipid signaling pathway
p53 signaling pathway
Autophagy - animal
mTOR signaling pathway
PI3K-Akt signaling pathway
Cellular senescence
Focal adhesion
Insulin resistance
Human papillomavirus infection
Human T-cell leukemia virus 1 infection
Pathways in cancer
MicroRNAs in cancer
Chemical carcinogenesis - reactive oxygen species
Endometrial cancer
Glioma
Prostate cancer
Melanoma
Small cell lung cancer
Breast cancer
Hepatocellular carcinoma
Central carbon metabolism in cancer
PD-L1 expression and PD-1 checkpoint pathway in cancer
Diabetic cardiomyopathy
Synthesis of PIPs at the plasma membrane
Synthesis of IP3 and IP4 in the cytosol
Negative regulation of the PI3K/AKT network
Downstream TCR signaling
TP53 Regulates Metabolic Genes
PTEN Loss of Function in Cancer
Ub-specific processing proteases
Ovarian tumor domain proteases
Regulation of PTEN mRNA translation
Regulation of PTEN localization
Regulation of PTEN stability and activity
Transcriptional Regulation by MECP2
+37 more
STK11
Unknown
11113065
Open Targets
FoxO signaling pathway
Hormone signaling
Autophagy - animal
mTOR signaling pathway
PI3K-Akt signaling pathway
AMPK signaling pathway
Longevity regulating pathway
Tight junction
Adipocytokine signaling pathway
Energy dependent regulation of mTOR by LKB1-AMPK
Regulation of TP53 Activity through Phosphorylation
FOXO-mediated transcription of cell death genes
+9 more
All
3
Causal
0
Unknown
3
Select all
Clear
ClinVar
0
Orphanet
0
Disgenet
0
CTD
0
HPO
0
GWAS catalog
0
GenCC
0
ClinGen
0
Open Targets
3
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