Brain stem glioblastoma | Gene-Disease Associations & Pathways | GeDiPNet

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Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
Brain Stem Glioblastoma	EFO_1000141	TNRC18	Unknown	24705252 24880341	Open Targets	—
		TP53	Unknown	24705252 28401334 34625582 24880341 24705251	Open Targets	Endocrine resistance Platinum drug resistance MAPK signaling pathway +85 more
		TPM3	Unknown	24705251	Open Targets	Cardiac muscle contraction Adrenergic signaling in cardiomyocytes Motor proteins +7 more
		TPR	Unknown	24705251	Open Targets	Nucleocytoplasmic transport Amyotrophic lateral sclerosis Pathways in cancer +27 more
		TRIP11	Unknown	24705251	Open Targets	Intraflagellar transport Intra-Golgi traffic
		TRRAP	Unknown	24705251	Open Targets	ATP-dependent chromatin remodeling Human T-cell leukemia virus 1 infection Formation of the beta-catenin:TCF transactivating complex +1 more
		TSC1	Unknown	24705251	Open Targets	Phospholipase D signaling pathway Autophagy - animal mTOR signaling pathway +15 more
		UBR5	Unknown	24705251	Open Targets	Ubiquitin mediated proteolysis
		USP6	Unknown	24705251	Open Targets	—
		USP9X	Unknown	24705251	Open Targets	Downregulation of SMAD2/3:SMAD4 transcriptional activity Ub-specific processing proteases Synthesis of active ubiquitin: roles of E1 and E2 enzymes +2 more
		VTI1A	Unknown	24705251	Open Targets	SNARE interactions in vesicular transport Intra-Golgi traffic Retrograde transport at the Trans-Golgi-Network
		WNK2	Unknown	24705251	Open Targets	Parathyroid hormone synthesis, secretion and action Stimuli-sensing channels
		WWTR1	Unknown	24705251	Open Targets	Hippo signaling pathway Hippo signaling pathway - multiple species Signaling by Hippo +5 more
		XPO1	Unknown	24705251	Open Targets	Ribosome biogenesis in eukaryotes Nucleocytoplasmic transport Viral life cycle - HIV-1 +15 more
		YAP1	Unknown	24705251	Open Targets	Hippo signaling pathway Hippo signaling pathway - multiple species Nuclear signaling by ERBB4 +5 more
		ZBTB16	Unknown	24705251	Open Targets	Pathways in cancer Transcriptional misregulation in cancer Acute myeloid leukemia +2 more
		ZFHX3	Unknown	24705251	Open Targets	Signaling pathways regulating pluripotency of stem cells RUNX3 regulates CDKN1A transcription
		ZMYM2	Unknown	24705251	Open Targets	Signaling by cytosolic FGFR1 fusion mutants Signaling by FGFR1 in disease
		ZMYM3	Unknown	24705251	Open Targets	—
		ZNF521	Unknown	24705251	Open Targets	—
		ZNRF3	Unknown	24705251	Open Targets	Wnt signaling pathway Regulation of FZD by ubiquitination

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